Sanger Institute's COSMIC database expands cancer cloud capabilities at the Institute for Systems Biology

The Institute for Systems Biology has embedded the COSMIC data within their Cancer Genomics Cloud (CGC), which is a cloud-based platform that uses Google BigQuery technology to bring unprecedented computing power to researchers around the world


The Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC) team announces a new agreement to provide their data to the U.S.-based Institute for Systems Biology (ISB).

COSMIC is an expert-curated cancer mutation database, and is the world’s largest and most comprehensive resource for exploring the impact of somatic mutations in human cancers.


With this agreement, the ISB have has embedded the COSMIC data within the ISB Cancer Genomics Cloud (CGC), which is a cloud-based platform that uses Google BigQuery technology to bring unprecedented computing power to researchers around the world.

Having COSMIC data within ISB-GCG (isb-cgc.org), which is funded by the National Institutes of Health’s National Cancer Institute, enables new types of cloud-based and cloud-powered analyses across a number of resources, including The Cancer Genome Atlas (TCGA).

COSMIC users can easily sign up via the COSMIC account page and documentation including examples is available to get people up and running quickly. 

“It is hugely exciting to be able to embed our carefully and manually curated COSMIC data within ISB-CGC. This enables scientists to study mutation trends at high resolution and perform integrative analyses of COSMIC and TCGA [The Cancer Genome Atlas] data using unparalleled computed power.” 

Dr. Simon Forbes, Head of COSMIC (Catalogue of Somatic Mutations)

“ISB [Institute for Systems Biology] has always valued open access to data. This agreement with COSMIC augments the ISB-CGC [ISB-Cancer Genomics Cloud] platform and makes it an even more useful resource for the cancer research community.”

Dr. Ilya Shmulevich, whose lab developed the ISB-CGC platform

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