GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

New gene functions in megakaryopoiesis and platelet formation.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A1A5U5_DANRE DLK1 ENSDARG00000077129 None Not determined 2
A1L2A0_DANRE ITPK1 ENSDARG00000070583 2 Not determined 3
abcc4 ABCC4 ENSDARG00000058953 2 Not determined 4
ak3 AK3 ENSDARG00000058226 2 Normal 3
akap10 AKAP10 ENSDARG00000059549 1 Not determined 1
ap2b1 AP2B1 ENSDARG00000035152 2 Not determined 1
arhgef3 ARHGEF3 ENSDARG00000013834 1 Not determined 6
arhgef3l ARHGEF3 ENSDARG00000037554 1 Not determined 6
arvcfa ARVCF ENSDARG00000074329 1 Not determined 1
arvcfb ARVCF ENSDARG00000061688 1 Not determined 1
B8K0E1_DANRE NLRP6 ENSDARG00000078912 None Not determined 1
BAK1 (2 of 2) BAK1 ENSDARG00000089995 None Not determined 7
baxb BAK1 ENSDARG00000030881 None Not determined 7
baz2a BAZ2A ENSDARG00000058676 1 Not determined 1
brd3a BRD3 ENSDARG00000006527 None Not determined 1
brd3b BRD3 ENSDARG00000035126 3 Not determined 1
brf1a BRF1 ENSDARG00000017835 None Not determined 1
brf1b BRF1 ENSDARG00000005002 4 Not determined 1
cbl CBL ENSDARG00000009958 2 Not determined 1
cbx5 CBX5 ENSDARG00000061187 1 Not determined 1
cd226 CD226 ENSDARG00000045391 None Not determined 5
cd9a CD9 ENSDARG00000005842 1 Not determined 1
cd9b CD9 ENSDARG00000016691 1 Not determined 1
cdkn2b CDKN2A ENSDARG00000037262 None Not determined 25
cmyb MYB ENSDARG00000053666 None Not determined 12
copz1 COPZ1 ENSDARG00000017844 2 Not determined 1
ctsz CTSZ ENSDARG00000043081 None Not determined 2
DLK1 DLK1 ENSDARG00000077725 None Not determined 2
dock8 DOCK8 ENSDARG00000055225 5 Not determined 2
ehd3 EHD3 ENSDARG00000007869 2 Not determined 3
f2r F2R ENSDARG00000060012 1 Not determined 1
F2R (7 of 9) F2R ENSDARG00000023519 None Not determined 1
F2R (2 of 9) F2R ENSDARG00000039891 None Not determined 1
fen1 FEN1 ENSDARG00000011404 3 Not determined 4
grtp1a GRTP1 ENSDARG00000029936 None Not determined 1
grtp1b GRTP1 ENSDARG00000030269 None Not determined 1
hbs1l HBS1L ENSDARG00000036778 1 Not determined 11
irf1 IRF1 ENSDARG00000043492 None Not determined 6
irf11 IRF1 ENSDARG00000032768 None Not determined 6
itga2b ITGA2B ENSDARG00000018687 5 Normal 1
itpk1 ITPK1 ENSDARG00000013056 2 Not determined 3
jmjd1c JMJD1C ENSDARG00000079939 6 Not determined 11
kif1b KIF1B ENSDARG00000037020 4 Not determined 3
LOC100001765 NLRP6 ENSDARG00000086576 None Not determined 1
LOC100002825 RNF145 ENSDARG00000056829 1 Not determined 1
LOC100004576 TAOK1 ENSDARG00000069603 None Not determined 4
LOC100149161 F2R ENSDARG00000086262 None Not determined 1
LOC100149486 WASL ENSDARG00000090628 None Not determined 1
LOC100149909 NLRP6 ENSDARG00000091847 None Not determined 1
LOC100150280 NLRP6 ENSDARG00000074616 None Not determined 1
LOC100330883 GP1BA ENSDARG00000069270 1 Not determined 1
LOC100332226 NLRP6 ENSDARG00000089984 None Not determined 1
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100333521 CTSZ ENSDARG00000052350 None Not determined 2
