Plasmodium chabaudi

P. chabaudi is one of the four malaria species that infect murine rodents from Central Africa that are infectious to laboratory rodents and easily maintained and transmitted by Anopheles stephensi in the laboratory. It serves as a good model for the human parasites with which it shares high homology in most essential aspects of structure, biochemistry and life cycle. Genome organisation is conserved between rodent and human parasites and the two share detailed synteny.

Data Downloads

[Genome Research Limited]

An initial analysis of a low-coverage (3x) draft genome produced by Sanger-sequencing was published by Hall et al. in 2005. From these data P. chabaudi has an estimated genome size of 18-20 Mb, with 14 chromosomes in the size range of 0.6 Mb to 3.8 Mb. DNA for this sequencing project was obtained from bloodstages of clone AS of of P. chabaudi.

Further sequencing of P. chabaudi AS and several other strains has been completed using Illumina Sequence-by-synthesis technology. A publication describing the comprehensive re-assembly and annotation is underway. Please refer to Data Use Statement.

Studies

Simultaneous host-parasite RNA sequencing of rodent malaria infection time course

Sample

Strain

Run Accession

P-19_RNAPlasmodium chabaudi chabaudi ASERR274011
P-19_RNAPlasmodium chabaudi chabaudi ASERR273996
P-19_RNAPlasmodium chabaudi chabaudi ASERR273981
P-16_RNAPlasmodium chabaudi chabaudi ASERR274010
P-16_RNAPlasmodium chabaudi chabaudi ASERR273995
P-16_RNAPlasmodium chabaudi chabaudi ASERR273980
P-13_RNAPlasmodium chabaudi chabaudi ASERR274009
P-13_RNAPlasmodium chabaudi chabaudi ASERR273994
P-13_RNAPlasmodium chabaudi chabaudi ASERR273979
P-10_RNAPlasmodium chabaudi chabaudi ASERR274008
P-10_RNAPlasmodium chabaudi chabaudi ASERR273993
P-10_RNAPlasmodium chabaudi chabaudi ASERR273978
P-1_RNAPlasmodium chabaudi chabaudi ASERR274005
P-1_RNAPlasmodium chabaudi chabaudi ASERR273990
P-1_RNAPlasmodium chabaudi chabaudi ASERR273975
P-7_RNAPlasmodium chabaudi chabaudi ASERR274007
P-7_RNAPlasmodium chabaudi chabaudi ASERR273992
P-7_RNAPlasmodium chabaudi chabaudi ASERR273977
P-4_RNAPlasmodium chabaudi chabaudi ASERR274006
P-4_RNAPlasmodium chabaudi chabaudi ASERR273991
P-4_RNAPlasmodium chabaudi chabaudi ASERR273976
P-21_RNAPlasmodium chabaudi chabaudi ASERR274101
P-21_RNAPlasmodium chabaudi chabaudi ASERR274086
P-21_RNAPlasmodium chabaudi chabaudi ASERR274071
P-18_RNAPlasmodium chabaudi chabaudi ASERR274100
P-18_RNAPlasmodium chabaudi chabaudi ASERR274085
P-18_RNAPlasmodium chabaudi chabaudi ASERR274070
P-15_RNAPlasmodium chabaudi chabaudi ASERR274099
P-15_RNAPlasmodium chabaudi chabaudi ASERR274084
P-15_RNAPlasmodium chabaudi chabaudi ASERR274069
P-12_RNAPlasmodium chabaudi chabaudi ASERR274098
P-12_RNAPlasmodium chabaudi chabaudi ASERR274083
P-12_RNAPlasmodium chabaudi chabaudi ASERR274068
P-9_RNAPlasmodium chabaudi chabaudi ASERR274097
P-9_RNAPlasmodium chabaudi chabaudi ASERR274082
P-9_RNAPlasmodium chabaudi chabaudi ASERR274067
P-6_RNAPlasmodium chabaudi chabaudi ASERR274096
P-6_RNAPlasmodium chabaudi chabaudi ASERR274081
P-6_RNAPlasmodium chabaudi chabaudi ASERR274066
P-3_RNAPlasmodium chabaudi chabaudi ASERR274095
P-3_RNAPlasmodium chabaudi chabaudi ASERR274080
P-3_RNAPlasmodium chabaudi chabaudi ASERR274065
P-20_RNAPlasmodium chabaudi chabaudi ASERR274056
P-20_RNAPlasmodium chabaudi chabaudi ASERR274041
P-20_RNAPlasmodium chabaudi chabaudi ASERR274026
P-17_RNAPlasmodium chabaudi chabaudi ASERR274055
P-17_RNAPlasmodium chabaudi chabaudi ASERR274040
P-17_RNAPlasmodium chabaudi chabaudi ASERR274025
P-14_RNAPlasmodium chabaudi chabaudi ASERR274054
P-14_RNAPlasmodium chabaudi chabaudi ASERR274039
P-14_RNAPlasmodium chabaudi chabaudi ASERR274024
P-11_RNAPlasmodium chabaudi chabaudi ASERR274053
P-11_RNAPlasmodium chabaudi chabaudi ASERR274038
P-11_RNAPlasmodium chabaudi chabaudi ASERR274023
P-8_RNAPlasmodium chabaudi chabaudi ASERR274052
P-8_RNAPlasmodium chabaudi chabaudi ASERR274037
P-8_RNAPlasmodium chabaudi chabaudi ASERR274022
P-5_RNAPlasmodium chabaudi chabaudi ASERR274051
P-5_RNAPlasmodium chabaudi chabaudi ASERR274036
P-5_RNAPlasmodium chabaudi chabaudi ASERR274021
P-2_RNAPlasmodium chabaudi chabaudi ASERR274050
P-2_RNAPlasmodium chabaudi chabaudi ASERR274035
P-2_RNAPlasmodium chabaudi chabaudi ASERR274020

