Cancer Genome Project
Cancer Genetics & Genomics
Archive Page
This page is maintained as a historical record and is no longer being updated.
The Cancer Genome Project research group finished their work at the Sanger Institute in 2024. This page is no longer being updated but is being maintained as a historical record of the research of the group during its time at the Sanger Institute.
Cancer is caused by the genetic changes acquired by our cells as we go through life. We used cutting-edge DNA sequencing methods to identify these genetic changes, known as mutations, from human cancer samples. Our aim was to discover the genes that are frequently mutated in tumours, since these provide important insights into the biology of cancer. We also studied the patterns of mutations we see in cancer cells. These patterns represent a record of the cancer’s life history, and can illustrate the damaging factors the genome has been exposed to as the cancer has evolved from a normal cell.
Our people
Group lead
Core team
 
      
      Elizabeth Anderson
Scientific Manager
 
      
      Dr Kathryn Beal
Senior Software Developer
 
      
      Mr Shriram G Bhosle
Principal Software Developer
 
      
      Calli Latimer
Project Coordinator: Stratton Faculty - Cancer, Ageing and Somatic Mutation Programme
 
      
      Emily Mitchell
PhD Student
 
      
      Laura O'Neill
Scientific Manager
 
      
      Rebecca Shepherd
Senior Software Developer
Previous core team members
 
      
      Dr Nicos Angelopoulos
Senior Staff Scientist
 
      
      Graham Bignell
Senior Staff Scientist
 
      
      Dr Aikaterini Chatzipli
Postdoctoral Fellow
 
      
      Dr Simon Forbes
Head of COSMIC
 
      
      Dr Anthony Fullam
Postdoctoral Fellow
 
      
      Stephen J Gamble
Research Assistant
 
      
      Dominik Glodzik
Postdoctoral Fellow
 
      
      Angela Macharia
Project Manager
 
      
      Dr Ultan McDermott
Honorary Faculty and Former Group Leader
 
      
      Mr Stuart McLaren
Project Manager
 
      
      Dr Tibor Nagy
Senior Bioinformatician
 
      
      Stanley Ng
Postdoctoral Fellow
 
      
      Dr Serena Nik-Zainal
CRUK Advanced Clinician Scientist and Former Wellcome Sanger Institute Group Leader
 
      
      Nikita Patel
Research Assistant
 
      
      Mia Petljak
Former Postdoctoral Fellow at the Sanger Institute
 
      
      Nicola D Roberts
Former PhD Student at the Sanger Institute
 
      
      Lucy A Stebbings
Principal Bioinformatician
Related groups
Partners
We work with the following groups
 
          