Clostridium botulinum strains produce botulinum neurotoxin, which is the cause of foodborne botulism.
The Sanger Institute has completed the sequence of the genome of Clostridium botulinum, in collaboration with Dr. Roger Huston of the Food Microbial Sciences Unit, University of Reading Department of Food Science, Dr. Nigel Minton of the Institute of Infection, Immunity and Inflammation, University of Nottingham, and Dr. M. Peck of the Food Saftey Microbiology Section, Institute of Food Research.
Published Genome Data
We have sequenced Hall strain A (ATCC 3502) and Eklund 17B. The genome of Hall strain A (ATCC 3502) is 3,886,916 bp in size, with a G+C content of approximately 28.2%. There is also a plasmid of 16,344 bp. The completed sequence for both strains is available for searching on our Blast server, or for download from our FTP site. This project is funded by Beowulf Genomics.
Shotgun and assembly data from this project are available from our FTP site.
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes.
Genome research 2007;17;7;1082-92
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org