RNA sequencing of the intra-erythrocytic lifecycle of Plasmodium chabaudi

Sample

Strain

Run Accession

Pc23hC_RNAPlasmodium chabaudi chabaudi ASERR305996
Pc23hC_RNAPlasmodium chabaudi chabaudi ASERR306020
Pc20hC_RNAPlasmodium chabaudi chabaudi ASERR305995
Pc20hC_RNAPlasmodium chabaudi chabaudi ASERR306019
Pc17hC_RNAPlasmodium chabaudi chabaudi ASERR306018
Pc17hC_RNAPlasmodium chabaudi chabaudi ASERR305994
Pc14hC_RNAPlasmodium chabaudi chabaudi ASERR305993
Pc14hC_RNAPlasmodium chabaudi chabaudi ASERR306017
Pc11hC_RNAPlasmodium chabaudi chabaudi ASERR306016
Pc11hC_RNAPlasmodium chabaudi chabaudi ASERR305992
Pc8hC_RNAPlasmodium chabaudi chabaudi ASERR305991
Pc8hC_RNAPlasmodium chabaudi chabaudi ASERR306015
Pc5hC_RNAPlasmodium chabaudi chabaudi ASERR305990
Pc5hC_RNAPlasmodium chabaudi chabaudi ASERR306014
Pc2hC_RNAPlasmodium chabaudi chabaudi ASERR305989
Pc2hC_RNAPlasmodium chabaudi chabaudi ASERR306013
Pc23hB_RNAPlasmodium chabaudi chabaudi ASERR305988
Pc23hB_RNAPlasmodium chabaudi chabaudi ASERR306012
Pc20hB_RNAPlasmodium chabaudi chabaudi ASERR305987
Pc20hB_RNAPlasmodium chabaudi chabaudi ASERR306011
Pc17hB_RNAPlasmodium chabaudi chabaudi ASERR306010
Pc17hB_RNAPlasmodium chabaudi chabaudi ASERR305986
Pc14hB_RNAPlasmodium chabaudi chabaudi ASERR305985
Pc14hB_RNAPlasmodium chabaudi chabaudi ASERR306009
Pc11hB_RNAPlasmodium chabaudi chabaudi ASERR305984
Pc11hB_RNAPlasmodium chabaudi chabaudi ASERR306008
Pc8hB_RNAPlasmodium chabaudi chabaudi ASERR305983
Pc8hB_RNAPlasmodium chabaudi chabaudi ASERR306007
Pc5hB_RNAPlasmodium chabaudi chabaudi ASERR305982
Pc5hB_RNAPlasmodium chabaudi chabaudi ASERR306006
Pc2hB_RNAPlasmodium chabaudi chabaudi ASERR305981
Pc2hB_RNAPlasmodium chabaudi chabaudi ASERR306005
Pc23hA_RNAPlasmodium chabaudi chabaudi ASERR305980
Pc23hA_RNAPlasmodium chabaudi chabaudi ASERR306004
Pc20hA_RNAPlasmodium chabaudi chabaudi ASERR305979
Pc20hA_RNAPlasmodium chabaudi chabaudi ASERR306003
Pc17hA_RNAPlasmodium chabaudi chabaudi ASERR305978
Pc17hA_RNAPlasmodium chabaudi chabaudi ASERR306002
Pc14hA_RNAPlasmodium chabaudi chabaudi ASERR306001
Pc14hA_RNAPlasmodium chabaudi chabaudi ASERR305977
Pc11hA_RNAPlasmodium chabaudi chabaudi ASERR305976
Pc11hA_RNAPlasmodium chabaudi chabaudi ASERR306000
Pc8hA_RNAPlasmodium chabaudi chabaudi ASERR305975
Pc8hA_RNAPlasmodium chabaudi chabaudi ASERR305999
Pc5hA_RNAPlasmodium chabaudi chabaudi ASERR305974
Pc5hA_RNAPlasmodium chabaudi chabaudi ASERR305998
Pc2hA_RNAPlasmodium chabaudi chabaudi ASERR305997
Pc2hA_RNAPlasmodium chabaudi chabaudi ASERR305973