LOC100334915 TAOK1 ENSDARG00000089925 None Not determined 4
LOC555355 NLRP6 ENSDARG00000093402 None Not determined 1
LOC556398 FAM171A2 ENSDARG00000075249 1 Not determined 1
LOC558552 TUBB1 ENSDARG00000053066 None Not determined 2
LOC563949 GP1BA ENSDARG00000073747 1 Not determined 1
LOC565839 EXOC3L2 ENSDARG00000030782 1 Not determined 1
LOC565986 RNF145 ENSDARG00000002609 None Not determined 1
LOC566782 NLRP6 ENSDARG00000090765 2 Not determined 1
LOC571321 NLRP6 ENSDARG00000090087 None Not determined 1
LOC571586 JMJD1C ENSDARG00000077805 5 Not determined 11
LOC794278 F2R ENSDARG00000090041 1 Not determined 1
LOC794365 F2R ENSDARG00000086236 1 Not determined 1
LOC796962 NLRP6 ENSDARG00000088279 None Not determined 1
LOC797104 FAM171A2 ENSDARG00000079656 2 Not determined 1
LOC799082 F2R ENSDARG00000059507 1 Not determined 1
LOC799227 F2R ENSDARG00000087469 None Not determined 1
mef2ca MEF2C ENSDARG00000029764 1 Not determined 8
mef2cb MEF2C ENSDARG00000009418 1 Not determined 8
mfn2 MFN2 ENSDARG00000079504 3 Normal 1
nfe2 NFE2 ENSDARG00000020606 1 Not determined 1
NLRP6 (81 of 83) NLRP6 ENSDARG00000088689 1 Not determined 1
NLRP6 (80 of 83) NLRP6 ENSDARG00000068453 None Not determined 1
NLRP6 (76 of 83) NLRP6 ENSDARG00000079433 None Not determined 1
NLRP6 (75 of 83) NLRP6 ENSDARG00000091399 1 Not determined 1
NLRP6 (73 of 83) NLRP6 ENSDARG00000088773 None Not determined 1
NLRP6 (72 of 83) NLRP6 ENSDARG00000068621 2 Not determined 1
NLRP6 (69 of 83) NLRP6 ENSDARG00000091292 None Not determined 1
NLRP6 (68 of 83) NLRP6 ENSDARG00000088274 None Not determined 1
NLRP6 (64 of 83) NLRP6 ENSDARG00000086229 1 Not determined 1
NLRP6 (63 of 83) NLRP6 ENSDARG00000089171 None Not determined 1
NLRP6 (60 of 83) NLRP6 ENSDARG00000087251 2 Not determined 1
NLRP6 (59 of 83) NLRP6 ENSDARG00000090193 None Not determined 1
NLRP6 (55 of 83) NLRP6 ENSDARG00000039900 None Not determined 1
NLRP6 (53 of 83) NLRP6 ENSDARG00000075820 None Not determined 1
NLRP6 (47 of 83) NLRP6 ENSDARG00000090101 None Not determined 1
NLRP6 (46 of 83) NLRP6 ENSDARG00000086807 None Not determined 1
NLRP6 (44 of 83) NLRP6 ENSDARG00000079526 None Not determined 1
NLRP6 (40 of 83) NLRP6 ENSDARG00000091357 None Not determined 1
NLRP6 (39 of 83) NLRP6 ENSDARG00000089514 None Not determined 1
NLRP6 (38 of 83) NLRP6 ENSDARG00000080023 None Not determined 1
NLRP6 (37 of 83) NLRP6 ENSDARG00000087189 None Not determined 1
NLRP6 (35 of 83) NLRP6 ENSDARG00000086752 None Not determined 1
NLRP6 (34 of 83) NLRP6 ENSDARG00000088692 1 Not determined 1
NLRP6 (22 of 83) NLRP6 ENSDARG00000090171 None Not determined 1
NLRP6 (20 of 83) NLRP6 ENSDARG00000090399 None Not determined 1
NLRP6 (17 of 83) NLRP6 ENSDARG00000089306 None Not determined 1
NLRP6 (16 of 83) NLRP6 ENSDARG00000090901 None Not determined 1
NLRP6 (15 of 83) NLRP6 ENSDARG00000087306 None Not determined 1
NLRP6 (14 of 83) NLRP6 ENSDARG00000086422 None Not determined 1
NLRP6 (13 of 83) NLRP6 ENSDARG00000088908 None Not determined 1
NLRP6 (12 of 83) NLRP6 ENSDARG00000088775 1 Not determined 1
