Streptococcus equi is a Gram-positive bacterium, and is the causative agent of Strangles, the most common infectious disease of horses. The symptoms are severe, complications are common and, at present, there is no effective treatment or vaccine for the disease.
The Sanger Institute has completed the sequencing of and recently published the 2.25 Mb genome of S. equi strain 4047 in collaboration with Prof. Mike Kehoe, of the School of Cell and Molecular Biosciences, University of Newcastle, Duncan Maskell of the Centre for Veterinary Science, Dept. of Clinical Veterinary medicine, The University of Cambridge, and Dr. Neil Chanter of the Centre for Preventative Medicine, Animal Health Trust.
Published Genome Data
The fully annotated genome is available from the EMBL/GenBank databases with accession number FM204883.
Shotgun and assembly data from this project are available from our FTP site.
- Discovery of sequence diversity in Streptococcus equi
- Streptococcus equi genome diversity
- Evolution and transmission of Streptococcus zooepidemicus ST-209 during the 2010 outbreak of respiratory disease in Icelandic horses
- Genome diversity in Streptococcus dysgalactiae subspecies equisimilis
- NCTC 3000
- PacBio sequencing of Streptococcus equi 4592
Evolution and transmission of Streptococcus zooepidemicus ST-209 during the 2010 outbreak of respiratory disease in Icelandic horses
Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens.
PLoS pathogens 2009;5;3;e1000346
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org