Phenotyping Data for Fbxo7 (MEBV) Associated with 'hematopoietic system' (MP:0005397)

Haematology (CBC): Haematology V2 (Ketamine / Xylazine) - significant parameters
Haematology (week 16) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Non-fasted mice are terminally anaesthetised with ketamine/xylazine, and blood is collected into EDTA coated tubes via the retro-orbital sinus. Whole blood is analysed for the following parameters: White and red blood cell counts, mean corpuscular volume, haemoglobin, erythrocyte indices (haematocrit, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, red blood cell distribution width), platelet counts and mean platelet volume. All blood samples are analysed with an automatic haematology analyser using volume impedance principle (scilVet Animal Blood Counter, RAB 015 A Ind.F, 01.09.03).
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Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Hom
Male
Hom
population
parameter
Graph MP Annotation
White Blood Cell Count
Red Blood Cell Count view graph MP:0002875 - decreased erythrocyte cell number
Mean Corpuscular Volume view graph MP:0002590 - increased mean corpuscular volume
Haemoglobin view graph MP:0002874 - decreased hemoglobin content
Haematocrit view graph MP:0000208 - decreased hematocrit
Mean Corpuscular Haemoglobin
Mean Corpuscular Haemoglobin Conc.
Red Blood Cell Distribution Width view graph MP:0010067 - increased red blood cell distribution width
Platelet Count view graph MP:0005505 - increased platelet cell number
Mean Platelet Volume
Peripheral Blood Leukocytes: PBL Flow Cytometry Analysis - LSR II (2 panel with activation markers) - significant parameters
Flow Cytometry (week 16) [Mice were fed on Mouse Breeder Diet (5021,Labdiet) from weaning]: analysis is performed on heparinised blood for the following parameters: Percentages of total T cells (CD3+) , CD4+ and CD8+ T cells, NKT cells (CD3+NK1.1+), NK cells (CD3-NK1.1+), B cells (CD19+), Granulocytes
view legend
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Hom
Male
Hom
population
parameter
Graph MP Annotation
T cell CD3+ percentage view graph MP:0005018 - decreased T cell number
T cell CD4+ percentage view graph MP:0008075 - decreased CD4-positive T cell number
Treg cell CD25+ percentage
T cell CD8+ percentage
CD4+CD44+CD62L- percentage view graph MP:0010835 - increased CD4-positive
CD8+CD44+CD62L- percentage view graph MP:0010838 - increased CD8-positive
B cell CD19+ percentage
Mature B cell IgD+ percentage
Granulocyte Gr1+ percentage
NKT cell percentage
NK cell percentage
Monocyte percentage