Leishmania donovani is a protozoan parasite belonging to the Trypanosomatid group. As a major human tropical disease causing debilitating visceral and dermal leishmaniasis, examining genomic variation in strains infecting patients can illuminate the molecular mechanisms of its pathogenicity and resistance to drugs.
Work exploring the genome-level variablility in Leishmania donovani at the Sanger is funded under European Framework Project 7 through two consortia, Kaladrug-r and Gemini, created to evaluate the biology of the parasite. More information on Kaladrug-r and on Gemini is available.
Published Genome Data
The genome sequence of Leishmania donovani has not yet been published.
The potential of metabolomics for Leishmania research in the post-genomics era.
Domestic animals and epidemiology of visceral leishmaniasis, Nepal.
Emerging infectious diseases 2010;16;2;231-7
Spread of vector-borne diseases and neglect of Leishmaniasis, Europe.
Emerging infectious diseases 2008;14;7;1013-8
Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.
Proceedings of the National Academy of Sciences of the United States of America 2007;104;22;9375-80
This project is ongoing and and data for this organism will be made available in due course.
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org