Antigenic variation in recrudescent Plasmodium chabaudi infection

Sample

Strain

Run Accession

T1_21-14_RNAPlasmodium chabaudi chabaudi ASERR411965
T1_21-4_RNAPlasmodium chabaudi chabaudi ASERR411964
T2_20-14_RNAPlasmodium chabaudi chabaudi ASERR411963
T2_21-1_RNAPlasmodium chabaudi chabaudi ASERR411962
T2_21-2_RNAPlasmodium chabaudi chabaudi ASERR411961
T1_21-2_RNAPlasmodium chabaudi chabaudi ASERR411960
T1_21-1_RNAPlasmodium chabaudi chabaudi ASERR411959
T1_20-14_RNAPlasmodium chabaudi chabaudi ASERR411958
T2_21-4_RNAPlasmodium chabaudi chabaudi ASERR411957
T2_21-14_RNAPlasmodium chabaudi chabaudi ASERR411956
T2_47-1_RNAPlasmodium chabaudi chabaudi ASERR559266
T2_47-1_RNAPlasmodium chabaudi chabaudi ASERR563593
T2_47-1_RNAPlasmodium chabaudi chabaudi ASERR563617
T2_45-6_RNAPlasmodium chabaudi chabaudi ASERR559265
T2_45-6_RNAPlasmodium chabaudi chabaudi ASERR563616
T2_45-6_RNAPlasmodium chabaudi chabaudi ASERR563592
T1_46-4_RNAPlasmodium chabaudi chabaudi ASERR559264
T1_46-4_RNAPlasmodium chabaudi chabaudi ASERR563615
T1_46-4_RNAPlasmodium chabaudi chabaudi ASERR563591
T1_43-6_RNAPlasmodium chabaudi chabaudi ASERR559263
T1_43-6_RNAPlasmodium chabaudi chabaudi ASERR563614
T1_43-6_RNAPlasmodium chabaudi chabaudi ASERR563590
T1_47-4_RNAPlasmodium chabaudi chabaudi ASERR559262
T1_47-4_RNAPlasmodium chabaudi chabaudi ASERR563613
T1_47-4_RNAPlasmodium chabaudi chabaudi ASERR563589
T1_43-2_RNAPlasmodium chabaudi chabaudi ASERR559261
T1_43-2_RNAPlasmodium chabaudi chabaudi ASERR563612
T1_43-2_RNAPlasmodium chabaudi chabaudi ASERR563588
T2_45-4_RNAPlasmodium chabaudi chabaudi ASERR559260
T2_45-4_RNAPlasmodium chabaudi chabaudi ASERR563587
T2_45-4_RNAPlasmodium chabaudi chabaudi ASERR563611
T2_46-4_RNAPlasmodium chabaudi chabaudi ASERR559259
T2_46-4_RNAPlasmodium chabaudi chabaudi ASERR563586
T2_46-4_RNAPlasmodium chabaudi chabaudi ASERR563610
T2_47-2_RNAPlasmodium chabaudi chabaudi ASERR559258
T2_47-2_RNAPlasmodium chabaudi chabaudi ASERR563609
T2_47-2_RNAPlasmodium chabaudi chabaudi ASERR563585
T1_45-6_RNAPlasmodium chabaudi chabaudi ASERR559256
T1_45-6_RNAPlasmodium chabaudi chabaudi ASERR563607
T1_45-6_RNAPlasmodium chabaudi chabaudi ASERR563583
T2_43-6_RNAPlasmodium chabaudi chabaudi ASERR559255
