Dr Natsuhiko Kumasaka | Staff Scientist

Kumasaka, Natsuhiko

I aim to understand biological phenomena through mathematical/statistical modeling. Currently I'm working on a novel statistical approach that uses a pairwise hierarchical model incorporating a Mendelian Randomisation technique to map causal regulatory interactions in the human genome.


  • Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.

    Kumasaka N, Knights AJ and Gaffney DJ

    Nature genetics 2016;48;2;206-13

  • Genetic background drives transcriptional variation in human induced pluripotent stem cells.

    Rouhani F, Kumasaka N, de Brito MC, Bradley A, Vallier L and Gaffney D

    PLoS genetics 2014;10;6;e1004432

  • Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.

    Kumasaka N, Aoki M, Okada Y, Takahashi A, Ozaki K et al.

    PloS one 2012;7;9;e44507

  • PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.

    Kumasaka N, Fujisawa H, Hosono N, Okada Y, Takahashi A et al.

    Genetic epidemiology 2011;35;8;831-44

Kumasaka, Natsuhiko