Archive

8 Mar 2016

Sumana Sharma of the Wellcome Trust Sanger Institute and Robert Petryszak of the European Bioinformatics Institute (EMBL-EBI) have been recognised for their work to promote gender equality on the Wellcome Genome Campus

Mike Stratton, Ewan Birney and Rolf Apweiler today (8 March) acknowledged the contribution of two staff members to promoting gender equality in the life sciences, bestowing the second annual Sex in Science Best Practice Award on the Wellcome Genome Campus.

7 Mar 2016

A new computational approach in single-cell genomics reveals how different types of T cells detect, destroy and remember invaders.

Research from the Single-Cell Genomics Centre on the Wellcome Genome Campus could change the way we look at gene expression and immune response. Published in Nature Methods, the new method, TraCeR, provides a powerful tool for research into immune response, vaccination, cancer and autoimmunity.

25 Feb 2016

Genomic sequencing reveals link between STIs and leading cause of infectious blindness

For the first time, genome sequencing has been carried out on Chlamydia trachomatis (C. trachomatis), a bacteria responsible for the disease Trachoma - the world’s leading infectious cause of blindness, according to a study in Nature Communications.Researchers at the Wellcome Trust Sanger Institute and Menzies School of Health Research, Australia have discovered that genes can move from chlamydia strains in the eye to sexually transmitted strains of chlamydia, allowing them to then infect the eye and cause Trachoma – a neglected tropical disease.

25 Feb 2016

Researchers worked with Aboriginal Australian communities to explore heritage

The first complete sequences of the Y chromosomes of Aboriginal Australian men have revealed a deep indigenous genetic history tracing all the way back to the initial settlement of the continent 50 thousand years ago, according to a study published in the journal Current Biology.

16 Feb 2016

The bilharzia-causing parasite, Schistosoma mansoni,  first infected humans as they fished in lakes in East Africa and was spread, first to West Africa and then to the New World, by slave traders in 16th-19th Centuries, genomics reveals

Exploring the full DNA sequences of Schistosoma mansoni parasites from Africa and the French Caribbean has allowed scientists to map the origin of the human-infecting blood fluke, trace its historic transmission and identify the secrets of its success. The findings show how the global slave trade transported the disease from Senegal and Cameroon to Guadeloupe. Further genomic comparison with a closely related schistosome species that infects rodents has revealed how the parasite has adapted to infecting human beings.

8 Feb 2016

The Centre for Therapeutic Target Validation welcomes new member Biogen, expanding its efforts to accelerate drug discovery research

Biogen has joined the Centre for Therapeutic Target Validation (CTTV), the pioneering public-private collaboration to improve the success rate for discovering new medicines. Originally formed by GSK, the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EMBL-EBI), the CTTV fosters interactions between academic and industry members to select and validate novel targets in drug development.

19 Jan 2016

DNA from ancient British skeletons reveals immigrant history

For the first time, researchers have been able to directly estimate the Anglo-Saxon ancestry of the British population from ancient skeletons, showing how Anglo-Saxon immigrants mixed with the native population

11 Jan 2016

New protocol allows links between DNA methylation and gene expression to be studied in the same cells

A new single-cell genomics method to study links between DNA modifications (methylation) and the activity of a gene has been developed. This is the first method that allows scientists to study the epigenome and transcriptome of a single cell in parallel, helping researchers pinpoint the relationship between changes in DNA methylation and gene expression. 

18 Dec 2015

Cichlid fish from a tiny volcanic crater have been caught in the act of sympatric speciation

Can new species really evolve if there is no physical boundary to drive genetic separation? Physical and genomic evidence from the 700-metre wide volcanic crater Lake Massoko appears to have caught the process in the act

14 Dec 2015

Risk of having two children with the same genetic disorder is determined by mutation timing

Researchers compared mutation rates in sperm and eggs for multi-sibling families, confirming that fathers contribute more mutations to their children than mothers. They revealed for the first time that the rate at which mutations in sperm accumulate with age varies from father to father.

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