T2_43-6_RNAPlasmodium chabaudi chabaudi ASERR563606
T2_43-6_RNAPlasmodium chabaudi chabaudi ASERR563582
T1_45-2_RNAPlasmodium chabaudi chabaudi ASERR559254
T1_45-2_RNAPlasmodium chabaudi chabaudi ASERR563581
T1_45-2_RNAPlasmodium chabaudi chabaudi ASERR563605
T2_46-6_RNAPlasmodium chabaudi chabaudi ASERR559253
T2_46-6_RNAPlasmodium chabaudi chabaudi ASERR563580
T2_46-6_RNAPlasmodium chabaudi chabaudi ASERR563604
T2_43-2_RNAPlasmodium chabaudi chabaudi ASERR559252
T2_43-2_RNAPlasmodium chabaudi chabaudi ASERR563603
T2_43-2_RNAPlasmodium chabaudi chabaudi ASERR563579
T1_47-1_RNAPlasmodium chabaudi chabaudi ASERR559251
T1_47-1_RNAPlasmodium chabaudi chabaudi ASERR563578
T1_47-1_RNAPlasmodium chabaudi chabaudi ASERR563602
T2_47-4_RNAPlasmodium chabaudi chabaudi ASERR559250
T2_47-4_RNAPlasmodium chabaudi chabaudi ASERR563577
T2_47-4_RNAPlasmodium chabaudi chabaudi ASERR563601
T1_42-7_RNAPlasmodium chabaudi chabaudi ASERR559249
T1_42-7_RNAPlasmodium chabaudi chabaudi ASERR563576
T1_42-7_RNAPlasmodium chabaudi chabaudi ASERR563600
T2_45-2_RNAPlasmodium chabaudi chabaudi ASERR559248
T2_45-2_RNAPlasmodium chabaudi chabaudi ASERR563575
T2_45-2_RNAPlasmodium chabaudi chabaudi ASERR563599
T2_42-1_RNAPlasmodium chabaudi chabaudi ASERR559247
T2_42-1_RNAPlasmodium chabaudi chabaudi ASERR563574
T2_42-1_RNAPlasmodium chabaudi chabaudi ASERR563598
T2_43-3_RNAPlasmodium chabaudi chabaudi ASERR559246
T2_43-3_RNAPlasmodium chabaudi chabaudi ASERR563597
T2_43-3_RNAPlasmodium chabaudi chabaudi ASERR563573
T1_46-6_RNAPlasmodium chabaudi chabaudi ASERR559245
T1_46-6_RNAPlasmodium chabaudi chabaudi ASERR563596
T1_46-6_RNAPlasmodium chabaudi chabaudi ASERR563572
T2_42-7_RNAPlasmodium chabaudi chabaudi ASERR559244
T2_42-7_RNAPlasmodium chabaudi chabaudi ASERR563571
T2_42-7_RNAPlasmodium chabaudi chabaudi ASERR563595
T1_42-1_RNAPlasmodium chabaudi chabaudi ASERR559243
T1_42-1_RNAPlasmodium chabaudi chabaudi ASERR563594
T1_42-1_RNAPlasmodium chabaudi chabaudi ASERR563570
T1_47-2_RNAPlasmodium chabaudi chabaudi ASERR559257
T1_47-2_RNAPlasmodium chabaudi chabaudi ASERR563608
T1_47-2_RNAPlasmodium chabaudi chabaudi ASERR563584

Simultaneous host-parasite RNA sequencing of mosquito transmistted rodent malaria in two host backgrounds

