Plasma Chemistry Data for Ezr (MDYB)
Plasma Chemistry (Ketamine / Xylazine)
Comprehensive Clinical Chemistry Panel (week 16) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Non-fasted mice are terminally anaesthetised with ketamine/xylazine, and blood is collected into Lithium/Heparin coated tubes via the retro-orbital sinus. Plasma is analysed for the following parameters on an Olympus AU400:
Electrolytes: Sodium, potassium, chloride
Non-Fasted Metabolic Panel: Glucose, fructosamine, triglycerides, cholesterol, high density lipoprotein, low density lipoprotein, non-esterified free fatty acids (NEFAC) and glycerol
Pancreatic Enzyme: Amylase
Liver/Muscle Panel: Alanine aminotransferase, alkaline phosphatase, creatine kinase, aspartate aminotransferase, total bilirubin
Protein Parameters: Total protein, albumin
Kidney Panel: Creatinine, urea
Minerals and Iron: Calcium, magnesium, iron, phosphate For a subset of genes, plasma lactate dehydrogenase and uric acid are analysed.
Plasma insulin concentration is measured by Mesoscale Discovery (MSD) array technology.
Electrolytes: Sodium, potassium, chloride
Non-Fasted Metabolic Panel: Glucose, fructosamine, triglycerides, cholesterol, high density lipoprotein, low density lipoprotein, non-esterified free fatty acids (NEFAC) and glycerol
Pancreatic Enzyme: Amylase
Liver/Muscle Panel: Alanine aminotransferase, alkaline phosphatase, creatine kinase, aspartate aminotransferase, total bilirubin
Protein Parameters: Total protein, albumin
Kidney Panel: Creatinine, urea
Minerals and Iron: Calcium, magnesium, iron, phosphate For a subset of genes, plasma lactate dehydrogenase and uric acid are analysed.
Plasma insulin concentration is measured by Mesoscale Discovery (MSD) array technology.
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| Legend - hover over each heading to get a more complete description | ||||||||
| Test complete and data/resources are available | Test is complete and the data are considered interesting | Preliminary indication of an interesting phenotype | ||||||
| Test is complete but the data are not considered interesting | Test not performed or applicable | Test pending | ||||||
| Test abandoned | ||||||||
| Parameter | Female Het |
Male Het |
population parameter |
Graph | MP Annotation |
|---|---|---|---|---|---|
| Sodium | |||||
| Potassium | |||||
| Chloride | |||||
| Glucose | |||||
| Fructosamine | |||||
| Triglycerides | |||||
| Cholesterol | |||||
| High Density Lipoprotein | |||||
| Low Density Lipoprotein | |||||
| NEFAC | |||||
| Glycerol | |||||
| Insulin (MSD) | |||||
| Total Thyroxine | |||||
| Amylase | |||||
| Alanine Aminotransferase | |||||
| Alkaline Phosphatase | |||||
| Creatine Kinase | |||||
| Aspartate Aminotransferase | |||||
| Total Bilirubin | |||||
| Total Protein | |||||
| Albumin | |||||
| Creatinine | |||||
| Urea | |||||
| Calcium | |||||
| Magnesium | |||||
| Iron | |||||
| Phosphate |