Genevar Quick Start: cis-eQTL – Gene
Snapshot
In this example:
- Observed eQTLs in a 2-Mb window around the GBP3 locus in HapMap3 CHB
- Significant SNPs within the chromosome region are listed below
- Dotted line represents the 0.001 p-value threshold
- Information of SNPs will be displayed in a tip text when hovering the cursor over the SNP of interest
- Results can be saved as a PNG diagram or exported as a tab-delimited list
- External links to three major genome browsers
Step-by-Step Guide
- Click on "cis-eQTL – Gene".
- Select a dataset of interest (e.g. HapMap3).
- Choose reference source (e.g. Ensembl).
- Type in gene symbol of interest (e.g. GBP3).
- Match entire word (optional)?
- Submit and search from the selected dataset and reference.
- Query results will be listed here.
- Select genes of interest.
- Submit to find matched transcripts.
- A new tree node containing matched trascripts for each gene will be added here. Click on this node.
- Select populations of interest.
- Select probes of interest.
- Set parameters (e.g. Spearman's rho, 1 Mb, p < 0.001).
- Submit to get mapping results.
- New tree nodes containing mapping results for each populaiton will be added here. Click on one of them.












