Zebrafish paralogous table

Additional paralogous genes and domain architecture for all 92 extracellular proteins are provided.

ZFIN protein names are organised into 62 paralogous clusters. The best full length peptide matches to reference protein library (Ensembl, Refseq, etc) are provided. Pfam and Superfamily domain architecture, and intracellular motifs for each full length protein sequence is also available for reference. All columns are ordered corresponding to the ZFIN protein names in the first column, except for paralogous genes, which are ordered alphabetically.

ZFIN protein name Full length Danio rerio peptide Paralogous clusters in zebrafish PFAM architecture SUPERFAMILY architecture Intracellular motifs
Ncam1
Ncam3 		ENSDARP00000017613
ENSDARP00000021088 		ENSDARG00000007040
ENSDARG00000007220
ENSDARG00000017466
ENSDARG00000055669
ENSDARG00000056181
  • -ig-I-set-I-set-ig-fn3-fn3-TM-
  • -I-set-ig-I-set-I-set-ig-fn3-fn3-TM-
  • -48726-48726-48726-49265-49265-TM-
  • -48726-48726-48726-48726-48726-49265-49265-TM-
  • -PDZ_class1-
  • -Cdk5_Kin-PKC_epsilon-PDZ_class1-
Robo2
Robo1
Robo3a
Robo3b 		ENSDARP00000012875
ENSDARP00000038219
ENSDARP00000027377
ENSDARP00000003540 		ENSDARG00000005645
ENSDARG00000014891
ENSDARG00000026784
  • -I-set-I-set-I-set-I-set-I-set-fn3-fn3-fn3-TM-TM-
  • -I-set-I-set-I-set-TM-I-set-fn3-fn3-fn3-TM-
  • -I-set-I-set-I-set-I-set-I-set-fn3-fn3-fn3-TM-
  • -I-set-I-set-I-set-I-set-I-set-fn3-fn3-fn3-TM-
  • -48726-48726-48726-48726-49265-49265-49265-TM-TM-
  • -48726-48726-TM-48726-49265-49265-49265-TM-
  • -48726-48726-48726-48726-49265-49265-49265-TM-
  • -48726-48726-48726-48726-49265-49265-49265-TM-
  • -No hits-
  • -ErkDD-ErkDD-
  • -ErkDD-Grb2_SH3-Erk1_Kin-ErkDD-GSK3_Kin-ErkDD-
  • -ErkDD-Grb2_SH3-Erk1_Kin-ErkDD-GSK3_Kin-
Ntm
Negr1
Zgc:110372
Zgc:92901 		ENSDARP00000064096
ENSDARP00000038588
ENSDARP00000092401
ENSDARP00000013509 		ENSDARG00000013005
ENSDARG00000018065
ENSDARG00000021607
ENSDARG00000022176
ENSDARG00000053732
  • -I-set-I-set-
  • -V-set-I-set-
  • -V-set-I-set-I-set-
  • -V-set-I-set-ig-
  • -48726-
  • -48726-48726-
  • -48726-48726-
  • -48726-48726-
  • -No hits-
  • -No hits-
  • -No hits-
  • -No hits-
Alcam
Nlcam 		ENSDARP00000033942
ENSDARP00000091978 		ENSDARG00000026531
ENSDARG00000058538
ENSDARG00000069491
  • -C2-set_2-ig-ig-TM-
  • -V-set-C2-set_2-ig-TM-
  • -48726-48726-48726-48726-48726-TM-
  • -48726-48726-48726-48726-TM-
  • -No hits-
  • -Cam_Kin2-
Hapln2 ENSDARP00000026123 ENSDARG00000003903
  • -ig-Xlink-Xlink-
  • -48726-56436-56436-
  • -No hits-
Lingo1b
Lingo1a 		ENSDARP00000052112
ENSDARP00000041819 		ENSDARG00000034165
ENSDARG00000035899
