GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
apoeb APOE ENSDARG00000040295 None Not determined 42
camk2b1 CAMK2B ENSDARG00000011065 5 Not determined 1
camk2b2 CAMK2B ENSDARG00000021065 None Not determined 1
cetp CETP ENSDARG00000030872 1 Not determined 27
DGKB DGKB ENSDARG00000027724 1 Not determined 4
edc4 EDC4 ENSDARG00000062266 2 Not determined 2
fto FTO ENSDARG00000044216 2 Not determined 32
gck GCK ENSDARG00000068006 1 Not determined 7
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 None Not determined 21
mhc1uba MICB ENSDARG00000075963 None Not determined 7
mhc1ze MICB ENSDARG00000074765 None Not determined 7
mhc1zel MICB ENSDARG00000092162 1 Not determined 7
MR1BB_DANRE MTNR1B ENSDARG00000086493 None Not determined 15
mtnr1ba MTNR1B ENSDARG00000053833 None Not determined 15
mtnr1bb MTNR1B ENSDARG00000086883 None Not determined 15
NP_919406.1 MICB ENSDARG00000086877 2 Not determined 7
nr1h3 NR1H3 ENSDARG00000043170 None Not determined 3
Q8MHB3_DANRE MICB ENSDARG00000076734 None Not determined 7
Q8MHB6_DANRE MICB ENSDARG00000088022 None Not determined 7
si:ch1073-189o9.1 MLXIPL ENSDARG00000089107 None Not determined 13
si:ch211-287j19.6 MICB ENSDARG00000001470 1 Not determined 7
si:ch73-213j4.4 MICB ENSDARG00000092731 None Not determined 7
si:dkey-162b3.1 GALNT2 ENSDARG00000003829 4 Not determined 8
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
SMEK2 SMEK2 ENSDARG00000039619 None Not determined 1
tmem195 TMEM195 ENSDARG00000025595 1 Not determined 2
tomm40 TOMM40 ENSDARG00000092112 1 Not determined 23
tomm40l TOMM40 ENSDARG00000036721 None Not determined 23
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
zgc:136614 MICB ENSDARG00000069471 None Not determined 7
zgc:171581 ABCA1 ENSDARG00000079009 5 Not determined 13
zgc:64115 MICB ENSDARG00000036588 2 Not determined 7
znf259 ZNF259 ENSDARG00000043542 1 Not determined 11

The following reported genes could not be linked automatically to a zebrafish gene:

  • G6PC2
  • HCG26
* quick link - http://q.sanger.ac.uk/mugx0391