Vasquez, Louella Judy
Louella is a bioinformatician working on high dimensional genomics data such as RNA-, ChiP- sequencing and DNA methylation. She is interested in how genetic variation affects the transcriptional and epigenetic landscapes that mark cellular identity. She wants to gain an in depth understanding of the biology of stem cell differentiation using blood as a model system. She is currently working on the Blueprint project and genomic characterisations of novel blood cells derived from human stem cells.
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.
Nature communications 2016;7;11208
From GWAS to function: lessons from blood cells.
ISBT science series 2016;11;Suppl Suppl 1;211-219
JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia.
Transcriptional diversity during lineage commitment of human blood progenitors.
Science (New York, N.Y.) 2014;345;6204;1251033