  • -LRRNT-I-set-TM-
  • -LRRNT-I-set-TM-
  • -52058-48726-TM-
  • -52058-48726-TM-
  • -No hits-
  • -No hits-
Flrt1b
Flrt1a
Flrt3 		GENSCAN00000004071
XP_001334421
XP_687230 		GENSCAN00000004071
XP_001334421
XP_687230
  • -TM-LRRNT-LRR_1-LRR_1-LRR_1-LRRCT-fn3-TM-
  • -LRRNT-LRR_1-LRR_1-LRRCT-fn3-TM-
  • -LRRNT-LRRCT-fn3-TM-
  • -TM-52058-TM-
  • -52058-TM-
  • -52058-TM-
  • -No hits-
  • -No hits-
  • -No hits-
Lrrtm2
Lrrtm4l2
Lrrtm4l1
Lrrtm1 		ENSDARP00000096250
XP_697133
XP_001340869
ENSDARP00000069105 		ENSDARG00000052713
ENSDARG00000059535
ENSDARG00000071374
XP_001340869
XP_697133
  • -LRRNT-TM-
  • -LRRNT-LRRCT-TM-
  • -LRR_1-TM-
  • -LRR_1-LRR_1-
  • -52058-TM-
  • -52058-TM-
  • -52058-TM-
  • -52058-
  • -No hits-
  • -No hits-
  • -No hits-
  • -No hits-
Rtn4rl1 ENSDARP00000072426 ENSDARG00000055578
  • -LRRNT-
  • -52058-
  • -No hits-
Vasn ENSDARP00000061073 ENSDARG00000016293
ENSDARG00000032643
  • -LRRNT-LRR_1-EGF-TM-
  • -52058-57196-TM-
  • -No hits-
Lrrc24 XP_001345437 XP_001345437
  • -LRRCT-I-set-TM-
  • -52058-48726-TM-
  • -Casn_Kin1-
Fgfr1b
Fgfr4
Fgfr2
Fgfr3 		ENSDARP00000069753
ENSDARP00000091059
ENSDARP00000075360
ENSDARP00000011898 		ENSDARG00000004782
ENSDARG00000011027
ENSDARG00000011190
ENSDARG00000058115
ENSDARG00000069105
  • -I-set-ig-TM-Pkinase_Tyr-
  • -ig-ig-I-set-ig-TM-Pkinase_Tyr-
  • -I-set-ig-TM-Pkinase_Tyr-
  • -ig-I-set-I-set-TM-Pkinase_Tyr-
  • -48726-48726-TM-56112-
  • -48726-48726-48726-48726-TM-56112-
  • -48726-48726-TM-56112-
  • -48726-48726-48726-TM-56112-
  • -ErkDD-ErkDD-PLCg_NSH2-
  • -Cam_Kin2-PKC_delta-ErkDD-PLCg_NSH2-
  • -Cam_Kin2-Nck_SH2-ErkDD-PDZ_class1-
  • -ErkDD-PLCg_NSH2-
Mag ENSDARP00000023073 ENSDARG00000009965
  • -V-set-ig-I-set-TM-
  • -48726-48726-48726-48726-TM-
  • -PKC_zeta-
Zgc:56201 ENSDARP00000059825 ENSDARG00000040815
  • -No hits-
  • -52058-
  • -No hits-
Lrrn1 ENSDARP00000078824 ENSDARG00000060115
  • -TM-LRR_1-I-set-TM-
  • -TM-52058-48726-TM-
  • -PKC_zeta-PDZ_class2-
Chad ENSDARP00000066263 ENSDARG00000045071
  • -LRRNT-
  • -52058-
  • -No hits-
Unc5b ENSDARP00000045950 ENSDARG00000033327
ENSDARG00000061541
ENSDARG00000062725
  • -I-set-TSP_1-TM-
  • -48726-48726-82895-82895-TM-
  • -No hits-
Lrrc4a
Lrrc4c 		ENSDARP00000091743
ENSDARP00000032214 		ENSDARG00000003020
ENSDARG00000004597
ENSDARG00000014792
ENSDARG00000016739
ENSDARG00000037493
ENSDARG00000069402
  • -LRRNT-I-set-TM-
  • -LRRNT-I-set-TM-
  • -52058-48726-TM-
  • -52058-48726-TM-
  • -PDZ_class1-
  • -PDZ_class1-
Epyc
Optc 		ENSDARP00000092235
ENSDARP00000018034 		ENSDARG00000014358
ENSDARG00000031489
ENSDARG00000044132
ENSDARG00000056950
  • -No hits-
  • -LRRNT-
  • -52058-
  • -52058-