NLRP6 (11 of 83) NLRP6 ENSDARG00000087885 None Not determined 1
NLRP6 (6 of 83) NLRP6 ENSDARG00000088120 None Not determined 1
NP_001002137.1 PTGES3 ENSDARG00000089626 None Not determined 1
NP_001006099.1 BAZ2A ENSDARG00000090952 None Not determined 1
NP_001099135.1 CABLES1 ENSDARG00000062044 None Not determined 6
pdia5 PDIA5 ENSDARG00000069242 1 Not determined 1
psmd13 PSMD13 ENSDARG00000016239 3 Not determined 1
ptges3a PTGES3 ENSDARG00000037284 1 Normal 1
ptges3b PTGES3 ENSDARG00000058831 None Not determined 1
ptpn11a PTPN11 ENSDARG00000020334 1 Not determined 8
rad51l1 RAD51L1 ENSDARG00000037046 1 Not determined 7
rcl1 RCL1 ENSDARG00000038312 None Not determined 4
rcor1 RCOR1 ENSDARG00000031434 None Not determined 1
rnf145 RNF145 ENSDARG00000032373 1 Not determined 1
RPH3A (2 of 2) RPH3A ENSDARG00000063436 3 Not determined 1
RPH3A (1 of 2) RPH3A ENSDARG00000076712 1 Not determined 1
SATB1 SATB1 ENSDARG00000062621 None Not determined 1
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:busm1-160c18.1 HLA-DOA ENSDARG00000053739 None Not determined 2
si:busm1-194e12.11 HLA-DOA ENSDARG00000055441 None Not determined 2
si:busm1-228j01.3 HLA-DOA ENSDARG00000086294 3 Not determined 2
si:busm1-228j01.5 HLA-DOA ENSDARG00000079593 1 Not determined 2
si:ch1073-403i13.1 HLA-DOA ENSDARG00000001832 None Not determined 2
si:ch211-114l13.10 NLRP6 ENSDARG00000092196 None Not determined 1
si:ch211-114l13.4 NLRP6 ENSDARG00000078246 None Not determined 1
si:ch211-149a19.4 NLRP6 ENSDARG00000079456 None Not determined 1
si:ch211-156p11.1 NLRP6 ENSDARG00000071604 1 Not determined 1
si:ch211-15j1.3 NLRP6 ENSDARG00000092070 None Not determined 1
si:ch211-187g4.1 NLRP6 ENSDARG00000094350 None Not determined 1
si:ch211-191a16.2 NLRP6 ENSDARG00000095665 None Not determined 1
si:ch211-191a16.3 NLRP6 ENSDARG00000077673 1 Not determined 1
si:ch211-194e1.7 NLRP6 ENSDARG00000068127 None Not determined 1
si:ch211-195k18.2 SATB1 ENSDARG00000057649 3 Not determined 1
si:ch211-196h16.4 NLRP6 ENSDARG00000094782 None Not determined 1
si:ch211-196h16.5 NLRP6 ENSDARG00000069264 None Not determined 1
si:ch211-214b16.3 NLRP6 ENSDARG00000089079 None Not determined 1
si:ch211-233m11.1 NLRP6 ENSDARG00000074653 4 Not determined 1
si:ch211-250k18.5 NLRP6 ENSDARG00000068749 None Not determined 1
si:ch211-250k18.6 NLRP6 ENSDARG00000093964 None Not determined 1
si:ch211-250k18.7 NLRP6 ENSDARG00000093761 None Not determined 1
si:ch211-255g12.8 NLRP6 ENSDARG00000069627 1 Not determined 1
si:ch73-211l2.3 HLA-DOA ENSDARG00000075932 1 Not determined 2
si:dkey-11n14.1 NLRP6 ENSDARG00000074881 None Not determined 1
si:dkey-121n8.3 NLRP6 ENSDARG00000078101 None Not determined 1
si:dkey-121n8.4 NLRP6 ENSDARG00000076819 None Not determined 1
si:dkey-121n8.5 NLRP6 ENSDARG00000093532 None Not determined 1
si:dkey-121n8.6 NLRP6 ENSDARG00000095780 None Not determined 1
si:dkey-121n8.7 NLRP6 ENSDARG00000094067 None Not determined 1
si:dkey-121n8.8 NLRP6 ENSDARG00000092025 None Not determined 1
si:dkey-13n15.11 NLRP6 ENSDARG00000078002 1 Not determined 1
