Deepti is a post-doctoral fellow in the Sandhu Group. Her current research focuses on characterising the genetic diversity among African populations and understanding their population history.
I trained as a clinician in internal medicine at Christian Medical College Vellore, India, following which I completed my PhD in genetic epidemiology at the University of Cambridge. I joined the Sanger Institute as a post-doctoral fellow in 2013.
My research focuses on characterising the genetic diversity among African populations, and understanding how this influences susceptibility to disease. I have a key interest in understanding the historical movements and mixing of populations that influenced the current genetic structure of these populations. My work involves analysis of dense genotype and whole genome sequences from diverse ethno-linguistic groups in Africa, including examination of ancient DNA from these regions. I am also interested in the development and application of new statistical methods to answer some of these questions.
The African Genome Variation Project shapes medical genetics in Africa.
A general approach for haplotype phasing across the full spectrum of relatedness.
PLoS genetics 2014;10;4;e1004234
Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians.
American journal of human genetics 2015;96;6;986-91
Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis.
International journal of epidemiology 2013;42;6;1754-71
A systematic review of definitions of extreme phenotypes of HIV control and progression.
AIDS (London, England) 2014;28;2;149-62
Discovery and refinement of loci associated with lipid levels.
Nature genetics 2013;45;11;1274-1283
Common variants associated with plasma triglycerides and risk for coronary artery disease.
Nature genetics 2013;45;11;1345-52
Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study.
Arteriosclerosis, thrombosis, and vascular biology 2012;32;12;3058-65