  • -No hits-
  • -No hits-
Elfn1
Elfn2 		XP_688235
XP_698159 		XP_688235
XP_698159
  • -TM-
  • -TM-TM-
  • -52058-TM-
  • -TM-52058-TM-
  • -Akt_Kin-
  • -1433_m1-Casn_Kin2-p85_SH3_m1-ErkDD-Itk_SH3-Cdk5_Kin-
Dcn
Bgn 		ENSDARP00000025940
ENSDARP00000017536 		ENSDARG00000002192
ENSDARG00000002945
ENSDARG00000012066
ENSDARG00000017884
  • -LRRNT-
  • -TM-LRRNT-
  • -52058-
  • -TM-52058-
  • -No hits-
  • -No hits-
Islr2 ENSDARP00000068073 ENSDARG00000051875
  • -LRRCT-I-set-TM-
  • -52058-48726-TM-
  • -DNA_PK-
Sc:d805
Zgc:162468 		ENSDARP00000069664
ENSDARP00000057468 		ENSDARG00000010154
ENSDARG00000053186
  • -TM-V-set-TM-
  • -V-set-TM-
  • -TM-48726-TM-
  • -48726-TM-
  • -Crk_SH3-
  • -Crk_SH3-ErkDD-
Kirrel
Kirrel3 		ENSDARP00000025881
ENSDARP00000045398 		ENSDARG00000001634
ENSDARG00000019473
ENSDARG00000056998
  • -I-set-C2-set_2-I-set-I-set-TM-
  • -I-set-C2-set_2-I-set-I-set-TM-
  • -48726-48726-48726-48726-TM-
  • -48726-48726-48726-48726-TM-
  • -ErkDD-Grb2_SH2-p38_Kin-PDZ_class1-
  • -Grb2_SH2-1433_m1-p38_Kin-PDZ_class1-
Nitr14b ENSDARP00000096297 ENSDARG00000071397
  • -V-set-
  • -48726-
  • -No hits-
Cadm4 ENSDARP00000058959 ENSDARG00000040291
  • -V-set-C2-set_2-ig-TM-
  • -48726-48726-48726-TM-
  • -PDZ_class2-
Nptn ENSDARP00000082663 ENSDARG00000019881
ENSDARG00000041023
ENSDARG00000043864
  • -ig-ig-I-set-TM-
  • -48726-48726-TM-
  • -No hits-
Sc:d0254 XP_001339787 XP_001339787
  • -TM-V-set-TM-
  • -TM-48726-48726-TM-
  • -PDZ_nNOS_1-
Cadm3 ENSDARP00000074048 ENSDARG00000009930
ENSDARG00000057013
ENSDARG00000062633
  • -C2-set_2-I-set-TM-
  • -48726-48726-TM-
  • -PDZ_class2-
Lrrc17 ENSDARP00000055316 ENSDARG00000037960
  • -No hits-
  • -52058-
  • -No hits-
Mpzl2
Mpzl3 		ENSDARP00000032601
ENSDARP00000089789 		ENSDARG00000027345
ENSDARG00000038609
ENSDARG00000059048
ENSDARG00000068454
  • -TM-V-set-TM-
  • -No hits-
  • -TM-48726-TM-
  • -No hits-
  • -No hits-
  • -No hits-
Jam2
Jam3 		ENSDARP00000076426
ENSDARP00000082979 		ENSDARG00000017320
ENSDARG00000058996
ENSDARG00000061794
ENSDARG00000063421
ENSDARG00000068114
  • -V-set-I-set-TM-
  • -ig-TM-
  • -48726-TM-
  • -48726-48726-TM-
  • -No hits-
  • -PDZ_class2-
Sc:d0220 ENSDARP00000096688 ENSDARG00000058537
ENSDARG00000060953
ENSDARG00000071576
ENSDARG00000071578
ENSDARG00000071588
ENSDARG00000071590
ENSDARG00000071647
ENSDARG00000071651
ENSDARG00000071653
  • -TM-V-set-TM-
  • -TM-48726-TM-
  • -ErkDD-PDZ_class1-
Dlc ENSDARP00000018643 ENSDARG00000002336
ENSDARG00000004232
ENSDARG00000010791
ENSDARG00000020219
ENSDARG00000070425
  • -MNNL-DSL-EGF_2-EGF-EGF-EGF-EGF-EGF-EGF-EGF-TM-
  • -57196-57196-57196-57196-57196-TM-
  • -PDZ_class1-
Neo1 ENSDARP00000004654 ENSDARG00000008937
