GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association of lipid-lowering response to statins in combined study populations.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcb5 ABCB5 ENSDARG00000021787 2 Not determined 2
acvr2a ACVR2A ENSDARG00000011188 None Not determined 2
ACVR2A (2 of 2) ACVR2A ENSDARG00000079944 2 Not determined 2
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
arhgef16 ARHGEF16 ENSDARG00000077114 2 Not determined 1
bcat1 BCAT1 ENSDARG00000045568 None Not determined 2
celsr1a CELSR2 ENSDARG00000069185 3 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 3 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 1 Not determined 17
CHL1 (1 of 2) CHL1 ENSDARG00000076233 3 Not determined 7
chl1a CHL1 ENSDARG00000077881 4 Not determined 7
cldn17 CLDN8 ENSDARG00000092338 None Not determined 1
cldn17 CLDN17 ENSDARG00000092338 None Not determined 1
cldnk CLDN8 ENSDARG00000042357 1 Normal 1
cldnk CLDN17 ENSDARG00000042357 1 Normal 1
cntnap2 CNTNAP5 ENSDARG00000074558 None Not determined 4
cntnap5 CNTNAP5 ENSDARG00000073802 7 Not determined 4
COBLL1 (2 of 2) COBLL1 ENSDARG00000089858 None Not determined 3
COBLL1 (1 of 2) COBLL1 ENSDARG00000088979 None Not determined 3
col19a1 COL19A1 ENSDARG00000076163 2 Not determined 1
dicer1 DICER1 ENSDARG00000001129 5 Not determined 2
disc1 DISC1 ENSDARG00000021895 4 Not determined 5
dusp4 DUSP4 ENSDARG00000044688 1 Not determined 1
fads2 FADS2 ENSDARG00000019532 None Not determined 15
gpd2 GPD2 ENSDARG00000062430 3 Not determined 1
GRB14 GRB14 ENSDARG00000068280 None Not determined 5
grik1a GRIK1 ENSDARG00000069139 2 Not determined 6
id4 ID4 ENSDARG00000045131 None Not determined 3
KIF13B (2 of 2) KIF13B ENSDARG00000073859 3 Not determined 2
kif13ba KIF13B ENSDARG00000079731 3 Not determined 2
LOC100001603 FAM5C ENSDARG00000061051 2 Not determined 2
LOC100330048 FAM5C ENSDARG00000075352 None Not determined 2
LOC100334365 CLDN8 ENSDARG00000040928 None Not determined 1
LOC100334365 CLDN17 ENSDARG00000040928 None Not determined 1
LOC100334409 CNTNAP5 ENSDARG00000074351 None Not determined 4
LOC559157 CNTNAP5 ENSDARG00000058969 1 Not determined 4
LOC561540 GRIK1 ENSDARG00000040627 3 Not determined 6
LOC570842 CLDN8 ENSDARG00000026095 None Not determined 1
LOC570842 CLDN17 ENSDARG00000026095 None Not determined 1
mcfd2 MCFD2 ENSDARG00000039757 None Not determined 1
NP_571844.1 CLDN17 ENSDARG00000058880 None Not determined 1
NP_571844.1 CLDN8 ENSDARG00000058880 None Not determined 1
nr4a2a NR4A2 ENSDARG00000017007 None Not determined 2
nr4a2b NR4A2 ENSDARG00000044532 2 Not determined 2
prdm16 PRDM16 ENSDARG00000078324 2 Not determined 2
rbm38 RBM38 ENSDARG00000058818 1 Not determined 3
rmi1 RMI1 ENSDARG00000041376 None Not determined 1
rngtt RNGTT ENSDARG00000032261 None Not determined 2
si:ch211-106k21.6 GLIS1 ENSDARG00000068580 1 Not determined 1
