Phenotyping Data for Fbxo47 (MDTZ) Associated with 'behavior/neurological' (MP:0005386)

Grip Strength: Standard Protocol
Grip Strength (week 9) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Neuromuscular function and muscle strength are assessed with a Bioseb grip strength meter. Three trials each of fore paws and all paws are performed immediately following each other.
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Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Het
Female
Hom
Male
Het
Male
Hom
population
parameter
Graph MP Annotation
Grip Strength Fore Paws Trial 1
Grip Strength Fore Paws Trial 2
Grip Strength Fore Paws Trial 3
Grip Strength All Paws Trial 1
Grip Strength All Paws Trial 2
Grip Strength All Paws Trial 3
Indirect Calorimetry: Standard Protocol
Indirect Calorimetry (week 12, male mice prioritised) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Respiratory metabolic function is assessed using the LabMaster system (TSE-systems). Mice are housed individually in calorimetry cages for a period of approximately 21 hours including a 5 hour light phase acclimatisation period. This is followed consecutively by a 12 hour dark (19:30 - 07:30) and minimum 3 hour light phase. Cumulative food intake, activity (beam breaks), volume of oxygen consumed and volume of carbon dioxide produced are all measured. From this data the respiratory exchange ratio and energy expenditure are derived. Water bottles are weighed before and after the experiment to assess water consumption.
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Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Male
Het
Male
Hom
population
parameter
Graph MP Annotation
Cumulative Food Intake
Water Intake
X-Activity Total
X-Activity Ambulatory
Eye Morphology: Eye Morphology v3
Eye Morphology (week 15) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Mice are assessed for gross morphological changes to the eye using a slit lamp (Zeiss SL130) and ophthalmoscope (Heine Omega 500). The eye is examined both undilated and dilated (tropicamide and/or neosynephrine). Images on the slit lamp are collected using a Leica DFC420. Images of the fundus are collected by using a topical endoscope (BERCI Tele-Otoscope with HOPKINS straight forward 0?, diameter 3mm, Halogen cold light fountain light source) and camera (Nikon D40x with Nikon AF 85mm F1.8D AF Nikkor lens).
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Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Het
Female
Hom
Male
Het
Male
Hom
population
parameter
Graph MP Annotation
Pupil light response