ENSDARG00000018556
  • -I-set-ig-I-set-I-set-fn3-fn3-fn3-fn3-fn3-fn3-Neogenin_C-TM-
  • -48726-48726-48726-49265-49265-49265-49265-49265-49265-TM-
  • -PKA_Kin-GSK3_Kin-
Fgfrl1a
Fgfrl1b 		ENSDARP00000077102
ENSDARP00000068917 		ENSDARG00000032617
ENSDARG00000052556
  • -I-set-I-set-I-set-TM-
  • -I-set-I-set-I-set-TM-
  • -48726-48726-TM-
  • -48726-48726-TM-
  • -No hits-
  • -ErkDD-
Sc:d0179 NP_001091724 NP_001091724
  • -TM-
  • -48726-TM-
  • -No hits-
Pdgfrl ENSDARP00000024039 ENSDARG00000006456
ENSDARG00000071561
  • -ig-ig-
  • -48726-
  • -No hits-
Zgc:77222 ENSDARP00000056137 ENSDARG00000014323
ENSDARG00000038467
ENSDARG00000059229
ENSDARG00000063659
  • -TM-V-set-
  • -TM-48726-
  • -No hits-
Igfbp7 ENSDARP00000012597 ENSDARG00000005943
ENSDARG00000010925
ENSDARG00000014907
ENSDARG00000017389
ENSDARG00000032831
ENSDARG00000043385
ENSDARG00000052895
ENSDARG00000053509
ENSDARG00000055947
ENSDARG00000059135
ENSDARG00000068656
ENSDARG00000068667
ENSDARG00000068795
ENSDARG00000068800
ENSDARG00000068810
ENSDARG00000068819
ENSDARG00000069845
ENSDARG00000069854
ENSDARG00000069858
ENSDARG00000069862
ENSDARG00000069877
ENSDARG00000069882
ENSDARG00000069885
ENSDARG00000069889
ENSDARG00000069896
ENSDARG00000069903
ENSDARG00000069908
ENSDARG00000069909
ENSDARG00000069911
ENSDARG00000069921
ENSDARG00000070136
ENSDARG00000070138
ENSDARG00000070139
  • -Kazal_2-I-set-
  • -100895-48726-
  • -No hits-
Sid4 ENSDARP00000090925 ENSDARG00000034273
  • -I-set-I-set-I-set-I-set-
  • -48726-48726-48726-
  • -No hits-
Pvrl3l ENSDARP00000028921 ENSDARG00000006604
ENSDARG00000057399
  • -TM-V-set-C2-set_2-ig-TM-
  • -TM-48726-48726-48726-TM-
  • -No hits-
Boc NP_001005393 NP_001005393
  • -ig-V-set-I-set-I-set-fn3-fn3-fn3-TM-
  • -48726-48726-48726-49265-49265-49265-TM-
  • -No hits-
Cntfr ENSDARP00000034163 ENSDARG00000006368
ENSDARG00000024365
ENSDARG00000026736
ENSDARG00000028661
ENSDARG00000030498
ENSDARG00000042903
ENSDARG00000042909
ENSDARG00000045959
ENSDARG00000053620
ENSDARG00000070398
  • -TM-
  • -TM-48726-49265-
  • -ErkDD-1433_m1-Grb2_SH2-PDZ_class1-
Igsf21b ENSDARP00000094963 ENSDARG00000031049
ENSDARG00000056084
  • -V-set-
  • -48726-
  • -No hits-
Musk_sv1
Musk 		ENSDARP00000028386
ENSDARP00000064921 		ENSDARG00000000102
  • -I-set-I-set-ig-Fz-Kringle-TM-Pkinase_Tyr-TM-
  • -I-set-I-set-I-set-Fz-Kringle-TM-Pkinase_Tyr-TM-
  • -48726-48726-57440-TM-56112-TM-
  • -48726-48726-57440-TM-56112-TM-
  • -No hits-
  • -No hits-
Pvrl2l ENSDARP00000087041 ENSDARG00000062831
ENSDARG00000063390
  • -V-set-C2-set_2-ig-TM-
  • -48726-48726-48726-TM-
  • -No hits-
Kdrl ENSDARP00000007209 ENSDARG00000015815
ENSDARG00000019371
