GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcg2a ABCG2 ENSDARG00000043037 None Not determined 10
abcg2b ABCG2 ENSDARG00000079361 None Not determined 10
abcg2c ABCG2 ENSDARG00000058574 3 Not determined 10
abcg2d ABCG2 ENSDARG00000016818 1 Not determined 10
LOC100001249 SLC22A12 ENSDARG00000054690 None Not determined 4
LOC100001249 SLC22A11 ENSDARG00000054690 None Not determined 4
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
NP_001107902.1 SLC2A9 ENSDARG00000063288 3 1 phenotype 14
pdzk1 PDZK1 ENSDARG00000022261 None Not determined 3
si:ch1073-210b3.2 LRRC16A ENSDARG00000077661 None Not determined 3
si:dkey-119m7.4 SLC22A11 ENSDARG00000071049 4 Normal 4
si:dkey-119m7.4 SLC22A12 ENSDARG00000071049 4 Normal 4
slc16a9a SLC16A9 ENSDARG00000013926 1 Not determined 3
slc16a9b SLC16A9 ENSDARG00000005947 2 Not determined 3
slc2a11b SLC2A9 ENSDARG00000093395 2 1 phenotype 14
slc2a15a SLC2A9 ENSDARG00000029894 None Not determined 14
slc2a15b SLC2A9 ENSDARG00000053269 1 Not determined 14
zgc:100843 SCGN ENSDARG00000058732 2 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • SLC17A1
* quick link - http://q.sanger.ac.uk/7ewlb389