Auditory Brainstem Response (ABR) measurement for Apoetm1UncMGP Pipeline 2
- ABR thresholds normal
- Auditory Brainstem Responses (ABRs) are recorded via subcutaneous needle electrodes placed at the vertex and behind the left ear, as an average of 256 responses to presentation of freefield stimuli [clicks (10us) or tone pips (5ms tone pips, 1ms rise/fall time)], presented at 42.2/sec.
- ABR Thresholds are determined and plotted as a function of stimulus. Mean Threshold is plotted (+/- population standard deviation). The green shaded area indicates the mean threshold (+/- 1SD and +/- 2SD) of a large population of wildtype mice of this genetic background.
- Click-Evoked ABRs waveforms were analysed. Amplitudes and Latencies for waves P1, N1, P3 and N3 were recorded and are plotted as a function of absolute sound pressure level (SPL) and SPL relative to threshold. Means are plotted (+/- population standard deviation).
ABR Thresholds Summary
ABR Thresholds and Waveforms