GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abca1a ABCA1 ENSDARG00000074635 11 Not determined 13
abcg5 ABCG5 ENSDARG00000063078 4 Normal 2
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa4 APOA1 ENSDARG00000040298 2 Not determined 13
apoa4 APOA4 ENSDARG00000040298 2 Not determined 11
apoa4 APOA5 ENSDARG00000040298 2 Not determined 22
apob APOB ENSDARG00000042780 11 Not determined 17
apobl APOB ENSDARG00000022767 11 Not determined 17
apoeb APOE ENSDARG00000040295 1 Not determined 42
celsr1a CELSR2 ENSDARG00000069185 8 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 4 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 2 Not determined 17
cetp CETP ENSDARG00000030872 2 Not determined 27
ctcf CTCF ENSDARG00000056621 1 Not determined 1
dnah9l DNAH11 ENSDARG00000062630 14 Not determined 5
dock7 DOCK7 ENSDARG00000078675 7 Not determined 5
fads2 FADS2 ENSDARG00000019532 None Not determined 15
hmgcra HMGCR ENSDARG00000052734 4 Not determined 9
hmgcrb HMGCR ENSDARG00000059301 1 Not determined 9
ldlr LDLR ENSDARG00000029476 3 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
lipg LIPG ENSDARG00000031044 2 Not determined 9
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 2 Not determined 21
madd MADD ENSDARG00000003495 8 Not determined 4
ncana NCAN ENSDARG00000067820 2 Not determined 4
ncanb NCAN ENSDARG00000005783 1 Not determined 4
PRMT8 (1 of 2) PRMT8 ENSDARG00000040633 None Not determined 1
prmt8b PRMT8 ENSDARG00000045760 2 Not determined 1
si:ch1073-189o9.1 MLXIPL ENSDARG00000089107 None Not determined 13
si:dkey-12h9.6 TMEM57 ENSDARG00000056092 1 Not determined 3
si:dkey-233k19.3 DNAH11 ENSDARG00000094282 6 Not determined 5
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 4 Not determined 17
si:dkey-6h5.1 DNAH11 ENSDARG00000077384 15 Not determined 5
si:dkey-7f3.15 APOA1 ENSDARG00000094929 3 Not determined 13
si:dkey-7f3.15 APOA4 ENSDARG00000094929 3 Not determined 11
si:dkey-7f3.15 APOA5 ENSDARG00000094929 3 Not determined 22
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 5 Not determined 17
tmem57a TMEM57 ENSDARG00000005625 3 Not determined 3
tmem57b TMEM57 ENSDARG00000012741 3 Not determined 3
tomm40 TOMM40 ENSDARG00000092112 1 Not determined 23
tomm40l TOMM40 ENSDARG00000036721 None Not determined 23
trib1 TRIB1 ENSDARG00000076142 1 Not determined 12
zgc:110064 APOE ENSDARG00000086370 1 Not determined 42
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:171581 ABCA1 ENSDARG00000079009 7 Not determined 13
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:56429 FOLH1 ENSDARG00000021383 2 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC3
  • APOC3
  • APOC3
  • FADS3
  • FADS3
  • FADS3
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