Louella Judy Vasquez, PhD | Staff Scientist

Vasquez, Louella Judy

Louella is a bioinformatician working on high dimensional genomics data such as RNA-, ChiP- sequencing and DNA methylation. She is interested in how genetic variation affects the transcriptional and epigenetic landscapes that mark cellular identity. She wants to gain an in depth understanding of the biology of stem cell differentiation using blood as a model system. She is currently working on the Blueprint project and genomic characterisations of novel blood cells derived from human stem cells.

Publications

  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

    Chen L, Ge B, Casale FP, Vasquez L, Kwan T et al.

    Cell 2016;167;5;1398-1414.e24

  • The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

    Astle WJ, Elding H, Jiang T, Allen D, Ruklisa D et al.

    Cell 2016;167;5;1415-1429.e19

  • Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

    Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y et al.

    Nature communications 2016;7;11208

  • From GWAS to function: lessons from blood cells.

    Vasquez LJ, Mann AL, Chen L and Soranzo N

    ISBT science series 2016;11;Suppl Suppl 1;211-219

  • JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia.

    Hobbs CM, Manning H, Bennett C, Vasquez L, Severin S et al.

    Blood 2013;122;23;3787-97

  • Transcriptional diversity during lineage commitment of human blood progenitors.

    Chen L, Kostadima M, Martens JHA, Canu G, Garcia SP et al.

    Science (New York, N.Y.) 2014;345;6204;1251033

Vasquez, Louella Judy
Louella's Timeline
2016

Staff Scientist, Wellcome Trust Sanger Institute

2012

Postdoctoral Fellow, Wellcome Trust Sanger Institute

2010

PhD Physics, University of Warwick

Junior Research Fellow, Centre for Complexity Science and Department of Statistics, University of Warwick

2006

MSc Physics, University of the Philippines

2003

BSc Physics, University of the Philippines