si:dkey-19f21.3 DNM3 ENSDARG00000032238 2 Not determined 6
si:dkey-211i20.2 NLRP6 ENSDARG00000092323 None Not determined 1
si:dkey-218h11.6 NLRP6 ENSDARG00000093680 None Not determined 1
si:dkey-222h21.10 NLRP6 ENSDARG00000094608 2 Not determined 1
si:dkey-222h21.11 NLRP6 ENSDARG00000092984 None Not determined 1
si:dkey-222h21.2 NLRP6 ENSDARG00000095719 None Not determined 1
si:dkey-222h21.6 NLRP6 ENSDARG00000092294 None Not determined 1
si:dkey-222h21.7 NLRP6 ENSDARG00000095578 1 Not determined 1
si:dkey-222h21.8 NLRP6 ENSDARG00000094344 None Not determined 1
si:dkey-230i18.1 NLRP6 ENSDARG00000092036 None Not determined 1
si:dkey-230i18.2 NLRP6 ENSDARG00000095528 None Not determined 1
si:dkey-240n22.1 NLRP6 ENSDARG00000095696 1 Not determined 1
si:dkey-253d23.12 NLRP6 ENSDARG00000078234 3 Not determined 1
si:dkey-275m12.1 KALRN ENSDARG00000078117 2 Not determined 1
si:dkey-41c6.3 NLRP6 ENSDARG00000087615 None Not determined 1
si:dkey-45k15.2 C14orf73 ENSDARG00000058180 4 Not determined 3
si:dkey-65b12.4 WDR66 ENSDARG00000059855 4 Not determined 4
si:dkey-85k8.5 EXOC3L2 ENSDARG00000008414 3 Normal 1
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:dkeyp-2h4.2 HLA-DOA ENSDARG00000031745 None Not determined 2
si:rp71-11b17.10 TMCC2 ENSDARG00000046007 None Not determined 2
si:rp71-17i16.5 PIK3CG ENSDARG00000037527 None Not determined 5
si:rp71-69p9.2 ANKMY1 ENSDARG00000062702 4 Not determined 1
si:rp71-7l19.2 NLRP6 ENSDARG00000043792 2 Not determined 1
si:zfos-2070c2.1 HLA-DOA ENSDARG00000070206 None Not determined 2
si:zfos-367g9.1 HLA-DOA ENSDARG00000074816 1 Not determined 2
tpm1 TPM1 ENSDARG00000087402 None Not determined 3
tpm3 TPM4 ENSDARG00000005162 3 Not determined 2
tpm3 TPM1 ENSDARG00000005162 3 Not determined 3
tpma TPM1 ENSDARG00000033683 None Not determined 3
vwf VWF ENSDARG00000077231 5 Not determined 2
wasla WASL ENSDARG00000014113 1 Not determined 1
waslb WASL ENSDARG00000006283 2 Not determined 1
zfpm2a ZFPM2 ENSDARG00000040123 None Not determined 5
zfpm2b ZFPM2 ENSDARG00000035997 1 Not determined 5
zgc:112307 TAOK1 ENSDARG00000077159 None Not determined 4
zgc:113068 THADA ENSDARG00000053082 1 Not determined 10
zgc:123107 HLA-DOA ENSDARG00000020286 None Not determined 2
zgc:136791 NLRP6 ENSDARG00000091320 None Not determined 1
zgc:136817 KALRN ENSDARG00000063538 None Not determined 1
zgc:153993 BAK1 ENSDARG00000068102 None Not determined 7
zgc:158564 KIAA0232 ENSDARG00000052244 None Not determined 1
zgc:162892 ANKDD1A ENSDARG00000074485 None Not determined 1
zgc:171965 F2R ENSDARG00000077638 1 Not determined 1
zgc:194906 NLRP6 ENSDARG00000074088 2 Not determined 1
zgc:65811 CD9 ENSDARG00000044990 None Not determined 1
zgc:77033 PIK3CG ENSDARG00000017757 1 Not determined 5

The following reported genes could not be linked automatically to a zebrafish gene:

  • C14orf70
  • FLJ36031
  • FLJ36031
  • HLA-B
  • HSD17B13
  • LOC148824
  • LRRC16
  • MLSTD1
  • PLEC1
  • SIRPA
  • SNORD7
  • SNORD7
  • SYN2
  • THPO
  • TRIM58
* quick link - http://q.sanger.ac.uk/jwdxjkr0