This is a Wellcome Trust funded project to sequence the nuclear genome of E. multilocularis, in collaboration with Prof. Klaus Brehm of Institute for Hygiene and Microbiology, University of Wurzburg. The assembled sequence data suggests the genome of E. multilocularis is approximately 110 MB and is being produced by whole genome shotgun sequencing using a mixture of capillary sequencing, illumina sequencing and 454 pyrosequencing. We are also profiling the transcriptome of different life cycle stages of this organism using RNA-seq.

• The genomes of four tapeworm species reveal adaptations to parasitism.

  Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sanchez-Flores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai J, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K, Fernández C, Holland PW, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S, Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G, Wasmuth JD, Zamanian M, Zheng Y, Taenia solium Genome Consortium, Cai X, Soberón X, Olson PD, Laclette JP, Brehm K and Berriman M

  Nature 2013;496;7443;57-63

  PUBMED: 23485966; DOI: 10.1038/nature12031