GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Identification of ten loci associated with height highlights new biological pathways in human growth.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ADAMTSL3 ADAMTSL3 ENSDARG00000027903 6 Not determined 8
ANKFN1 (2 of 2) ANKFN1 ENSDARG00000060941 None Not determined 2
ANKFN1 (1 of 2) ANKFN1 ENSDARG00000074494 None Not determined 2
ATXN3L ATXN3 ENSDARG00000009264 None Not determined 3
chchd7 CHCHD7 ENSDARG00000068156 None Not determined 2
dot1l DOT1L ENSDARG00000061992 5 Normal 3
gdf5 GDF5 ENSDARG00000002760 1 Not determined 5
gdf7 GDF5 ENSDARG00000042784 None Not determined 5
gpr126 GPR126 ENSDARG00000054137 3 1 phenotype 9
hhip HHIP ENSDARG00000060397 1 Not determined 13
hmga2 HMGA2 ENSDARG00000069912 None Not determined 18
LIN28B LIN28B ENSDARG00000052511 None Not determined 11
LOC100333070 HIST1H1D ENSDARG00000088889 None Not determined 2
LOC100333275 HIST1H1D ENSDARG00000075508 None Not determined 2
LOC100334833 HMGA2 ENSDARG00000091038 None Not determined 18
LOC560910 HIST1H1D ENSDARG00000032637 None Not determined 2
LOC569515 CDK6 ENSDARG00000030163 1 Not determined 8
LOC573073 HIST1H1D ENSDARG00000051718 None Not determined 2
nkx2.1b NKX2-1 ENSDARG00000019835 None Not determined 2
PAPPA (1 of 2) PAPPA ENSDARG00000059544 3 Not determined 2
rab40c RAB40C ENSDARG00000061208 1 Not determined 2
sh3gl3 SH3GL3 ENSDARG00000007302 None Not determined 3
si:ch211-103n10.5 HIST1H1D ENSDARG00000077504 None Not determined 2
si:ch211-196f15.1 PAPPA ENSDARG00000059858 8 Not determined 2
si:ch211-234f14.1 CDK6 ENSDARG00000070228 None Not determined 8
si:ch73-160p19.2 ZBTB38 ENSDARG00000077426 None Not determined 12
trip11 TRIP11 ENSDARG00000078381 2 Not determined 3
WDR60 WDR60 ENSDARG00000076934 None Not determined 1
zgc:101598 FUBP3 ENSDARG00000087058 None Not determined 3
zgc:110216 HIST1H1D ENSDARG00000077456 None Not determined 2
zgc:110380 HIST1H1D ENSDARG00000035519 None Not determined 2
zgc:110425 HIST1H1D ENSDARG00000058479 None Not determined 2
zgc:153206 UQCC ENSDARG00000068176 None Not determined 6
zgc:158742 SH3GL3 ENSDARG00000013360 None Not determined 3
zgc:163061 HIST1H1D ENSDARG00000075538 None Not determined 2
zgc:163061 HIST1H1D ENSDARG00000076766 None Not determined 2
zgc:171531 NKX2-1 ENSDARG00000075107 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • RDHE2
* quick link - http://q.sanger.ac.uk/ovtyh60h