Staff PhD and MPhil theses - Wellcome Trust Sanger Institute

Staff PhD and MPhil theses in pdf format

Staff PhD theses can be download here. The first link goes to a directory containing a set of PDF files of the thesis, the second a compressed TAR file of these pdfs.

PhD Theses
MPhil Theses

PhD Theses

Identification and Characterisation of Regulatory Elements on Human Chromosome 20q12-13.2
Akan, Pelin (2006)
- Pelin Akan's thesis
- tar.gz file
Studies of the effects of promoter sequence variation on gene expression in human chromosome 22
Bacha, Jamil (2006)
- Jamil Bacha's thesis
- tar.gz file
Gene identification and characterisation on the human X chromosome
Barrett, Ian (2004)
- Ian Barrett's thesis
- tar.gz file
Survey of RNA editing in the human brain
Blow, Matthew J (2004)
- Matthew J Blow's thesis
- tar.gz file
Development of computational methods for analysing proteomic data for genome annotation
Brosch, Markus (2009)
- Markus Brosch's thesis
- tar.gz file
Mechanisms of change in protein architecture
Buljan, Marija (2010)
- Marija Buljan's thesis
- tar.gz file
Rearrangement breakpoints and viral integration sites in the human genome
Burford, Deborah (2007)
- Deborah Burford's thesis
- tar.gz file
Genetics of the anticoagulant drug warfarin
Chen, Yen-Yu (Leslie) (2007)
- Yen-Yu (Leslie) Chen's thesis
- tar.gz file
Protein Domains: New methods for detection and evolutionary analysis
Coin, Lachlan (2005)
- Lachlan Coin's thesis
- tar.gz file
Role of Synapse-Associated Protein 102 in Postsynaptic Signalling, Synaptic Plasticity and Learning
Cuthbert, Peter (2005)
- Peter Cuthbert's thesis
- tar.gz file
Generation of a murine ES cell system deficient in microRNA processing for the identification of microRNA targets
Davis, Matthew (2009)
- Matthew Davis' thesis
- tar.gz file
The SCL Gene and Transcriptional Control of Haematopoiesis
Dhami, Pawandeep (2005)
- Pawandeep Dhami's thesis
- tar.gz file
Development of Chromatin Immuniprecipitation Microarray Technology for the Identification of Regulatory Elements in the Human Genome
Dillon, Shane (2008)
- Shane Dillon's thesis
- tar.gz file
The role of regulatory variation in sculpting gene expression across human populations and cell types
Dimas, Antigone (2009)
- Antigone Dimas' thesis
- tar.gz file
Motif based computational identification of protein subcellular localisation
Dogruel, Mutlu (2008)
- Mutlu Dogruel's thesis
- tar.gz file
Computational localization of promoters and transcription start sites in mammalian genomes
Down, Thomas (2003)
- Thomas Down's thesis
- tar.gz file
Studies on the development and organisation of the nervous system of Caenorhabditis elegans
Durbin, Richard (1987)
- Richard Durbin's thesis
- tar.gz file
An Analysis of Transcript Variation in Human Xp11.23
Eades, Tamsin L (2005)
- Tamsin L Eades' thesis
- tar.gz file
Genetic Studies of Syndromes of Severe Insulin Resistance and Type 2 Diabetes: a candidate gene approach
Fawcett, Katherine (2008)
- Katherine Fawcett's thesis
- tar.gz file
Structural, functional and comparative studies of human chromosome 22q13.31
Goward, Melanie (2002)
- Melanie Goward's thesis
- tar.gz file
Chromosome 1 map, sequence and variation
Gregory, Simon (2003)
- Simon Gregory's thesis
- tar.gz file
Recessive genetic screen for mismatch repair components in BLM-deficient ES cells
Guo, Ge (2004)
- Ge Guo's thesis
- tar.gz file
Computational Detection and Analysis of Polyadenylation Signals
Hajarnavis, Ashwin (2005)
- Ashwin Hajarnavis' thesis
- tar.gz file
Phenotypic and Functional Characterisation of Innate and Adaptive Immune Responses after Mucosal Vaccination
Hall, Lindsay (2007)
- Lindsay Hall's thesis
- tar.gz file
Prediction and analysis of nucleosome positioning in genomic sequences
Hasan, Samiul (2003)
- Samiul Hasan's thesis
- tar.gz file
Studies in probabilistic sequence alignment and evolution
Holmes, Ian (1998)
- Ian Holmes' thesis
- tar.gz file
Genomic variation and evolution of Salmonella enterica serovars Typhi and Paratyphi A
