Browsing Data by Marker Symbol: 'F'

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F10	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F10 was found for the following reasons:

synonym	-	fX
colony_prefix	-	F10 (G07)
go_ontology	-	of biological quality \| response to stress \| regulation of body fluid levels \| response to wounding
go_term	-	regulation of body fluid levels
marker_name	-	coagulation factor X
symbol	-	F10
interpro_desc	-	Epidermal growth factor-like domain
marker_symbol_str	-	F10
escell	-	HEPD0602_2_F07
go	-	regulation of body fluid levels
marker_symbol	-	F10
omim_desc	-	Factor X deficiency
interpro	-	IPR000742\|\|EG-like_dom\|\|Epidermal growth factor-like domain
GO	-	regulation of body fluid levels

Gene Details

Marker Name(s):	coagulation factor X view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AI194738, Cf10, fX
Location:	Chr8:13037308-13056676(+)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:103107	Ensembl Gene ID:	ENSMUSG00000031444	Vega Gene ID:	OTTMUSG00000020614
Entrez Gene ID:	14058	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F10	2159
Rat	F10	29243

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice

Allele Name

Allele Type

EMMA ID

Colony Prefix

ES Cell/Common Name

Genetic Background

QC/Screening Data

MI/Distribution Centre

contact distributor

F10^{tm1a(EUCOMM)Hmgu}

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

EM:06365

F10 (G07)

HEPD0602_2_G07

C57BL/6NTac;C57BL/6NTac;C57BL/6N-A^tm1Brd/a

view data
( about )

Harwell

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	na	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	na
LacZ SR-PCR	na	5' Cassette Integrity		Neo SR-PCR	na
Mutant Specific SR-PCR	na	LoxP Confirmation	na	3' LR-PCR	na
Genotyping Comment

view original data

Data provided by The International Knockout Mouse Consortium (IKMC), The European Mouse Mutant Archive (EMMA)

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 71996)	order	order	view details

ES Cell Clones

Cassette Type

5 Knockout-First Alleles

16 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0602_2_D05

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_D07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_F07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_G07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	pass	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	pass
3' LR-PCR	-

HEPD0602_2_H05

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0602_2_A05

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_A07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_B07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_B08

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_C05

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_C06

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_C07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_C08

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_D06

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_E06

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_E08

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_F06

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_F08

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_G05

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_H06

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0602_2_H07

PG00187_Z_2_H02

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
240272	PG00187_Z_2_H02	PCS00187_A_B11	L1L2_Bact_P	L3L4_pD223_DTA_spec	view
240272	PG00187_Z_2_H02	PCS00187_A_B11	L1L2_Bact_P	L3L4_pD223_DTA_spec	view

	Vectors	ES Cells
KOMP-Regeneron	Design Finished/Oligos Ordered		Projects: VG12321

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
16	16	0	2	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F10ex

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F10ex was found for the following reasons:

marker_name	-	f10 exencephaly
symbol	-	F10ex
marker_symbol_str	-	F10ex
marker_symbol	-	F10ex

Gene Details

Marker Name(s):	f10 exencephaly view this gene in MGI
Marker Type:	heritable phenotypic marker
Synonyms:
Location:	Chr8

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:3578139	Ensembl Gene ID:		Vega Gene ID:
Entrez Gene ID:		CCDS ID:

view original data

Data provided by Mouse Genome Informatics (MGI)

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

F11	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F11 was found for the following reasons:

synonym	-	FXI
go_ontology	-	of biological quality \| response to stress \| regulation of body fluid levels \| response to wounding
go_term	-	regulation of body fluid levels
marker_name	-	coagulation factor XI
symbol	-	F11
marker_symbol_str	-	F11
go	-	regulation of body fluid levels
marker_symbol	-	F11
omim_desc	-	Factor XI deficiency, autosomal recessive
GO	-	regulation of body fluid levels

Gene Details

Marker Name(s):	coagulation factor XI view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	1600027G01Rik, AI503996, Cf11, FXI, plasma thromboplastin antecedent
Location:	Chr8:45241170-45262031(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:99481	Ensembl Gene ID:	ENSMUSG00000031645	Vega Gene ID:
Entrez Gene ID:	109821	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F11	2160
Rat	F11	290757

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM	Vector Unsuccessful - Project Terminated		Projects: 71998, 78978