  • -ig-I-set-Pkinase_Tyr-
  • -48726-48726-48726-48726-48726-48726-56112-
  • -No hits-
Bcan ENSDARP00000094149 ENSDARG00000016736
  • -V-set-Xlink-Xlink-
  • -48726-56436-56436-
  • -No hits-
Cntn1a NP_851300 ENSDARG00000045685
ENSDARG00000070384
NP_851300
  • -ig-I-set-I-set-I-set-ig-fn3-fn3-fn3-
  • -48726-48726-48726-48726-49265-49265-49265-49265-
  • -No hits-
Mxra8a ENSDARP00000084146 ENSDARG00000062129
ENSDARG00000062222
  • -V-set-V-set-TM-
  • -48726-48726-TM-
  • -PKC_epsilon-
Zgc:92647 ENSDARP00000058773 ENSDARG00000040178
  • -V-set-
  • -48726-
  • -No hits-
Zgc:158817 ENSDARP00000036626 ENSDARG00000004131
ENSDARG00000045391
  • -V-set-V-set-TM-
  • -48726-48726-TM-
  • -ErkDD-
Sc:d0647 OTTDARP00000009362 OTTDARP00000009362
  • -I-set-ig-TM-
  • -48726-48726-TM-
  • -No hits-
Zgc:123297 ENSDARP00000073808 ENSDARG00000004109
ENSDARG00000029111
ENSDARG00000039257
ENSDARG00000056798
  • -V-set-TM-
  • -48726-48726-TM-
  • -No hits-
Cadm1b XP_690673 XP_690673
  • -V-set-C2-set_2-ig-TM-
  • -48726-48726-TM-
  • -PDZ_class2-
Pdgfra ENSDARP00000000960 ENSDARG00000030379
ENSDARG00000070494
  • -ig-TM-Pkinase_Tyr-TM-
  • -48726-48726-48726-TM-56112-TM-
  • -No hits-
Appb
Appa 		NP_690842
ENSDARP00000075913 		ENSDARG00000026738
ENSDARG00000054864
ENSDARG00000055543
ENSDARG00000059036
NP_690842
  • -A4_EXTRA-Beta-APP-TM-
  • -No hits-
  • -56491-89811-109843-TM-
  • -109843-
  • -ErkDD-Abl_SH2-Shc_PTB-
  • -No hits-
Ntn1b ENSDARP00000038885 ENSDARG00000022531
ENSDARG00000033733
ENSDARG00000036422
  • -Laminin_N-Laminin_EGF-Laminin_EGF-Laminin_EGF-NTR-
  • -57196-57196-50242-
  • -No hits-
Slit1b
Slit2
Slit3 		ENSDARP00000041465
ENSDARP00000093354
ENSDARP00000046111 		ENSDARG00000004246
ENSDARG00000034268
ENSDARG00000039528
ENSDARG00000044954
  • -LRRNT-LRRCT-LRRNT-LRR_1-LRRNT-EGF-EGF-EGF-EGF-EGF-EGF-Laminin_G_2-EGF-EGF-EGF-
  • -TM-LRRNT-LRRCT-LRRNT-LRR_1-LRRCT-LRRNT-LRRCT-LRRNT-LRRCT-EGF-EGF-EGF-EGF-EGF-EGF-Laminin_G_2-
  • -LRRNT-LRR_1-LRRCT-LRRNT-LRRCT-LRRNT-LRRCT-LRRNT-LRR_1-LRRCT-EGF-EGF-EGF-EGF-EGF-EGF-Laminin_G_2-EGF-
  • -52058-57196-49899-57196-57196-
  • -TM-52058-49899-52058-57196-57196-57196-57196-57196-
  • -52058-52058-57196-49899-57196-57196-57196-
  • -No hits-
  • -No hits-
  • -No hits-
Nadl1.2 ENSDARP00000005473 ENSDARG00000007149
ENSDARG00000015025
  • -I-set-I-set-I-set-I-set-ig-fn3-fn3-fn3-fn3-fn3-TM-
  • -48726-48726-48726-48726-48726-49265-49265-49265-49265-49265-TM-
  • -DNA_PK-
Lgi1a ENSDARP00000027521 ENSDARG00000020493
ENSDARG00000037243
ENSDARG00000041358
ENSDARG00000058421
ENSDARG00000069701
ENSDARG00000070018
  • -EPTP-
  • -50969-52058-
  • -No hits-
* quick link - http://q.sanger.ac.uk/7a8xql7a