I am an evolutionary biologist and genomic data scientist, broadly interested in the epidemiology and population genomics of major pathogens, particularly in the context of the dissemination and emergence of antimicrobial resistance. Furthermore, I developed mathematical and simulation frameworks to elucidate complex evolutionary dynamics of microbial populations during adaptation and the impact of recombination on adaptation.
The dissemination of multidrug-resistant Enterobacter cloacae throughout the UK and Ireland.
Nature microbiology 2016;1;16173
Recent independent emergence of multiple multidrug-resistant Serratia marcescens clones within the United Kingdom and Ireland.
Genome research 2016;26;8;1101-9
Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland.
Evolution of the Staphylococcus argenteus ST2250 Clone in Northeastern Thailand Is Linked with the Acquisition of Livestock-Associated Staphylococcal Genes.
The evolution of natural competence: disentangling costs and benefits of sex in bacteria.
The American naturalist 2013;182;4;E112-26
Recombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1.
PLoS genetics 2014;10;6;e1004439
The effect of bacterial recombination on adaptation on fitness landscapes with limited peak accessibility.
PLoS computational biology 2012;8;10;e1002735
The impact of natural transformation on adaptation in spatially structured bacterial populations.
BMC evolutionary biology 2014;14;141
Population structure of multidrug resistant Klebsiella oxytoca within hospitals across the UK and Ireland identifies sharing of virulence and resistance genes with K. pneumoniae.
Genome biology and evolution 2017
Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae.
Genome medicine 2017;9;1;6