Lu’s research interest is protein and peptide analysis using multi-dimensional HPLC and nanoLC-MS/MS methods, including protein identification and characterisation, protein post-translational modifications such as phosphorylation, palmitoylation and ubiquitination, and protein quantification. In addition, she also supports bioinformatics development in the team for efficient data mining and result generation. Due to the various collaborations both internally and externally, she also gives training to students, post-doctors and visiting scientists about MS sample preparation and data processing skills.
A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases.
Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.
BMC genomics 2014;15;160
Quantitative RNA-seq analysis of the Campylobacter jejuni transcriptome.
Microbiology (Reading, England) 2011;157;Pt 10;2922-32
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.
Cell stem cell 2010;6;4;382-95
Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores.
Journal of bacteriology 2009;191;17;5377-86
Accurate and sensitive peptide identification with Mascot Percolator.
Journal of proteome research 2009;8;6;3176-81
Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence disorder.
Molecular & cellular proteomics : MCP 2008;7;7;1331-48
Proteomic analysis of in vivo phosphorylated synaptic proteins.
The Journal of biological chemistry 2005;280;7;5972-82
The three-dimensional structure and X-ray sequence reveal that trichomaglin is a novel S-like ribonuclease.
Structure (London, England : 1993) 2004;12;6;1015-25
Epitope mapping of monoclonal antibodies by mass spectrometry: identification of protein antigens in complex biological systems.
Journal of the American Society for Mass Spectrometry 1998;9;3;208-15