Phenotyping Data for Baz1b (MACW) Associated with 'cardiovascular system' (MP:0005385)

Eye Morphology: Standard Protocol
Eye Morphology (week 13) (Mice were fed on Mouse Breeder Diet (5021, Labdiet) from weaning): Mice are assessed for gross morphological changes to the eye using a slit lamp (Zeiss SL130) and ophthalmoscope (Heine Omega 500). The eye is examined both undilated and dilated (tropicamide and/or neosynephrine). Images on the slit lamp are collected using a Leica DFC420. Images of the fundus are collected by using a topical endoscope (BERCI Tele-Otoscope with HOPKINS straight forward 0?, diameter 3mm, Halogen cold light fountain light source) and camera (Nikon D40x with Nikon AF 85mm F1.8D AF Nikkor lens).
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Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Het
Male
Het
population
parameter
Graph MP Annotation
Blood Presence
Cornea Vascularization
Right Eye Blood Vessels
Left Eye Blood Vessels
Right Eye Blood Vessels Structure
Left Eye Blood Vessels Structure
Right Eye Blood Vessels Pattern
Left Eye Blood Vessels Pattern
Heart Weight: Standard Protocol
Heart Weights (week 15) [Mice were fed on High Fat Diet (21.4% crude fat content, Western RD, 829100, Special Diets Services) from 4 weeks of age]: After the terminal bleed, hearts are dissected and weighed.
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Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Het
Female
Hom
Male
Het
Male
Hom
population
parameter
Graph MP Annotation
Heart Weight
Non-Invasive Blood Pressure: Standard Protocol
Blood Pressure and Heart rate (week 11) [Mice were fed on High Fat Diet (21.4% crude fat content, Western RD, 829100, Special Diets Services) from 4 weeks of age]: Measured using a tail cuff system (MC4000, Hatteras Instruments). To minimize discomfort of the mice during the procedure they are held in a darkened restrainer which is placed on a heated platform (38 degrees celsius), and a cuff is secured at the base of the tail. The procedure is spread over 5 days, including one training and 4 measurement days, each consisting of 5 acclimatisation and 15 measurement cycles.
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Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter Female
Het
Female
Hom
Male
Het
Male
Hom
population
parameter
Graph MP Annotation
Heart Rate
Systolic Pressure
Diastolic Pressure
Recessive Lethal Study: Standard Protocol
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Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned
Parameter population
parameter
Graph MP Annotation
Recessive Lethal Study