News Archive

News Archive

Mapping A Road To Understanding Human Health

Mapping A Road To Understanding Human Health

International HapMap Project Starts the Cartography of Human Genome Variation

The quest to track down genes involved in health and disease and our response to treatments is a long and difficult challenge. Today (18th December 2003), in the journal Nature, the International HapMap Consortium, to which The Wellcome Trust is a major contributor, describes important new tools it will produce to enhance our use of the human genome sequence and to fast-track that quest.

Sanger's Celestial Spiral Staircase

Sanger's Celestial Spiral Staircase

Wellcome Trust Sanger Institute completes two billion genetic letters

The Wellcome Trust Sanger Institute has broken a genetic decoding record on its tenth anniversary which could literally take it out of this world. The landmark completion of two billion letters of sequenced DNA will push biomedicine to a new level. It could also do that figuratively: if this DNA were scaled up to the size of a spiral staircase it would reach to the moon.

Largest bite at the human genome

Largest bite at the human genome

Wellcome Trust Sanger Institute doubles gene count on chromosome 6

Is there a most valuable part of the human genome? Many corners could be argued, but a strong case can be made for part of chromosome 6, the complete sequence of which is published today by researchers from the Wellcome Trust Sanger Institute in the journal Nature. Chromosome 6, weighing in at more than 166 million chemical letters, or bases, of DNA, is the largest to be fully analysed to date.

New Wellcome Trust Campus Build 'Tops Out'

New Wellcome Trust Campus Build 'Tops Out'

Construction of the extended Wellcome Trust Genome Campus reached a major milestone today [Wednesday October 15 2003], with completion of the concrete frame of the new laboratory accommodation which will house the Wellcome Trust Sanger Institute's new programmes of research activities.

Since completing the human genome sequence - as well as a host of other genomes - the focus of the Institute has been on understanding the messages in genes in order to improve the treatment of human disease.

Epigenomics And The Wellcome Trust Sanger Institute Launch Human Epigenome Project To Follow EU-Pilot Study

Epigenomics And The Wellcome Trust Sanger Institute Launch Human Epigenome Project To Follow EU-Pilot Study

Epigenomics AG and The Wellcome Trust Sanger Institute announced today an agreement to fund and carry out the first phase of the Human Epigenome Project (HEP).

The HEP will identify and describe sites in the human genome at which cytosine bases are modified by DNA methylation (see Notes). This announcement follows the successful completion of the HEP pilot study funded by the European Union (FP5): the data from the pilot study are released today on the HEP's website.

The Finished Human Genome - Wellcome To The Genomic Age

The Finished Human Genome - Wellcome To The Genomic Age

The International Human Genome Consortium today announced the successful completion of the Human Genome Project more than two years ahead of schedule.

The Wellcome Trust Sanger Institute, which was the only British organisation involved in the project, carried out nearly one-third of the work, making it the biggest contributor.*

Undercover Infective - Cracking the Code of a Quiet Killer

Undercover Infective - Cracking the Code of a Quiet Killer

If you wanted to make sure you could hide while living amongst your enemies, what would you do? Learn to be a master of disguise and change your disguise frequently. Establish a seemingly intimate relationship with them. And not kill too many.

But now some of T. whipplei's secrets have been stripped bare by researchers working at the Wellcome Trust Sanger Institute in Cambridgeshire, and colleagues in the UK, the US and Germany and it is hoped this will help explain how other pathogens survive and proliferate.

The Measure Of Man

The Measure Of Man

Mouse genome dictionary identifies 1200 new genes in the human book of life. The sequence and analysis of more than 95 percent of the mouse genome is published for the first time in today's edition of Nature (5 December).

In addition to revealing 9000 new mouse genes, the research papers reveal 1200 new human genes, a significant number of which are likely to be involved in cancers and other diseases. These findings will allow researchers to home in more rapidly on genes in order to better diagnose and treat many human diseases.

Plans to extend leading Genome Campus get go-ahead

Plans to extend leading Genome Campus get go-ahead

Planning permission has been granted for a 27,000 sqm extension to the Wellcome Trust Genome Campus at Hinxton, home to the internationally renowned Sanger Institute.

The new development will bring industry and academic scientists together to allow data emerging from the Sanger Institute's flagship venture, the Human Genome Project, to be translated into practical health benefits.

Sir John Sulston awarded the 2002 Nobel Prize for Physiology or Medicine

Sir John Sulston awarded the 2002 Nobel Prize for Physiology or Medicine

In 1992, Sulston was appointed the first Director of the Wellcome Trust Sanger Institute in Cambridgeshire which made the UK's contribution to the international Human Genome Project.

Following publication of the first draft sequence of the human genome in 2000 he was listed among the UK's 100 most powerful people by the Observer newspaper. Sir John received his knighthood for services to genome research in the 2001 New Year's Honours. He stepped down as Director in September 2000 but continues to work on C. elegans at the Institute.

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