News Archive - 2004

News Archive - 2004

International HapMap Consortium Releases All Data to the Public

International HapMap Consortium Releases All Data to the Public

HapMap Will Help Identify Genetic Contributions to Disease

The International HapMap Consortium announced today (10th December 2004) at a meeting in Tokyo that all its data will be available without any restrictions, following its success in production of raw data for the Project. The Consortium has removed a defensive mechanism known as a 'click-wrap' license designed to prevent others restricting access to this valuable information.

Genomic Bookmarks Uncovered

Genomic Bookmarks Uncovered

First Chapter of Human Epigenome Project

Somewhere, we all have a textbook from school with pencilled notes in the margin which tell us which bits should be remembered and which bits we can forget. Sometimes, we change our minds and erase the notes, or add new ones. Our friends make different notes and remember different key passages.

Top Award to Sanger Scientist

Top Award to Sanger Scientist

Lord Lloyd of Kilgerran Award Lecture

Dr Richard Durbin delivered the Lord Lloyd of Kilgerran Award Lecture on 26 October 2004. The Award is made each year to "a person who has applied science and technology for the benefit of society." Previous recipients include Sir Tim Berners-Lee, the "father of the internet", James Dyson, the inventor of the cyclone vacuum cleaner, and Tim Smit, the Chief Executive of the Eden Project.

The finished human genome

The finished human genome

The "Gold Standard" sequence

The International Human Genome Sequencing Consortium, of which the Wellcome Trust Sanger Institute is a major partner, today published their scientific analysis of the finished human genome, the Gold Standard sequence that is already acting to prime new biomedical research.

A Switch for Lung Cancer

A Switch for Lung Cancer

Gene Mutation suggests Targeted Treatments

One in five people in the developed world will die of the diseases we call cancer. What they die of is not one disease, but a bewildering array of cancers, each of which behaves differently, grows differently and - crucially - responds to treatment differently.

Getting a Grip on the Great Mimicker

Getting a Grip on the Great Mimicker

Secrets of a Stealth Organism

Living amongst the roots of tropical plants is a soil bacterium with the unwieldy name Burkholderia pseudomallei - or often 'The Great Mimicker'. This organism can cause blood disease, abscesses, lung disease, kidney disease, heart disease and more. In some areas of the world, half of teenagers with blood infections die. Sometimes it lays dormant for years before striking.

MICER: a resource to help understand disease

MICER: a resource to help understand disease

Making sense of the mouse genome

With the sequencing of the mouse genome at The Wellcome Trust Sanger Institute and other centres nearing completion, an extensive and increasingly accurate catalogue of mouse genes is available. The mouse gene set will work to help us understand the function of human genes in health and disease.

Superbug's Pick'n'Mix DNA

Superbug's Pick'n'Mix DNA

UK MRSA genome decoded

Today (24 June 2004), researchers from The Wellcome Trust Sanger Institute and their colleagues announce the completion of the genome sequence of an MRSA strain and its antibiotic-sensitive 'cousin' MSSA. The strain of MRSA chosen, which causes half of all UK outbreaks, contains several unique genetic elements that are related to its virulence and drug resistance. It has emerged as a major threat in only the past ten years.

Richard Durbin, Deputy Director of the Wellcome Trust Sanger Institute, Elected to the Royal Society

Richard Durbin, Deputy Director of the Wellcome Trust Sanger Institute, Elected to the Royal Society

Dr Richard Durbin, Deputy Director of The Wellcome Trust Sanger Institute, has been elected to a Fellowship of the UK's most prestigious scientific organization, the Royal Society.

Dr Durbin is a leading expert in bioinformatics - using computers and software to understand biological process. Ten years ago, the largest available genome sequences were viruses with a few hundred thousand DNA bases. Today, we have many genomes - including human - that contain billions of bases. Sophisticated computational tools are needed to help researchers make use of all this information. A leading example is the Ensembl genome browser, developed by Durbin's team, which receives approaching 1 million hits each week.

One-tenth of our genome in one day: from sequence to disease to evolution

One-tenth of our genome in one day: from sequence to disease to evolution

Wellcome Trust Sanger Institute decodes human chromosome 9 and 10

In two landmark reports published today in Nature (27th May 2004), researchers from Wellcome Trust Sanger Institute and their collaborators announce the findings of their study of the finished sequence of human chromosomes 9 and 10. Together, these chromosomes comprise one-tenth of our human genome.

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