si:ch211-119o8.6 ZNF679 ENSDARG00000026972 1 Not determined 1
si:ch211-122m3.1 CNTNAP5 ENSDARG00000067824 5 Not determined 4
si:ch211-137a8.2 CLMN ENSDARG00000068926 3 Normal 4
si:ch211-158d24.2 MEGF9 ENSDARG00000078536 2 Not determined 1
si:ch211-241d21.1 GLIS1 ENSDARG00000027933 1 Not determined 1
si:ch211-247h9.1 CNTN6 ENSDARG00000062880 3 Not determined 3
si:ch211-93n23.6 TTC7A ENSDARG00000074760 2 Normal 2
si:ch73-150k18.1 CNTNAP5 ENSDARG00000075189 3 Not determined 4
si:dkey-155f10.1 CNTNAP5 ENSDARG00000073920 4 Not determined 4
si:dkey-159a18.1 SORT1 ENSDARG00000056145 1 Not determined 13
si:dkey-220k22.1 MEGF9 ENSDARG00000035471 None Not determined 1
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 3 Not determined 17
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-74a11.2 ASB18 ENSDARG00000012948 1 Not determined 1
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
sort1a SORT1 ENSDARG00000029402 None Not determined 13
sort1b SORT1 ENSDARG00000056252 7 Not determined 13
sostdc1a SOSTDC1 ENSDARG00000068892 1 Not determined 1
sostdc1b SOSTDC1 ENSDARG00000056021 None Not determined 1
sox5 SOX5 ENSDARG00000011582 2 Not determined 6
sp8a SP8 ENSDARG00000011870 1 Not determined 2
sp8b SP8 ENSDARG00000056666 1 Not determined 2
strumpellin KIAA0196 ENSDARG00000017190 1 Not determined 1
trib1 TRIB1 ENSDARG00000076142 1 Not determined 12
unc5a BAI3 ENSDARG00000074543 1 Not determined 4
zgc:100997 CLMN ENSDARG00000043667 1 Not determined 4
zgc:101798 MBOAT1 ENSDARG00000029356 1 Not determined 2
zgc:103471 LMBRD1 ENSDARG00000052307 1 Not determined 1
zgc:110333 CLDN17 ENSDARG00000040628 None Not determined 1
zgc:110333 CLDN8 ENSDARG00000040628 None Not determined 1
zgc:153049 COL19A1 ENSDARG00000069130 None Not determined 1
zgc:153573 CNTN6 ENSDARG00000019405 1 Not determined 3
zgc:163001 BAI3 ENSDARG00000059832 3 Not determined 4
zgc:175108 FAM5C ENSDARG00000076351 3 Not determined 2
zgc:194590 NSMCE2 ENSDARG00000076379 None Not determined 1
zgc:55582 CDK5RAP2 ENSDARG00000024219 6 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • ACTBP8
  • ANXA2P3
  • C13orf7
  • CTCFL
  • DISC2
  • DMRTB1
  • F11
  • FADS1
  • FADS1
  • FADS3
  • FEN
  • FLJ21820
  • FLJ32894
  • FLJ40172
  • FLJ40434
  • FLJ45244
  • GDF7
  • HMG1L1
  • IQCA
  • KLKB1
  • LOC283904
  • LOC390415
  • LOC401864
  • LOC402123
  • LOC402123
  • LOC402642
  • LOC441546
  • LOC442320
  • LOC442511
  • LOC544042
  • LOC644119
  • LOC644282
  • LOC644325
  • LOC645084
  • LOC646909
  • LOC647065
  • LOC647132
  • LOC647298
  • LOC727878
  • LOC728038
  • LOC728087
  • LOC728184
  • LOC728209
  • LOC728927
  • LOC729105
  • LOC729388
  • LOC729464
  • LOC729920
  • MEFGF6
  • MIRN147
  • MRPS36P2
  • ORC4L
  • PSRC1
  • RPL7AP1
  • SIA1L2
  • SLC28A3
* quick link - http://q.sanger.ac.uk/6t0l6w1w