Dr Ro (Rosemary) Kelsell | Project Administrator

Kelsell, Ro (Rosemary)

I am the project administrator for Deciphering Developmental Disorders (DDD). My duties include communication with the regional genetics services to help with the smooth running of the project and the co-ordination of data supply to over 120 complementary analysis projects.

Prior to joining the WTSI I worked as a computational biologist in the pharmaceutical industry where I also gained experience as a project manager in drug discovery. Prior to my time in industry I worked in academia on eye diseases, DNA repair and mutation mechanisms.

Publications

  • Identification of a novel 5-HT(4) receptor splice variant (r5-HT(4c1)) and preliminary characterisation of specific 5-HT(4a) and 5-HT(4b) receptor antibodies.

    Ray AM, Kelsell RE, Houp JA, Kelly FM, Medhurst AD et al.

    European journal of pharmacology 2009;604;1-3;1-11

  • Tissue distribution profiles of the human TRPM cation channel family.

    Fonfria E, Murdock PR, Cusdin FS, Benham CD, Kelsell RE and McNulty S

    Journal of receptor and signal transduction research 2006;26;3;159-78

  • TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

    Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P et al.

    Nature 2002;418;6894;186-90

  • Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy.

    Kelsell RE, Gregory-Evans K, Payne AM, Perrault I, Kaplan J et al.

    Human molecular genetics 1998;7;7;1179-84

  • Identification of a novel 5-HT(4) receptor splice variant (r5-HT(4c1)) and preliminary characterisation of specific 5-HT(4a) and 5-HT(4b) receptor antibodies.

    Ray AM, Kelsell RE, Houp JA, Kelly FM, Medhurst AD et al.

    European journal of pharmacology 2009;604;1-3;1-11

  • Tissue distribution profiles of the human TRPM cation channel family.

    Fonfria E, Murdock PR, Cusdin FS, Benham CD, Kelsell RE and McNulty S

    Journal of receptor and signal transduction research 2006;26;3;159-78

  • Genetic linkage analysis of a novel syndrome comprising North Carolina-like macular dystrophy and progressive sensorineural hearing loss.

    Francis PJ, Johnson S, Edmunds B, Kelsell RE, Sheridan E et al.

    The British journal of ophthalmology 2003;87;7;893-8

  • mRNA distribution analysis of human TRPC family in CNS and peripheral tissues.

    Riccio A, Medhurst AD, Mattei C, Kelsell RE, Calver AR et al.

    Brain research. Molecular brain research 2002;109;1-2;95-104

  • TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

    Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P et al.

    Nature 2002;418;6894;186-90

  • Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.

    Riccio A, Mattei C, Kelsell RE, Medhurst AD, Calver AR et al.

    The Journal of biological chemistry 2002;277;14;12302-9

  • Autosomal dominant cone-rod dystrophy with mutations in the guanylate cyclase 2D gene encoding retinal guanylate cyclase-1.

    Downes SM, Payne AM, Kelsell RE, Fitzke FW, Holder GE et al.

    Archives of ophthalmology (Chicago, Ill. : 1960) 2001;119;11;1667-73

  • The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK.

    Meadows HJ, Chapman CG, Duckworth DM, Kelsell RE, Murdock PR et al.

    Brain research 2001;892;1;94-101

  • Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery.

    Medhurst AD, Rennie G, Chapman CG, Meadows H, Duckworth MD et al.

    Brain research. Molecular brain research 2001;86;1-2;101-14

  • Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel.

    Chapman CG, Meadows HJ, Godden RJ, Campbell DA, Duckworth M et al.

    Brain research. Molecular brain research 2000;82;1-2;74-83

  • North Carolina macular dystrophy (MCDR1) locus: a fine resolution genetic map and haplotype analysis.

    Small KW, Udar N, Yelchits S, Klein R, Garcia C et al.

    Molecular vision 1999;5;38

  • Biochemical analysis of a dimerization domain mutation in RetGC-1 associated with dominant cone-rod dystrophy.

    Tucker CL, Woodcock SC, Kelsell RE, Ramamurthy V, Hunt DM and Hurley JB

    Proceedings of the National Academy of Sciences of the United States of America 1999;96;16;9039-44

  • Phenotype of a British North Carolina macular dystrophy family linked to chromosome 6q.

    Reichel MB, Kelsell RE, Fan J, Gregory CY, Evans K et al.

    The British journal of ophthalmology 1998;82;10;1162-8

  • A retGC-1 mutation in autosomal dominant cone-rod dystrophy.

    Perrault I, Rozet JM, Gerber S, Kelsell RE, Souied E et al.

    American journal of human genetics 1998;63;2;651-4

  • Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stargardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA), and North Carolina macular dystrophy (MCDR1).

    Gehrig A, Felbor U, Kelsell RE, Hunt DM, Maumenee IH and Weber BH

    Journal of medical genetics 1998;35;8;641-5

  • Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy.

    Kelsell RE, Gregory-Evans K, Payne AM, Perrault I, Kaplan J et al.

    Human molecular genetics 1998;7;7;1179-84

  • Localization of a gene (CORD7) for a dominant cone-rod dystrophy to chromosome 6q.

    Kelsell RE, Gregory-Evans K, Gregory-Evans CY, Holder GE, Jay MR et al.

    American journal of human genetics 1998;63;1;274-9

  • Localisation of a gene for dominant cone-rod dystrophy (CORD6) to chromosome 17p.

    Kelsell RE, Evans K, Gregory CY, Moore AT, Bird AC and Hunt DM

    Human molecular genetics 1997;6;4;597-600

Kelsell, Ro (Rosemary)
Ro (Rosemary)'s Timeline
2014

DDD project administrator, Wellcome Trust Sanger Institute Hinxton

2010

Consultant scientific ChEMBL database curator, EBI Hinxton

1999

Computational biologist, GlaxoSmithKline Harlow

1998

Clinical data coordinator, SmithKline Beecham Harlow

1995

Postdoctoral research fellow, Institute of Ophthalmology London

1992

Postdoctoral research fellow, DNA Repair Lab, University of Cambridge

PhD, Molecular analysis of high frequency deletions in a CHO cell line heterozygous for aprt, Imperial Cancer Research Fund, Clare Hall Labs

1985

Clinical cytogeneticist, Queen Elizabeth Hospital for Children London

BSc (Hons) Biology, University of Sussex