Dr Yoonha Choi | Postdoctoral Fellow

This person is a member of Sanger Institute Alumni.

Choi, Yoonha

I have interest in the developing and applying genetic screening tools into human iPSC. I’ve been focused on the validation of genetic modification methods for human iPSC in Sanger. Currently I'm using Cas9/CRISPR screening system to identify the regulation process for the definitive endodermal differentiation.

I'm working with human cell lines especially iPSC and ES for genome engineering. Also I have trained skill for the biochemical analysis especially for the protein kinase followed by its downstream pathways and phenotypic analysis of the mouse reproductive organs.


  • Defective folliculogenesis in female mice lacking Vaccinia-related kinase 1.

    Kim J, Choi YH, Chang S, Kim KT and Je JH

    Scientific reports 2012;2;468

  • HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence.

    Choi YH, Lim JK, Jeong MW and Kim KT

    Nucleic acids research 2012;40;17;8499-518

  • Vaccinia-related kinase 1 is required for the maintenance of undifferentiated spermatogonia in mouse male germ cells.

    Choi YH, Park CH, Kim W, Ling H, Kang A et al.

    PloS one 2010;5;12;e15254

  • Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

    Kang TH, Park DY, Choi YH, Kim KJ, Yoon HS and Kim KT

    Molecular and cellular biology 2007;27;24;8533-46

  • The orphan nuclear receptor SHP is involved in monocytic differentiation, and its expression is increased by c-Jun.

    Choi YH, Park MJ, Kim KW, Lee HC, Choi YH and Cheong J

    Journal of leukocyte biology 2004;76;5;1082-8

Career/Research Highlights

Choi, Yoonha
Yoonha's Timeline

PostDoc in Mouse genetics, Wellcome Trust Sanger Institute, UK


PostDoc in Life Science, Pohang University of Science and Technology (POSTECH), Korea


PhD in Life Science, Pohang University of Science and Technology (POSTECH), Korea


MS in Molecular biology, Pusan National Universty, Korea


BS in Psychology and Microbiology (Double major), Pusan National University, Korea