Databases

Genomic research generates data on a massive scale and methods to manage and interpret large-scale data are essential to translation of research into biological understanding.

The Wellcome Trust Sanger Institute has developed - often with colleagues outside the institute - a suite of databases to help researchers. These can be accessed from this page.

[Wellcome Library, London]

ARNIE

ARNIEAVEXIS Receptor Network with Integrated Expression

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COSMIC

COSMICDatabase of somatic mutation information in human cancers

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ENCODE

ENCODEAims to identify all functional elements in the human genome sequence

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Ensembl Genome Browser

Ensembl Genome BrowserEnsembl produces and maintains automatic annotation on selected eukaryotic genomes

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Exomiser

ExomiserAnnotates, filters and prioritises Exome sequencing variants

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GLIDERS

GLIDERSGenome-wide linkage disequilibrium repository and search engine

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Pfam

PfamProvides a classification of proteins into families and domains using hidden Markov models

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PhenoDigm

PhenoDigmPrioritising disease gene candidates by semantically comparing phenotypes of human diseases and animal models

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Tiffin

TiffinA database of predicted regulatory motifs, a subset with predicted functional annotation

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VEGA Genome Browser

VEGA Genome BrowserCentral database repository for high quality manual annotation of vertebrate finished genome sequence

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BLAST

BLASTThe sequencing projects' Blast Search Services

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DECIPHER

DECIPHERDecipher functionality includes deposition and analysis of sequence variants in addition to data interpretation and matchmaking

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GeneDB

GeneDBAnnotation from a growing number of organisms is available from the GeneDB web database

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MEROPS

MEROPSProvides the internationally recognised classification of peptidases and their inhibitors

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Rfam

RfamProvides a classification of RNA families using covariance models

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TreeFam

TreeFamProvides curated phylogenetic trees of animal genes, that give reliable ortholog and paralog assignments

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Wormbase

WormbaseThe primary database on the biology and genome of the model organism Caenorhabditis elegans

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ZF-Models

ZF-ModelsUse of zebrafish to make models for human disease and development

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* quick link - http://q.sanger.ac.uk/7qsyuivy