Viability at Weaning Data for Arhgef4 (MCDC)

# Mice # Wild Type # Heterozygotes # Homozygotes Wild Type Ratio Heterozygote Ratio Homozygote Ratio Homozygous Lethality
136 36 67 33 26% 49% 24% Viable
Breeding Breakdown
Breakdown of genotyped mice.
Homozygous Lethality - How Is This Calculated?

For each allele in the colony, all the genotyped mice from het x het matings are considered. If there are at least 28 mice, the proportion of homozygous mice is calculated.

  • >13% Homozygous = Viable
  • >0% and ≤13% = Subviable
  • 0% = Lethal