Leptospirosis is a zoonotic infection caused by pathogenic members of the genus, primarily L. interrogans. Human disease usually occurs through environmental exposure to soil or water contaminated with Leptospira shed in the urine of an infected animal. Clinical manifestations are broad with symptoms including chills, headache, myalgia, conjunctival suffusion, and abdominal symptoms which can include nausea, vomiting and diarrhea. The disease has a worldwide distribution but is most common in tropical regions where incidence peaks during the rainy season.
The Sanger Institute has been funded by the Wellcome Trust to sequence the genomes from a collection of Leptospira interrogans isolates representing much of the diversity within the species.
This project is ongoing and data for this organism will be made available in due course.
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org