Holt, Kathryn (2009)
- Kathryn Holt's thesis
- tar.gz file
Gene predication using a configurable system for the integration of data by Dynamic programming
Howe, Kevin (2003)
- Kevin Howe's thesis
- tar.gz file
Physical, transcriptional and comparative mapping on the human X chromosome
Howell, Gareth (2002)
- Gareth Howell's thesis
- tar.gz file
Computational detection of non-coding RNAs in genomes
Huang, Yen-Hua (2008)
- Yen-Hua Huang's thesis
- tar.gz file
Characterization of Cancer Gene Mutations in Human Cancer Cell lines for Correlation with Drug Activity
Ikediobi, Ogechi (2008)
- Ogechi Ikediobi's thesis
- tar.gz file
Identification of target genes of an erythroid transcription factor complex containing SCL(TAL1)
Jim, Hau Ling (2008)
- Hau Ling Jim's thesis
- tar.gz file
A role for microRNA-155 in the control of infection
John, Victoria (2010)
- Victoria John's thesis
- tar.gz file
Identification of Genetic Differences Between Strains of Campylobacter jejuni
Kay, Emily (2005)
- Emily Kay's thesis
- tar.gz file
Investigations into the Rab family of genes and their roles in signalling during vertebrate early development
Kenyon, Emma (2006)
- Emma Kenyon's thesis
- tar.gz file
Transposon-mediated Insertional Mutagenesis in Gene Discovery and Cancer
Kong, Jun (2011)
- Jun Kong's thesis
- tar.gz file
Genome-Wide Translational Control In Fission Yeast
Lackner, Daniel (2007)
- Daniel Lackner's thesis
- tar.gz file
Karyotype Evolution: Evolutionary Chromosome Rearrangements in Material Homologous to Human Chromosome 22q Studied in the Dog and Gibbon
Langford, Cordelia (2003)
- Cordelia Langford's thesis
- tar.gz file
Metabolic capability in host-restricted serovars of Salmonella enterica
Langridge, Gemma C (2010)
- Gemma C Langridge's thesis
- tar.gz file
Characterisation of bcl11 functions in development using genetically modified mice
Lee, Song Choon (2008)
- Song Choon Lee's thesis
- tar.gz file
A recessive genetic screen to discover components in miRNA pathways using piggyBac-mediated insertional mutagenesis in Blm-deficient mouse embryonic stem cells
Li, Meng (2010)
- Meng Li's thesis
- tar.gz file
Reprogramming of T cells to natural killer-like cells upon BCL11B deletion
Li, Peng (2010)
- Peng Li's thesis
- tar.gz file
Evolutionary Landscape of CpG Island Methylation in X Chromosome Inactivation
Liu, Mengning (2008)
- Mengning Liu's thesis
- tar.gz file
Identification and Functional Characterisation of a Genetic Subset of Non-Small Cell Lung Cancer
Mahoney, Claire (2009)
- Claire Mahoney's thesis
- tar.gz file
The role of microRNAs in neurons - (Also known as Sergei A Manakov)
Manakou, Siarhei (2011)
- Siarhei Manakou's thesis
- tar.gz file
Mathematical methods for comparative ab initio gene prediction
Meyer, Imtraud (2002)
- Imtraud Meyer's thesis
- tar.gz file
Analysis of genetic variation data using Ancestral Recombination Graphs
Minichiello, Mark (2007)
- Mark Minichiello's thesis
- tar.gz file
Evolution and gene regulation of the genomic imprinting mechanism
Mungall, Andy (2007)
- Andy Mungall's thesis
- tar.gz file
Analysis of the transcriptomes of wild-type and mutant C. elegans
Nelson, Andrew (2008)
- Andrew Nelson's thesis
- tar.gz file
Regulatory variation and its role in disease
Nica, Alexandra C (2010)
- Alexandra C Nica's thesis
- tar.gz file
Genetic mapping of cellular traits
Parts, Leopold (2011)
- Leopold Parts' thesis
- tar.gz file
Characterisation of the Transcriptome and Proteome of Salmonella enterica subspecies enterica serovar Typhi
Perkins, Timothy (2009)
- Timothy Perkins' thesis
- tar.gz file
Isolation of homozygous mutant mouse embryonic stem cells by selection for copy number increase
Pettitt, Stephen J (2011)
- Stephen J Pettitt's thesis
- tar.gz file
Analysis of IncHI1 plasmids in Salmonella enterica serovar Typhi
Phan, Minh-Duy (2009)
- Minh-Duy Phan's thesis
- tar.gz file
Inference and classification of eukaryotic cis-regulatory motifs
Piipari, Matias (2010)
- Matias Piipari's thesis
- tar.gz file
Computational Analysis of Genomes
