James is a programmer with the Genome Reference Informatics Team. His work includes genome assembly and analysis, communications with external collaborators, and the creation and maintenance of web-based tools.
The zebrafish reference genome sequence and its relationship to the human genome.
Modernizing reference genome assemblies.
PLoS biology 2011;9;7;e1001091
The geometry of interactions between catalytic residues and their substrates.
Journal of molecular biology 2007;369;4;1140-52
Evolution of binding sites for zinc and calcium ions playing structural roles.
Using a library of structural templates to recognise catalytic sites and explore their evolution in homologous families.
Journal of molecular biology 2005;347;3;565-81
MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms.
Nucleic acids research 2007;35;Database issue;D515-20