23 Sep 2016
Sanger Institute Faculty member is recognised for his contribution to bioinformatics
Sanger Institute Faculty member Richard Durbin was honoured for a lifetime of pioneering research and innovation in the field of bioinformatics with the prestigious International Steven Hoogendijk Award at a ceremony on 23 September 2016.
21 Sep 2016
Evidence found for a single major 'Out of Africa' migration event
16 Sep 2016
Regular updates and exchanges of cancer data in childhood cancer will help both institutions and will be made freely available to researchers worldwide
The Wellcome Trust Sanger Institute is combining the power of COSMIC, its large-scale cancer genetics database, with ProteinPaint data mining and visualization system at St. Jude Children’s Research Hospital in Memphis TN, to support the discovery and understanding of genetic mutations in paediatric cancers.
12 Sep 2016
Two characteristic patterns of DNA damage found
For the first time, researchers from the Wellcome Trust Sanger Institute and their collaborators have been able to identify in human cancers two characteristic patterns of DNA damage caused by ionising radiation. These fingerprint patterns may now enable doctors to identify which tumours have been caused by radiation, and investigate if they should be treated differently.
22 Aug 2016
Two novel African types differ genetically to Western Salmonella Enteritidis
Salmonella Enteritidis is a major cause of blood poisoning and death in Africa and food poisoning in the Western World. The first global-scale genetic study of has discovered that there are in fact three separate types. Two novel African types look the same, but are genetically different from the common Western type.
22 Aug 2016
Oesophageal cancers driven by 'marginal gain' rather than speed
New study finds that unexpectedly, oesophageal cancer cells do not divide faster than their normal neighbours. But unlike normal cells, the tumour cells produce slightly more dividing daughter cells than non-dividing ones, forming a tumour.
1 Aug 2016
The international study sequenced and analysed the protein-coding segments of the genome of 1,900 congenital heart disease patients and their parents
In one of the largest international genetic studies of congenital heart disease (CHD), researchers have discovered gene mutations linked to three new rare congenital heart disorders. Published in Nature Genetics today (1 August), the researchers also found the first clear evidence of genetic differences between two forms of the disease, and that one form can be traced back to healthy parents.
21 Jul 2016
Study explains genetic effect on cognition
Researchers have found a gene responsible for an intellectual disability disorder and proven how it works. Published in the American Journal of Human Genetics, the study details the role of a gene called BCL11A in a new intellectual disability syndrome.
12 Jul 2016
The burden of mutations is comparable to an extra 21 years of sun exposure
Researchers have proved that gene variants associated with red hair, pale skin and freckles are linked to a higher number of genetic mutations in skin cancers. The burden of mutations associated with these variants is comparable to an extra 21 years of sun exposure in people without this variant.
11 Jul 2016
Human Cancer Models Initiative (HCMI) will create globally accessible bank of around 1,000 cancer cell models.
An international project to develop a large, globally accessible, bank of new cancer cell culture models for the research community has been launched. The Human Cancer Models Initiative (HCMI) will bring together expertise from around the world to make around 1,000 cancer cell models.