Pocock, Matthew R (2003)
- Matthew R Pocock's thesis
- tar.gz file
The Zebrafish Homologues of JAM-B and JAM-C are Essential for Myoblast Fusion
Powell, Gareth T (2010)
- Gareth T Powell's thesis
- tar.gz file
Computational detection of gene regulatory signals in human genome sequence
Ramadass, Aroul S (2004)
- Aroul S Ramadass' thesis
- tar.gz file
Genome Evolution: A study of MHC paralogous genes in the human genome
Rand, Vikki (2003)
- Vikki Rand's thesis
- tar.gz file
Murine embryonic stem cells as a route towards exploring host-pathogen interactions
Rossi, Raffaella (2008)
- Raffaella Rossi's thesis
- tar.gz file
Periodic gene expression program of the fission yeast cell cycle
Rustici, Gabriella (2004)
- Gabriella Rustici's thesis
- tar.gz file
The role of protein interactions in evolution and disease
Schuster-Bockler, Benjamin (2008)
- Benjamin Schuster-Bockler's thesis
- tar.gz file
The role of the CapZ complex in vertebrate sarcomere integrity
Scott, Annabelle (2007)
- Annabelle Scott's thesis
- tar.gz file
Human chromosome 20q12-13.2: Structural, comparative and sequence variation studies
Stavrides, George (2002)
- George Stavrides' thesis
- tar.gz file
Methods for genome-scale gene perturbation studies of the TRAIL-induced apoptosis pathway in mammalian cell culture
Sudbery, Ian (2007)
- Ian Sudbery's thesis
- tar.gz file
Copy Number Variation and Schizophrenia
Tam, Gloria Wing Chi (2008)
- Gloria Wing Chi Tam's thesis
- tar.gz file
Molecular characterisation of the candidate region for bronx waltzer: a mouse model of hearing impairment
Taylor, Amy (2005)
- Amy Taylor's thesis
- tar.gz file
Analysis of genes controlling notochord development in zebrafish
Thomas, Kevin (2005)
- Kevin Thomas' thesis
- tar.gz file
Characterization of a Novel Deletion Allele of Brca1
Thompson, Debrah M (2003)
- Debrah M Thompson's thesis
- tar.gz file
Systematic Analysis of the Evolution and Conservation of Genetic Interactions Using C. elegans as a Model System
Tischler, Julia (2007)
- Julia Tischler's thesis
- tar.gz file
Identification and Characterisation of Differentially Methylated Regions within the human Major Histocompatibility Complex
Tomazou, Eleni M (2008)
- Eleni M Tomazou's thesis
- tar.gz file
In silico prediction of Genomic In Islands in microbial genomes Islands
Vernikos, George (2008)
- George Vernikos' thesis
- tar.gz file
Chromosome-specific Recessive Genetic Screen for Genes Involved in In Vitro Differentiation in Mouse Embyonic Stem Cells
Wang, Wei (2005)
- Wei Wang's thesis
- tar.gz file
Application of DNA Microarrays to Assess DNA Replication Timing and Chromosomal Aberrations
Woodfine, Kathryn (2003)
- Kathryn Woodfine's thesis
- tar.gz file
Genome-wide recessive screens for DNA mismatch repair genes in mouse ES cells
Xiong, Zikai (2008)
- Zikai Xiong's thesis
- tar.gz file
Biological Investigations through sequence analysis
Yeats, Corin (2004)
- Corin Yeats' thesis
- tar.gz file
Evolution by Gene Loss?
Yngvadottir, Bryndis (2008)
- Bryndis Yngvadottir's thesis
- tar.gz file
Identification and analysis of MHC-linked olfactory receptor genes
Younger, Ruth (2002)
- Ruth Younger's thesis
- tar.gz file

MPhil Theses

Development of a Resource for the Exploration of Gene Expression in the Mouse Foetus
Campbell, Elizabeth A (2004)
- Elizabeth A Campbell's thesis
- tar.gz file
The relationship of identity by state to identity by descent and imputation accuracy in population sequencing data
Harris, Kelley (2011)
- Kelley Harris' thesis
- tar.gz file
Phenotypic variation in erythrocyte invasion by Plasmodium falciparum isolates from Peru
Hesketh, Richard (2011)
- Richard Hesketh's thesis
- tar.gz file
Overexpression of Mammalian Nanog mRNA Hyperdorsalises Zebrafish Embryos
Jiang, Ying (2011)
- Ying Jiang's thesis
- tar.gz file
Bioinformatics approaches to RNA splicing
Levine, Aaron (2001)
- Aaron Levine's thesis
- tar.gz file
Bioinformatic Analysis of Imprinted CpG Islands in Mus musculus
Riordan, Daniel (2003)
- Daniel Riordan's thesis
- tar.gz file