	Vectors	ES Cells
KOMP-Regeneron	Design Finished/Oligos Ordered		Projects: VG12332

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
25	4	0	0	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F11r	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F11r was found for the following reasons:

marker_name	-	F11 receptor
symbol	-	F11r
marker_symbol_str	-	F11r
escell	-	HEPD0709_2_F06
marker_symbol	-	F11r

Gene Details

Marker Name(s):	F11 receptor view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AA638916, BV11 antigen, ESTM33, JAM-1, JAM-A, Jcam1, Ly106
Location:	Chr1:171437535-171464603(+)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1321398	Ensembl Gene ID:	ENSMUSG00000038235	Vega Gene ID:	OTTMUSG00000021724
Entrez Gene ID:	16456	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F11R	50848
Rat	F11r	116479

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 73964)	order	order	view details

ES Cell Clones

Cassette Type

9 Knockout-First Alleles

10 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0709_2_B06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_B07

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_D05

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_D08

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_E06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_E07

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_E08

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_F06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_G05

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0709_2_A06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_A07

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_B05

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_B08

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_C06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_C08

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_D06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_D07

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_G06

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0709_2_H08

PG00119_Y_6_C07

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
107638	PG00119_Y_6_C07	PCS00119_A_G10	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view
107638	PG00119_Y_6_C07	PCS00119_A_G10	L1L2_Bact_P	R3R4_pBR_DTA+_Bsd_amp	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
36	9	0	2	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F12	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F12 was found for the following reasons:

synonym	-	FXII
colony_prefix	-	F12
go_ontology	-	of acute inflammatory response \| positive regulation of protein processing \| Factor XII activation
go_term	-	Factor XII activation
marker_name	-	coagulation factor XII (Hageman factor)
symbol	-	F12
interpro_desc	-	FN_type2_col-bd
marker_symbol_str	-	F12
escell	-	EPD0207_1_F08
go	-	Factor XII activation
marker_symbol	-	F12
omim_desc	-	Factor XII deficiency
interpro	-	IPR000562\|\|FN_type2_col-bd\|\|Fibronectin, type II, collagen-binding
GO	-	Factor XII activation

Gene Details

Marker Name(s):	coagulation factor XII (Hageman factor) view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	FXII
Location:	Chr13:55417958-55426793(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1891012	Ensembl Gene ID:	ENSMUSG00000021492	Vega Gene ID:	OTTMUSG00000035495
Entrez Gene ID:	58992	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F12	2161
Rat	F12	306761

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-CSD (Project: 34408)	order	order	view details

ES Cell Clones

Cassette Type

7 Knockout-First Alleles

9 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0882_2_C04

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	pass

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0882_2_D04

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0882_2_E01

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0882_2_E04

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	pass

Distribution Centre
Karyotype	-	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	fail	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0882_2_G02

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	pass

Distribution Centre
Karyotype	-	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	fail	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_H07

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	pass

Distribution Centre
Karyotype	0.9 - 0.81	Copy Number	pass	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_H07

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1a(KOMP)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	pass

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	pass	LACZ	pass
Chromosome 1	pass	Chromosome 8a	pass	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	pass	Chromosome Y	pass

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

DEPD00582_6_A05

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(KOMP)Mbp

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	-	3' Screen	no reads detected
Loss of WT Allele (LOA)	pass	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0882_2_B04

PG00097_Z_1_G12

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm2e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not attempted	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_B07

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_B08

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_C07

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_D08

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_E08

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_F08

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0207_1_G08

PRPGS00097_A_G12

C57BL/6N

JM8.N4

tm1e(KOMP)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
96515	PG00097_Z_1_G12	PCS00097_A_G12	L1L2_Bact_P	L4L3_pD223_DTA_spec	view
96515	PG00097_Z_1_G12	PCS00097_A_G12	L1L2_Bact_P	L4L3_pD223_DTA_spec	view
96515	PRPGS00097_A_G12	PCS00097_A_G12	L1L2_Bact_P	L4L3_pD223_DTA_spec	view
96515	PRPGS00097_A_G12	PCS00097_A_G12	L1L2_Bact_P	L4L3_pD223_DTA_spec	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
22	9	0	4	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F13a1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F13a1 was found for the following reasons:

synonym	-	Factor XIIIA
go_ontology	-	of biological quality \| response to stress \| regulation of body fluid levels \| response to wounding
go_term	-	regulation of body fluid levels
marker_name	-	coagulation factor XIII, A1 subunit
symbol	-	F13a1
marker_symbol_str	-	F13a1
go	-	regulation of body fluid levels
marker_symbol	-	F13a1
omim_desc	-	Factor XIIIA deficiency
GO	-	regulation of body fluid levels

