21 Jul 2016

Study explains genetic effect on cognition

Researchers have found a gene responsible for an intellectual disability disorder and proven how it works. Published in the American Journal of Human Genetics, the study details the role of a gene called BCL11A in a new intellectual disability syndrome.

12 Jul 2016

The burden of mutations is comparable to an extra 21 years of sun exposure

Researchers have proved that gene variants associated with red hair, pale skin and freckles are linked to a higher number of genetic mutations in skin cancers. The burden of mutations associated with these variants is comparable to an extra 21 years of sun exposure in people without this variant. 

11 Jul 2016

Human Cancer Models Initiative (HCMI) will create globally accessible bank of around 1,000 cancer cell models.

An international project to develop a large, globally accessible, bank of new cancer cell culture models for the research community has been launched. The Human Cancer Models Initiative (HCMI) will bring together expertise from around the world to make around 1,000 cancer cell models.

11 Jul 2016

Head of the Cellular Genetics Programme at the Wellcome Trust Sanger Institute is honoured for her work in computational biology and bioinformatics

Dr Sarah Teichmann, has been honoured with a Fellowship by the International Society for Computational Biology (ISCB) in recognition of her exceptional contributions to the fields of computational biology and bioinformatics. As part of the award, the head of the Cellular Generation Programme and group leader at the Wellcome Trust Sanger Institute and EMBL-European Bioinformatics Institute (EMBL-EBI) will give a keynote talk on "Understanding Cellular Heterogeneity" at the Intelligent Systems for Molecular Biology conference today (Monday 11 July) in Orlando. 

7 Jul 2016

Large-scale study could increase success rate of developing personalised cancer treatments

Research published in Cell has shown that patient-derived cancer cell lines harbour most of the same genetic changes found in patients’ tumours, and could be used to learn how tumours are likely to respond to new drugs, increasing the success rate for developing new personalised cancer treatments.

6 Jul 2016

A new atlas of gene expression during the earliest stages of life boosts studies of development

In the first genome-scale experiment of its kind, researchers have gained new insights into how a mouse embryo first begins to transform from a ball of unfocussed cells into a small, structured entity. Published on 6 July in Nature, the single-cell genomics study was led by the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust–MRC Cambridge Stem Cell Institute.

27 Jun 2016

Plasmodium vivax study shows genomic surveillance could guide health strategies

The malaria parasite Plasmodium vivax is evolving rapidly to adapt to conditions in different geographical locations, in particular to defend itself against widely-used antimalarial drugs. The study shows that genomic surveillance could be used to guide effective strategies for malaria control and elimination.

9 Jun 2016

Landmark study shows genetic changes explain differences in survival for young AML patients.

Ground-breaking study shows that Acute Myeloid Leukaemia (AML) is not a single disorder, but at least 11 different diseases, and that genetic changes explain differences in survival among young AML patients. Published in the New England Journal of Medicine, the largest study of its kind on the genetics of AML could improve clinical trials and the way patients are diagnosed and treated in the future.

9 Jun 2016

The Global Alliance for Genomics and Health (GA4GH) calls for a federated data ecosystem for sharing genomic and clinical data, in Science (9 June 2016)

The Science article authored by a diverse team of international leaders in academia, research, medicine, and industry, argues that a common framework of principles, protocols, and interoperable technical systems are necessary to enable responsible and effective data sharing.

31 May 2016

Associate Faculty member recognised for research into the genomics of autism spectrum disorder Rett Syndrome

The ‘Nobel of the East’ is awarded by the Hong Kong-based Shaw Prize Foundation, to honour recent breakthroughs by active researchers in the fields of mathematics, astronomy and life and medical sciences.