My main research interests lie in how genetic variation influences transcriptional regulation and gene expression programs.
To fulfil this goal I am currently in the group of Professor Nicole Soranzo. Here we study the effects and consequences of genetic variation on epigenetic and transcriptional regulation at a population level. Using immune cells as our model, I am primarily involved in large scale data acquisition and analysis of ChIP-seq experiments for transcription factors essential to myeloid cell function.
AHT-ChIP-seq: a completely automated robotic protocol for high-throughput chromatin immunoprecipitation.
Genome biology 2013;14;11;R124
Rapid turnover of long noncoding RNAs and the evolution of gene expression.
PLoS genetics 2012;8;7;e1002841
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.
Genome research 2012;22;11;2163-75
A coordinated global control over cellular transcription.
Current biology : CB 2010;20;22;2010-5
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
urg1: a uracil-regulatable promoter system for fission yeast with short induction and repression times.
PloS one 2008;3;1;e1428