Gene Details

Marker Name(s):	coagulation factor XIII, A1 subunit view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	1200014I03Rik, AI462306, Factor XIIIA
Location:	Chr13:36867178-37050244(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:1921395	Ensembl Gene ID:	ENSMUSG00000039109	Vega Gene ID:
Entrez Gene ID:	74145	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F13A1	2162
Rat	F13a1	60327

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
KOMP-Regeneron (Project: VG11602)	order	order	view details

ES Cell Clones

Cassette Type

2 Deletion Alleles

Promotor Driven

Allele:	genbank file
Targeting Vector:	genbank file

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

11602B-B6

VG11602

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

11602B-H8

VG11602

C57BL/6NTac

VGB6

tm1(KOMP)Vlcg

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
	VG11602		ZEN-Ub1		view

	Vectors	ES Cells
EUCOMM	Vector Unsuccessful - Project Terminated		Projects: 72051

	Vectors	ES Cells
NorCOMM	Vector - Initial Attempt Unsuccessful		Projects: 66143

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
58	6	5	0	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F13b	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F13b was found for the following reasons:

go_ontology	-	of biological quality \| response to stress \| regulation of body fluid levels \| response to wounding
go_term	-	regulation of body fluid levels
marker_name	-	coagulation factor XIII, beta subunit
symbol	-	F13b
marker_symbol_str	-	F13b
go	-	regulation of body fluid levels
marker_symbol	-	F13b
omim_desc	-	Factor XIIIB deficiency
GO	-	regulation of body fluid levels

Gene Details

Marker Name(s):	coagulation factor XIII, beta subunit view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	Cf-13b, Cf13b
Location:	Chr1:139501707-139523756(+)

Related Human Conditions (from OMIM)

Factor XIIIB deficiency

More Information

MGI Gene Accession:	MGI:88379	Ensembl Gene ID:	ENSMUSG00000026368	Vega Gene ID:	OTTMUSG00000021467
Entrez Gene ID:	14060	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F13B	2165

view original data

Data provided by Mouse Genome Informatics (MGI), OMIM, Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
NorCOMM (Project: 71287)	order	order	view details

ES Cell Clones

Cassette Type

1 Deletion Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

N02057P1_C_231W_C8

N02057P1_T_189.3_G03

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
243233	N02057P1_T_189.3_G03	N02057P1_I_189.3_G03	L1L2_GOHANU	L3L4_pZero_DTA_kan	view

	Vectors	ES Cells
EUCOMM	Redesign Requested		Projects: 92254, 102871, 74145, 77411, 37417, 116725

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
22	5	0	0	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F2	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F2 was found for the following reasons:

synonym	-	FII
colony_prefix	-	F2 (E10)
go_ontology	-	of biological quality \| response to stress \| regulation of body fluid levels \| response to wounding \| cellular
go_term	-	regulation of body fluid levels
marker_name	-	coagulation factor II
symbol	-	F2
interpro_desc	-	Kringle-like fold
targeting_vector	-	PG00225_Z_4_F11
marker_symbol_str	-	F2
escell	-	HEPD0720_4_F11
go	-	regulation of body fluid levels
marker_symbol	-	F2
interpro	-	IPR013806\|\|Kringle-like\|\|Kringle-like fold
GO	-	regulation of body fluid levels

Gene Details

Marker Name(s):	coagulation factor II view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	Cf-2, Cf2, FII, prothrombin, thrombin
Location:	Chr2:91625329-91636407(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:88380	Ensembl Gene ID:	ENSMUSG00000027249	Vega Gene ID:	OTTMUSG00000014282
Entrez Gene ID:	14061	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F2	2147
Rat	F2	29251

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
NorCOMM (Project: 42781)	order	order	view details

