Mouse Resources Portal

About This Portal

The Wellcome Trust Sanger Institute generates, characterises, and uses a variety of reagents for mouse genetics research. It also aims to facilitate the distribution of these resources to the external scientific community. Here, you will find unified access to the different resources available from the Institute or its collaborators. The resources include: 129S7 and C57BL6/J bacterial artificial chromosomes (BACs), MICER gene targeting vectors, knock-out first conditional-ready gene targeting vectors, embryonic stem (ES) cells with gene targeted mutations or with retroviral gene trap insertions, mutant mouse lines, and phenotypic data generated from the Institute's primary screen.

Phenotyping Summary The table below displays the number of alleles that have completed different stages of the MGP Phenotyping pipeline (funded by WTSI & EUMODIC) Comprehensive Phenotyping Substantively Complete 395 Infection Challenge (Salmonella and Citrobacter) 308 LacZ Expression (Adult and E14.5) 333 Other Data Summary The table below displays the number of unique genes with each individual product type produced at the Wellcome Trust Sanger Institute. Funding: WTSI EUMODIC KOMP EUCOMM KOMP EUCOMM WT WT WT Products: Mice Targeted ES Cells Gene Targeting Vectors MICER C57Bl/6J BACs 129S7 BACs 578 12094 14314 6862 12318 12148

Phenotyping Overview Download a heat map of phenotyping results by assay. This spreadsheet also links to the detailed phenotyping data on this portal. You can also access (and search) the same data via the MGP Phenotyping BioMart. If you would like to be kept updated with information on our phenotyping data, please subscribe to our mailing list.

Viewing Our Data in Ensembl

Most of the products found within this portal can also be viewed as DAS tracks in the Ensembl genome browser. Follow these links to have the tracks automatically activated for you:

• IKMC alleles in Ensembl Mouse
• Sanger DNA products in Ensembl Mouse
• IKMC alleles on orthologous genes in Ensembl Human

Get in Touch For enquiries about the data displayed in this portal (or requests for further information), please contact MGPEnquiries@sanger.ac.uk. For enquiries about access to mouse lines, please contact mouseinterest@sanger.ac.uk. If you have any problems/comments with regards to this portal, or would like to request a new feature please send an email to mouseportal@sanger.ac.uk, we'd like to hear from you!