News Archive

News Archive

Acute myeloid leukaemia is at least 11 different diseases

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Acute myeloid leukaemia is at least 11 different diseases

Landmark study shows genetic changes explain differences in survival for young AML patients.

Ground-breaking study shows that Acute Myeloid Leukaemia (AML) is not a single disorder, but at least 11 different diseases, and that genetic changes explain differences in survival among young AML patients. Published in the New England Journal of Medicine, the largest study of its kind on the genetics of AML could improve clinical trials and the way patients are diagnosed and treated in the future.

Adrian Bird awarded 2016 Shaw Prize in Life Science and Medicine

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Adrian Bird awarded 2016 Shaw Prize in Life Science and Medicine

Associate Faculty member recognised for research into the genomics of autism spectrum disorder Rett Syndrome

The ‘Nobel of the East’ is awarded by the Hong Kong-based Shaw Prize Foundation, to honour recent breakthroughs by active researchers in the fields of mathematics, astronomy and life and medical sciences.

Nicole Soranzo named among Italy’s Top 38 Women Scientists in biomedicine

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Nicole Soranzo named among Italy’s Top 38 Women Scientists in biomedicine

Award recognises the impact of Sanger Institute researcher’s work in driving forward biomedical science

Wellcome Trust Sanger Institute Faculty member, Professor Nicole Soranzo has been named by the Italian National Observatory on Women’s Health, as an inaugural member of its “Top Italian Women Scientists” club.

Closing the Evidence Gap on Public Attitudes Toward Genetic Data Handling

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Closing the Evidence Gap on Public Attitudes Toward Genetic Data Handling

The Global Alliance for Genomics and Health (GA4GH) and the Wellcome Genome Campus have launched a new project to explore global public attitudes and beliefs around the sharing of genetic information.

The need to understand the public's understanding and views on this genetic data has become increasingly urgent as we enter a new era of genomic medicine in which unique ethical and moral questions arise, at both the personal and political levels. It also raises questions about the commercial use of people’s genetic information.

X-Men Inheritance - research project launched to discover how families understand genetics

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X-Men Inheritance - research project launched to discover how families understand genetics

A new study at the Wellcome Genome Campus will use popular films such as the X-Men series to explore how stories can help families engage with new developments in genetics.

Researchers are exploring how families talk about these issues, and is using people’s own interests and knowledge, such as the ‘X-men’ franchise, to help spark engagement with the emerging challenges of genomics and health.

Tracking the last Ebola cases in Sierra Leone

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Tracking the last Ebola cases in Sierra Leone

Ebola virus genomes were sequenced in a temporary laboratory at the outbreak treatment centre

Some of the final cases of Ebola in Sierra Leone were transmitted via unconventional routes, such as semen and breastmilk, according to the largest analysis to date of the tail-end of the epidemic.  Using real-time sequencing of Ebola virus genomes carried out in a temporary laboratory in the country, researchers produced a detailed picture of the latter stages of the outbreak in Sierra Leone.

Superbug infections tracked across Europe

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Superbug infections tracked across Europe

The Centre for Genomic Pathogen Surveillance has developed a new web-based tool that can track the spread of MRSA

For the first time, scientists have shown that MRSA (methicillin-resistant Staphylococcus aureus) and other antibiotic-resistant ‘superbug’ infections can be tracked across Europe by combining whole-genome sequencing with a web-based system. Researchers from the Centre for Genomic Pathogen Surveillance worked with a European network to successfully visualise and interpret the spread of drug-resistant MRSA.

Bugs as drugs

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Bugs as drugs

Harnessing novel gut bacteria for human health

Scientists at the Wellcome Trust Sanger Institute have grown and catalogued more than 130 bacteria from the human intestine. Published in Nature, this research will enable scientists to understand how our bacterial ‘microbiome’ helps keep us healthy and start to create tailor-made treatments with specific beneficial bacteria.

Five new breast cancer genes found

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Five new breast cancer genes found

Discovery of mutations paves the way for personalised treatment of breast cancer

The largest-ever study to sequence the whole genomes of breast cancers has uncovered five new genes associated with the disease and 13 new mutational signatures that influence tumour development. The results of two papers published in Nature and Nature Communications also reveal what genetic variations exist in breast cancers and where they occur in the genome. This paves the way for personalised treatment of breast cancer.

Modern DNA reveals ancient male population explosions linked to migration and technology

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Modern DNA reveals ancient male population explosions linked to migration and technology

Y chromosomes bear the marks of a series of explosive increases in male numbers linked to human development

The largest ever study of global genetic variation in the human Y chromosome has uncovered the hidden history of men. Research published today in Nature Genetics reveals explosions in male population numbers in five continents, occurring at times between 55 thousand and four thousand years ago.

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