The chimpanzee malaria parasite P. reichenowi is phylogenetically close to the human parasite P. falciparum and whole genome comparisons should reveal crucial information about the evolution of host specificity.
A low (1-2x) coverage draft genome sequence was previously produced by Sanger sequencing from the only known source of P. reichenowi genomic DNA (CDC strain) provided by Alan Thomas (BPRC, Netherlands). Following the discovery of an additional aliquot of the same DNA source, a full genome sequence has been produced using Illumina Sequence-by-Synthesis. The complete and annotated genome, compared with that of P. falciparum has been published (PMID:25203297).
Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts.
Nature communications 2014;5;4754
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