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Catalogue Of Somatic Mutations In Cancer

What is COSMIC?

All cancers arise as a result of the acquisition of a series of fixed DNA sequence abnormalities, mutations, many of which ultimately confer a growth advantage upon the cells in which they have occurred. There is a vast amount of information available in the published scientific literature about these changes. COSMIC is designed to store and display somatic mutation information and related details and contains information relating to human cancers. [more]

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  • Enter a Gene, Sample, Tissue or Mutation Description


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Additional Information
Data in COSMIC is curated from known Cancer Genes Literature and Systematic Screens.
Interested in receiving COSMIC news and release information? Then sign up [here].

Please send all comments and suggestions to the COSMIC team at cosmic@sanger.ac.uk

COSMIC data is freely downloadable in many formats on our FTP site:
ftp://ftp.sanger.ac.uk/pub/CGP/cosmic

Additional information on COSMIC content.
News
23rd May 2012

COSMIC v59 Release

COSMIC v59 Release

This latest release of COSMIC includes full mutation spectra across three new cancer genes and 9 new gene fusions. Also ...

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Component Projects

  • Cancer Cell Line Project

  • Genomics of Drug Sensitivity 

  • CGP Trace and Genotype Archive

  • COSMIC Biomart

  • CGP Resequencing Studies

  • Cancer Gene Census

Statistics

Experiments 4799855
Tumours 713382
Mutations 282779
References 13728
Genes 21425
Fusions 7732
Structural Variants 2883
Whole Cancer Genomes 1436
 

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Last Modified Fri Apr 27 10:27:42 2012

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