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Wellcome Trust Sanger Institute,
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  • Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.

    Behjati S, Tarpey PS, Haase K, Ye H, Young MD et al.

    Nature communications 2017;8;15936

  • Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.

    Byars SG, Huang QQ, Gray LA, Bakshi A, Ripatti S et al.

    PLoS genetics 2017;13;6;e1006328

  • Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila.

    David S, Sánchez-Busó L, Harris SR, Marttinen P, Rusniok C et al.

    PLoS genetics 2017;13;6;e1006855

  • De novo yeast genome assemblies from MinION, PacBio and MiSeq platforms.

    Giordano F, Aigrain L, Quail MA, Coupland P, Bonfield JK et al.

    Scientific reports 2017;7;1;3935

  • Fine-mapping inflammatory bowel disease loci to single-variant resolution.

    Huang H, Fang M, Jostins L, Umićević Mirkov M, Boucher G et al.

    Nature 2017;547;7662;173-178

  • Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.

    Kar G, Kim JK, Kolodziejczyk AA, Natarajan KN, Torlai Triglia E et al.

    Nature communications 2017;8;1;36

  • Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.

    Kas SM, de Ruiter JR, Schipper K, Annunziato S, Schut E et al.

    Nature genetics 2017

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

    Meehan TF, Conte N, West DB, Jacobsen JO, Mason J et al.

    Nature genetics 2017

  • Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice.

    Messner CB, Driscoll PC, Piedrafita G, De Volder MFL and Ralser M

    Proceedings of the National Academy of Sciences of the United States of America 2017;114;28;7403-7407

  • In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors.

    Nelson AC, Cutty SJ, Gasiunas SN, Deplae I, Stemple DL and Wardle FC

    Cell reports 2017;19;13;2782-2795

  • The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability.

    Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J et al.

    Nature genetics 2017

  • Expanded repertoire of RASGRP2 variants responsible for platelet dysfunction and severe bleeding.

    Westbury SK, Canault M, Greene D, Bermejo E, Hanlon K et al.

    Blood 2017

  • Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.

    Xue Y, Mezzavilla M, Haber M, McCarthy S, Chen Y et al.

    Nature communications 2017;8;15927

  • SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes.

    Yeo CR, Agrawal M, Hoon S, Shabbir A, Shrivastava MK et al.

    Scientific reports 2017;7;1;4031