Laura O'Neill | Scientific Manager

O'Neill, Laura

Laura coordinates the reception, QC and sequencing of samples within the Cancer Faculty, supervising procedures and processes, to ensure a smooth and efficient progression of all its associated projects.

Publications

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer.

    Campbell PJ, Yachida S, Mudie LJ, Stephens PJ, Pleasance ED et al.

    Nature 2010;467;7319;1109-13

  • Somatic structural rearrangements in genetically engineered mouse mammary tumors.

    Varela I, Klijn C, Stephens PJ, Mudie LJ, Stebbings L et al.

    Genome biology 2010;11;10;R100

  • Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors.

    McBride DJ, Orpana AK, Sotiriou C, Joensuu H, Stephens PJ et al.

    Genes, chromosomes & cancer 2010;49;11;1062-9

  • Massive genomic rearrangement acquired in a single catastrophic event during cancer development.

    Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR et al.

    Cell 2011;144;1;27-40

  • Mutational processes molding the genomes of 21 breast cancers.

    Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD et al.

    Cell 2012;149;5;979-93

  • Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.

    Tarpey PS, Behjati S, Cooke SL, Van Loo P, Wedge DC et al.

    Nature genetics 2013;45;8;923-6

  • Recurrent PTPRB and PLCG1 mutations in angiosarcoma.

    Behjati S, Tarpey PS, Sheldon H, Martincorena I, Van Loo P et al.

    Nature genetics 2014;46;4;376-379

  • Processed pseudogenes acquired somatically during cancer development.

    Cooke SL, Shlien A, Marshall J, Pipinikas CP, Martincorena I et al.

    Nature communications 2014;5;3644

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing.

    Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G et al.

    Nature medicine 2015;21;7;751-9

O\'Neill, Laura
Laura's Timeline
2016

Scientific Manager, Cancer, Ageing and Somatic Mutations programme, Sanger Institute

2011

Senior Research Assistant, Cancer Genome Project, Sanger Institute

2009

Advanced Research Assistant, Cancer Genome Project, Sanger Institute

2008

Research Assistant, Cancer Genome Project, Sanger Institute

2007

BSc [Hons] Biochemistry, University of Birmingham