ES Cell Clones

Cassette Type

8 Deletion Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

N01571P1_C_64W_B5

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_C3

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_C4

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_E3

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_E4

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_F2

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_F3

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

N01571P1_C_64W_H3

N01571P1_T_160.6_A07

C57BL/6N

Deletion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	-	LoxP Screen	-	3' Screen	-
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
116439	N01571P1_T_160.6_A07	N01571P1_I_160.6_A07	L1L2_GOHANU	L3L4_pZero_DTA_kan	view

	Vectors	ES Cells
EUCOMM (Project: 37044)	order	order	view details

ES Cell Clones

Cassette Type

19 Knockout-First Alleles

9 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0720_4_A11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_B09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_B10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_B11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_C09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_C10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_C11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_C12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_D09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_D12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_E10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	pass	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	pass
3' LR-PCR	-

HEPD0720_4_E11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_E12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_F10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_F11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_F12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_G09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_G11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_H09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Hmgu

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

HEPD0720_4_A09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_A12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_B12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_D10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_E09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_F09

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_G10

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_G12

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

HEPD0720_4_H11

PG00225_Z_4_B06

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Hmgu

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
286728	PG00225_Z_4_B06	PCS00225_A_D03	L1L2_Bact_P	L3L4_pD223_DTA_T_spec	view
286728	PG00225_Z_4_B06	PCS00225_A_D03	L1L2_Bact_P	L3L4_pD223_DTA_T_spec	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
23	6	1	2	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F2r	Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F2r was found for the following reasons:

go_ontology	-	metabolic process \| regulation of primary metabolic process \| regulation of molecular function \| regulation
go_term	-	regulation of molecular function
marker_name	-	coagulation factor II (thrombin) receptor
symbol	-	F2r
marker_symbol_str	-	F2r
go	-	regulation of molecular function
marker_symbol	-	F2r
GO	-	regulation of molecular function

Gene Details

Marker Name(s):	coagulation factor II (thrombin) receptor view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	AI482343, Cf2r, Par1, ThrR, thrombin receptor
Location:	Chr13:95601789-95618433(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:101802	Ensembl Gene ID:	ENSMUSG00000048376	Vega Gene ID:
Entrez Gene ID:	14062	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F2R	2149
Rat	F2r	25439

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 49445)	order	order	view details

ES Cell Clones

Cassette Type

1 Knockout-First Alleles

0 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Targeting Vector:

genbank file | image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0236_1_G10

PRPGS00092_C_B11

C57BL/6N

JM8.N4

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
87372	PRPGS00092_C_B11	PCS00092_C_B11	L1L2_Bact_P	L3L4_pD223_DTA_spec	view

	Vectors	ES Cells
KOMP-Regeneron	Design Not Possible		Projects: VG15073

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
30	5	0	1	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

F2rl1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources

F2rl1 was found for the following reasons:

go_ontology	-	necrosis factor-mediated signaling pathway \| negative regulation of tumor necrosis factor-mediated
go_term	-	negative regulation of tumor necrosis factor-mediated signaling pathway
marker_name	-	coagulation factor II (thrombin) receptor-like 1
symbol	-	F2rl1
targeting_vector	-	PG00202_Z_5_F01
marker_symbol_str	-	F2rl1
escell	-	EPD0592_3_F01
go	-	positive regulation of glomerular filtration
marker_symbol	-	F2rl1
ikmc_project_id	-	IST14602F6
GO	-	positive regulation of glomerular filtration

Gene Details

Marker Name(s):	coagulation factor II (thrombin) receptor-like 1 view this gene in MGI
Marker Type:	protein coding gene
Synonyms:	Gpcr11, PAR-2, Par2, Protease-activated receptor-2, proteinase-activated receptor-2
Location:	Chr13:95511732-95525240(-)

Related Human Conditions (from OMIM) - no related Human Condition

More Information

MGI Gene Accession:	MGI:101910	Ensembl Gene ID:	ENSMUSG00000021678	Vega Gene ID:
Entrez Gene ID:	14063	CCDS ID:

