Jyoti is a CRUK Clinician Scientist and Consultant Haematologist. She utilises sequencing technologies to help understand why blood cancers originate and evolve, and how this relates to normal development and ageing.
Pathogenesis of Myeloproliferative Disorders.
Annual review of pathology 2016;11;101-26
DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype.
Effect of mutation order on myeloproliferative neoplasms.
The New England journal of medicine 2015;372;7;601-612
MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling.
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
The New England journal of medicine 2013;369;25;2391-2405