GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
atg5 ATG5 ENSDARG00000023396 1 Not determined 2
bltk BLK ENSDARG00000007783 2 Not determined 11
hic1l HIC2 ENSDARG00000045660 1 Not determined 1
ikzf1 IKZF1 ENSDARG00000013539 3 Not determined 10
irf5 IRF5 ENSDARG00000045681 None Not determined 14
LOC568967 LRRC18 ENSDARG00000076236 None Not determined 2
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
prdm1a PRDM1 ENSDARG00000002445 3 Not determined 3
prdm1b PRDM1 ENSDARG00000053592 4 Not determined 3
prdm1c PRDM1 ENSDARG00000078161 None Not determined 3
rasgrp3 RASGRP3 ENSDARG00000077864 None Not determined 3
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 1 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 None Not determined 35
si:ch211-274c22.6 TNFAIP3 ENSDARG00000027777 4 Not determined 11
si:dkey-70o15.2 WDFY4 ENSDARG00000077009 6 Not determined 4
si:dkey-70o15.3 LRRC18 ENSDARG00000078790 None Not determined 2
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
stat4 STAT4 ENSDARG00000028731 2 Not determined 19
tnip1 TNIP1 ENSDARG00000015653 2 Not determined 6
ube2l3a UBE2L3 ENSDARG00000019188 None Not determined 8
ube2l3b UBE2L3 ENSDARG00000027141 None Not determined 8
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:153067 HLA-DRB1 ENSDARG00000056330 1 Not determined 35
zgc:63767 SLC15A4 ENSDARG00000000384 2 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • ETS1
  • TNFSF4
* quick link - http://q.sanger.ac.uk/i80jnths