Phenotyping Data for Dusp3 (MBVF) Associated with 'endocrine/exocrine gland' (MP:0005379)

Dysmorphology: Dysmorphology
Dysmorphology (week 10) [Mice were fed on High Fat Diet (21.4% crude fat content, Western RD, 829100, Special Diets Services) from 4 weeks of age]: Whole body morphology is examined using a standardised checklist. The coat and whiskers are examined using a standardised checklist at a separate time point (week 4). Hair follicle cycling is assessed at approximately 43 days of age. It is considered normal that, at this age, the mouse has exited anagen phase.
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Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Hom
Male
Hom
population
parameter
Graph MP Annotation
Genitalia Morphology
Genitalia Size
Tail Epidermis Wholemount: Standard Protocol
Tail Epidermis Whole mount Collaboration (week 16) [Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning]: Whole mount preparations of tail epidermis are prepared essentially as described by Braun et al (Development 130:5241-5255, 2003). Whole mounts are labeled with antibodies to keratin 14 (red) and keratin 15 (green), and counter-stained with DAPI to reveal cell nuclei (blue). Keratin 14 is expressed by undifferentiated cells in the hair follicles, sebaceous glands and interfollicular epidermis. Keratin 15 is expressed by the reservoir of stem cells in the hair follicle bulge. This phenotyping collaboration is performed with Fiona Watt and colleagues at the Cambridge Research Institute.
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Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter population
parameter
Graph MP Annotation
Tail Epidermis Wholemount