Sample

Strain

Run Accession

B6-21_P_RNAPlasmodium chabaudi chabaudiASERR450142
B6-21_P_RNAPlasmodium chabaudi chabaudiASERR450162
C3-18_P_RNAPlasmodium chabaudi chabaudiASERR450139
C3-18_P_RNAPlasmodium chabaudi chabaudiASERR450159
C3-21_P_RNAPlasmodium chabaudi chabaudiASERR450158
C3-21_P_RNAPlasmodium chabaudi chabaudiASERR450138
B6-12_P_RNAPlasmodium chabaudi chabaudiASERR450132
B6-12_P_RNAPlasmodium chabaudi chabaudiASERR450152
B6-15_P_RNAPlasmodium chabaudi chabaudiASERR450131
B6-15_P_RNAPlasmodium chabaudi chabaudiASERR450151
B6-24_P_RNAPlasmodium chabaudi chabaudiASERR450130
B6-24_P_RNAPlasmodium chabaudi chabaudiASERR450150
B6-18_P_RNAPlasmodium chabaudi chabaudiASERR450127
B6-18_P_RNAPlasmodium chabaudi chabaudiASERR450147
B6-17_P_RNAPlasmodium chabaudi chabaudiASERR455321
B6-17_P_RNAPlasmodium chabaudi chabaudiASERR455302
C3-17_P_RNAPlasmodium chabaudi chabaudiASERR455301
C3-17_P_RNAPlasmodium chabaudi chabaudiASERR455320
B6-23_P_RNAPlasmodium chabaudi chabaudiASERR455300
B6-23_P_RNAPlasmodium chabaudi chabaudiASERR455319
B6-14_P_RNAPlasmodium chabaudi chabaudiASERR455299
B6-14_P_RNAPlasmodium chabaudi chabaudiASERR455318
C3-20_P_RNAPlasmodium chabaudi chabaudiASERR455313
C3-20_P_RNAPlasmodium chabaudi chabaudiASERR455294
B6-20_P_RNAPlasmodium chabaudi chabaudiASERR455293
B6-20_P_RNAPlasmodium chabaudi chabaudiASERR455312
C3-11_P_RNAPlasmodium chabaudi chabaudiASERR455308
C3-11_P_RNAPlasmodium chabaudi chabaudiASERR455289
C3-23_P_RNAPlasmodium chabaudi chabaudiASERR455287
C3-23_P_RNAPlasmodium chabaudi chabaudiASERR455306
C3-12_P_RNAPlasmodium chabaudi chabaudiASERR455265
C3-12_P_RNAPlasmodium chabaudi chabaudiASERR455285
C3-22_P_RNAPlasmodium chabaudi chabaudiASERR455263
C3-22_P_RNAPlasmodium chabaudi chabaudiASERR455283
C3-15_P_RNAPlasmodium chabaudi chabaudiASERR455281
C3-15_P_RNAPlasmodium chabaudi chabaudiASERR455261
B6-16_P_RNAPlasmodium chabaudi chabaudiASERR455258
B6-16_P_RNAPlasmodium chabaudi chabaudiASERR455278
B6-22_P_RNAPlasmodium chabaudi chabaudiASERR455254
B6-22_P_RNAPlasmodium chabaudi chabaudiASERR455274
C3-16_P_RNAPlasmodium chabaudi chabaudiASERR455273
C3-16_P_RNAPlasmodium chabaudi chabaudiASERR455253
B6-19_P_RNAPlasmodium chabaudi chabaudiASERR455271
B6-19_P_RNAPlasmodium chabaudi chabaudiASERR455251
C3-19_P_RNAPlasmodium chabaudi chabaudiASERR455249
C3-19_P_RNAPlasmodium chabaudi chabaudiASERR455269
B6-10_P_RNAPlasmodium chabaudi chabaudiASERR455248
B6-10_P_RNAPlasmodium chabaudi chabaudiASERR455268
  • A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses.

    Hall N, Karras M, Raine JD, Carlton JM, Kooij TW, Berriman M, Florens L, Janssen CS, Pain A, Christophides GK, James K, Rutherford K, Harris B, Harris D, Churcher C, Quail MA, Ormond D, Doggett J, Trueman HE, Mendoza J, Bidwell SL, Rajandream MA, Carucci DJ, Yates JR, Kafatos FC, Janse CJ, Barrell B, Turner CM, Waters AP and Sinden RE

    Science (New York, N.Y.) 2005;307;5706;82-6

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: pathinfo@sanger.ac.uk

* quick link - http://q.sanger.ac.uk/rt8oo5gk