Plasma Chemistry Data for Cbx6 (MCTQ)

Plasma Chemistry (Ketamine / Xylazine)
Plasma Chemistry Panel (week 16) [Mice were fed on High Fat Diet (21.4% crude fat content, Western RD, 829100, Special Diets Services) from 4 weeks of age]: Non-fasted mice are terminally anaesthetised with ketamine/xylazine, and blood is collected into Lithium/Heparin coated tubes via the retro-orbital sinus. Plasma is analysed for the following parameters on an Olympus AU400:
Electrolytes: Sodium, potassium, chloride
view legend
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Male
Hom
population
parameter
Graph MP Annotation
Sodium
Potassium
Chloride
Glucose
Fructosamine
Triglycerides
Cholesterol
High Density Lipoprotein
Low Density Lipoprotein
NEFAC
Glycerol
Insulin (MSD)
Amylase
Alanine Aminotransferase
Alkaline Phosphatase
Creatine Kinase
Aspartate Aminotransferase
Total Bilirubin
Total Protein
Albumin
Creatinine
Urea
Calcium
Magnesium
Iron
Phosphate
Plasma Chemistry (Ketamine / Xylazine) - significant parameters
Comprehensive Clinical Chemistry Panel (week 16) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Non-fasted mice are terminally anaesthetised with ketamine/xylazine, and blood is collected into Lithium/Heparin coated tubes via the retro-orbital sinus. Plasma is analysed for the following parameters on an Olympus AU400:
Electrolytes: Sodium, potassium, chloride
Non-Fasted Metabolic Panel: Glucose, fructosamine, triglycerides, cholesterol, high density lipoprotein, low density lipoprotein, non-esterified free fatty acids (NEFAC) and glycerol
Pancreatic Enzyme: Amylase
Liver/Muscle Panel: Alanine aminotransferase, alkaline phosphatase, creatine kinase, aspartate aminotransferase, total bilirubin
Protein Parameters: Total protein, albumin
Kidney Panel: Creatinine, urea
Minerals and Iron: Calcium, magnesium, iron, phosphate For a subset of genes, plasma lactate dehydrogenase and uric acid are analysed.
Plasma insulin concentration is measured by Mesoscale Discovery (MSD) array technology.
view legend
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Hom
Male
Hom
population
parameter
Graph MP Annotation
Sodium view graph MP:0005633 - increased circulating sodium level
Potassium
Chloride view graph MP:0003019 - increased circulating chloride level
Glucose view graph MP:0005560 - decreased circulating glucose level
Fructosamine
Triglycerides view graph MP:0002644 - decreased circulating triglyceride level
Cholesterol view graph MP:0005179 - decreased circulating cholesterol level
High Density Lipoprotein view graph MP:0000186 - decreased circulating HDL cholesterol level
Low Density Lipoprotein
NEFAC
Glycerol
Insulin (MSD) view graph MP:0002727 - decreased circulating insulin level
Total Thyroxine
Amylase
Alanine Aminotransferase
Alkaline Phosphatase
Creatine Kinase
Aspartate Aminotransferase
Total Bilirubin
Total Protein
Albumin
Creatinine
Urea
Calcium
Magnesium
Iron
Phosphate