Interpro Families

Orthologs / Homologs

Species	Marker Symbol	Entrez Gene ID	Ensembl Gene ID
Human	F2RL1	2150
Rat	F2rl1	116677

view original data

Data provided by Mouse Genome Informatics (MGI), Ensembl

WTSI Phenotyping no data available

Mice

Allele Name

Allele Type

EMMA ID

Colony Prefix

ES Cell/Common Name

Genetic Background

QC/Screening Data

MI/Distribution Centre

currently unavailable

F2rl1^{tm1a(EUCOMM)Wtsi}

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

EM:06771

P4161-EPD0592_3_B02

EPD0592_3_B02

C57BL/6NTac;C57BL/6NTac;C57BL/6N-A^tm1Brd/a

view data
( about )

ICS/

Southern Blot	na	TV Backbone Assay	na	5' LR-PCR	na
Loss of WT Allele (LOA) qPCR	na	Homozygous Loss of WT Allele (LOA) SR-PCR	na	Neo Count (qPCR)	na
LacZ SR-PCR	pass	5' Cassette Integrity		Neo SR-PCR	pass
Mutant Specific SR-PCR	pass	LoxP Confirmation	pass	3' LR-PCR	na
Genotyping Comment

view original data

Data provided by The International Knockout Mouse Consortium (IKMC), The European Mouse Mutant Archive (EMMA)

IKMC Vectors and ES Cells

	Vectors	ES Cells
EUCOMM (Project: 78671)	order	order	view details

ES Cell Clones

Cassette Type

13 Knockout-First Alleles

11 Targeted Non-Conditional Alleles

Promotor Driven

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

Allele:	genbank file \| image
Targeting Vector:	genbank file \| image

view all available ES cell clones

ES Cell Clones With Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0592_3_A02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_A03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	not confirmed	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_B02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	pass	Map Test	-	Karyotype	pass
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	pass
3' LR-PCR	-

EPD0592_3_B04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_C02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_C04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_D02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	pass	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	pass	Map Test	-	Karyotype	pass
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	pass
3' LR-PCR	-

EPD0592_3_E04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	pass	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_F01

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_G02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_G04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_H01

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	pass	5' SR-PCR	pass	3' SR-PCR	pass
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_H03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1a(EUCOMM)Wtsi

Knockout-First - Reporter Tagged Insertion (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	pass	3' Screen	pass
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

ES Cell Clones Without Conditional Potential

ES Cell Clone

Targeting Vector

ES Cell Strain

ES Cell Line

Allele

Allele Type

QC/Screening Data

EPD0592_3_A04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_B03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_D03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_D04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_E02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_E03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_F03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_G01

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_G03

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_H02

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

EPD0592_3_H04

PG00202_Z_5_A04

C57BL/6N-A^tm1Brd/a

JM8A3.N1

tm1e(EUCOMM)Wtsi

Targeted Non-Conditional (Promotor Driven Cassette)

view data ( about )

Production Centre
5' Screen	pass	LoxP Screen	not confirmed	3' Screen	not confirmed
Loss of WT Allele (LOA)	-	Vector Integrity	-

Distribution Centre
Karyotype	-	Copy Number	-	Cells Thawed Correctly	-
5' LR-PCR	-	5' SR-PCR	-	3' SR-PCR	-
LOA	-	LOXP	-	LACZ	-
Chromosome 1	-	Chromosome 8a	-	Chromosome 8b	-
Chromosome 11a	-	Chromosome 11b	-	Chromosome Y	-

User/Mouse Clinic
Southern Blot	-	Map Test	-	Karyotype	-
TV Backbone Assay	-	5' LR-PCR	-	Loss of WT Allele (LOA)	-
Neo Count (qPCR)	-	LacZ SR-PCR	-	5' Cassette Integrity	-
Neo SR-PCR	-	Mutant Specific SR-PCR	-	LoxP Confirmation	-
3' LR-PCR	-

Targeting Vectors

Design	Targeting Vector	Intermediate Vector	Cassette	Backbone	Targeting Vector Genbank File
87373	PG00202_Z_5_A04	PCS00202_A_E12	L1L2_Bact_P	L3L4_pD223_DTA_T_spec	view
87373	PG00202_Z_5_A04	PCS00202_A_E12	L1L2_Bact_P	L3L4_pD223_DTA_T_spec	view

view original data

Data provided by The International Knockout Mouse Consortium (IKMC)

DNA Clone Resources

C57Bl/6J Bacs	129 Bacs	MICER clones	KO Targeting Vectors
30	4	1	2	view in Ensembl

view original data

Data provided by The Wellcome Trust Sanger Institute (WTSI)

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