[2009] [2008] [2007] [2006] [2005] [2004] [2003] [2002] [2001] [2000] [1999] [1998] [1997] [1996] [1995] [1994] [1993] [1992] [1991] [1990] [1989] [1988] 

• 2009 [Page Top]
• • LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.
    Mahoney CL, Choudhury B, Davies H, Edkins S, Greenman C, Haaften G, Mironenko T, Santarius T, Stevens C, Stratton MR, Futreal PA
    Br J Cancer. 2009;100;370-5. PMID: 19165201 DOI: 10.1038/sj.bjc.6604886
    

 

• 2008 [Page Top]
• • The emerging landscape of breast cancer susceptibility.
    Stratton MR, Rahman N
    Nat Genet. 2008;40;17-22. PMID: 18163131 DOI: 10.1038/ng.2007.53
    
  • Genome resequencing and genetic variation.
    Stratton M
    Nat Biotechnol. 2008;26;65-6. PMID: 18183021 DOI: 10.1038/nbt0108-65
    
  • Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors.
    Linger R, Dudakia D, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Stoppa-Lyonnet D, Bonaïti-Pellié C, Heidenreich A, Albers P, Olah E, Geczi L, Bodrogi I, Daly PA, Guilford P, Fosså SD, Heimdal K, Tjulandin SA, Liubchenko L, Stoll H, Weber W, Einhorn L, McMaster M, Korde L, Greene MH, Nathanson KL, Cortessis V, Easton DF, Bishop DT, Stratton MR, Rapley EA
    Genes Chromosomes Cancer. 2008;47;247-52. PMID: 18069663 DOI: 10.1002/gcc.20526
    
  • The Catalogue of Somatic Mutations in Cancer (COSMIC).
    Forbes SA, Bhamra G, Bamford S, Dawson E, Kok C, Clements J, Menzies A, Teague JW, Futreal PA, Stratton MR
    Curr Protoc Hum Genet. 2008;Chapter 10;Unit 10.11. PMID: 18428421 DOI: 10.1002/0471142905.hg1011s57
    
  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.
    Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H, Santarius T, Stebbings LA, Leroy C, Edkins S, Hardy C, Teague JW, Menzies A, Goodhead I, Turner DJ, Clee CM, Quail MA, Cox A, Brown C, Durbin R, Hurles ME, Edwards PA, Bignell GR, Stratton MR, Futreal PA
    Nat Genet. 2008;. PMID: 18438408 DOI: 10.1038/ng.128
    
  • Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature.
    Coffey J, Linger R, Pugh J, Dudakia D, Sokal M, Easton DF, Timothy Bishop D, Stratton M, Huddart R, Rapley EA
    Genes Chromosomes Cancer. 2008;47;34-42. PMID: 17943970 DOI: 10.1002/gcc.20503
    
  • SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome.
    Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE, Undlien DE, Strømme P
    Am J Hum Genet. 2008;82;1003-10. PMID: 18342287 DOI: 10.1016/j.ajhg.2008.01.013
    
  • Refined mapping of X-linked reticulate pigmentary disorder and sequencing of candidate genes.
    Jaeckle Santos LJ, Xing C, Barnes RB, Ades LC, Megarbane A, Vidal C, Xuereb A, Tarpey PS, Smith R, Khazab M, Shoubridge C, Partington M, Futreal A, Stratton MR, Gecz J, Zinn AR
    Hum Genet. 2008;. PMID: 18404279 DOI: 10.1007/s00439-008-0498-4
    
  • X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.
    Dibbens LM, Tarpey PS, Hynes K, Bayly MA, Scheffer IE, Smith R, Bomar J, Sutton E, Vandeleur L, Shoubridge C, Edkins S, Turner SJ, Stevens C, O'Meara S, Tofts C, Barthorpe S, Buck G, Cole J, Halliday K, Jones D, Lee R, Madison M, Mironenko T, Varian J, West S, Widaa S, Wray P, Teague J, Dicks E, Butler A, Menzies A, Jenkinson A, Shepherd R, Gusella JF, Afawi Z, Mazarib A, Neufeld MY, Kivity S, Lev D, Lerman-Sagie T, Korczyn AD, Derry CP, Sutherland GR, Friend K, Shaw M, Corbett M, Kim HG, Geschwind DH, Thomas P, Haan E, Ryan S, McKee S, Berkovic SF, Futreal PA, Stratton MR, Mulley JC, Gécz J
    Nat Genet. 2008;40;776-81. PMID: 18469813 DOI: 10.1038/ng.149
    
  • Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation.
    Molinari F, Foulquier F, Tarpey PS, Morelle W, Boissel S, Teague J, Edkins S, Futreal PA, Stratton MR, Turner G, Matthijs G, Gecz J, Munnich A, Colleaux L
    Am J Hum Genet. 2008;82;1150-7. PMID: 18455129 DOI: 10.1016/j.ajhg.2008.03.021
    
  • Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation.
    Froyen G, Corbett M, Vandewalle J, Jarvela I, Lawrence O, Meldrum C, Bauters M, Govaerts K, Vandeleur L, Van Esch H, Chelly J, Sanlaville D, van Bokhoven H, Ropers HH, Laumonnier F, Ranieri E, Schwartz CE, Abidi F, Tarpey PS, Futreal PA, Whibley A, Raymond FL, Stratton MR, Fryns JP, Scott R, Peippo M, Sipponen M, Partington M, Mowat D, Field M, Hackett A, Marynen P, Turner G, Gécz J
    Am J Hum Genet. 2008;82;432-43. PMID: 18252223 DOI: 10.1016/j.ajhg.2007.11.002
    
  • Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development.
    Wiedemeyer R, Brennan C, Heffernan TP, Xiao Y, Mahoney J, Protopopov A, Zheng H, Bignell G, Furnari F, Cavenee WK, Hahn WC, Ichimura K, Collins VP, Chu GC, Stratton MR, Ligon KL, Futreal PA, Chin L
    Cancer Cell. 2008;13;355-64. PMID: 18394558 DOI: 10.1016/j.ccr.2008.02.010
    
  • In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
    Ikediobi ON, Reimers M, Durinck S, Blower PE, Futreal AP, Stratton MR, Weinstein JN
    Mol Cancer Ther. 2008;7;1337-46. PMID: 18524847 DOI: 10.1158/1535-7163.MCT-07-2308
    
  • Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing.
    Campbell PJ, Pleasance ED, Stephens PJ, Dicks E, Rance R, Goodhead I, Follows GA, Green AR, Futreal PA, Stratton MR
    Proc Natl Acad Sci U S A. 2008;105;13081-6. PMID: 18723673 DOI: 10.1073/pnas.0801523105
    
  • Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.
    Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA, Hahn WC, Klimstra DS, Chin L, DePinho RA
    Proc Natl Acad Sci U S A. 2008;105;19372-7. PMID: 19050074 DOI: 10.1073/pnas.0809966105
    

 

• 2007 [Page Top]
• • Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans.
    Wu Y, Arai AC, Rumbaugh G, Srivastava AK, Turner G, Hayashi T, Suzuki E, Jiang Y, Zhang L, Rodriguez J, Boyle J, Tarpey P, Raymond FL, Nevelsteen J, Froyen G, Stratton M, Futreal A, Gecz J, Stevenson R, Schwartz CE, Valle D, Huganir RL, Wang T
    Proc Natl Acad Sci U S A. 2007;104;18163-8. PMID: 17989220 DOI: 10.1073/pnas.0708699104
    
  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
    Wellcome Trust Case Control Consortium , Australo-Anglo-American Spondylitis Consortium (TASC) , Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, Evans DM, Leung HT, Marchini JL, Morris AP, Spencer CC, Tobin MD, Attwood AP, Boorman JP, Cant B, Everson U, Hussey JM, Jolley JD, Knight AS, Koch K, Meech E, Nutland S, Prowse CV, Stevens HE, Taylor NC, Walters GR, Walker NM, Watkins NA, Winzer T, Jones RW, McArdle WL, Ring SM, Strachan DP, Pembrey M, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskivina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN, Ball SG, Balmforth AJ, Barrett JH, Bishop TD, Iles MM, Maqbool A, Yuldasheva N, Hall AS, Braund PS, Dixon RJ, Mangino M, Stevens S, Thompson JR, Bredin F, Tremelling M, Parkes M, Drummond H, Lees CW, Nimmo ER, Satsangi J, Fisher SA, Forbes A, Lewis CM, Onnie CM, Prescott NJ, Sanderson J, Matthew CG, Barbour J, Mohiuddin MK, Todhunter CE, Mansfield JC, Ahmad T, Cummings FR, Jewell DP, Webster J, Brown MJ, Lathrop MG, Connell J, Dominiczak A, Marcano CA, Burke B, Dobson R, Gungadoo J, Lee KL, Munroe PB, Newhouse SJ, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A, Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee , Bruce IN, Donovan H, Eyre S, Gilbert PD, Hilder SL, Hinks AM, John SL, Potter C, Silman AJ, Symmons DP, Thomson W, Worthington J, Dunger DB, Widmer B, Frayling TM, Freathy RM, Lango H, Perry JR, Shields BM, Weedon MN, Hattersley AT, Hitman GA, Walker M, Elliott KS, Groves CJ, Lindgren CM, Rayner NW, Timpson NJ, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Hill AV, Bradbury LA, Farrar C, Pointon JJ, Wordsworth P, Brown MA, Franklyn JA, Heward JM, Simmonds MJ, Gough SC, Seal S, Breast Cancer Susceptibility Collaboration (UK) , Stratton MR, Rahman N, Ban M, Goris A, Sawcer SJ, Compston A, Conway D, Jallow M, Newport M, Sirugo G, Rockett KA, Bumpstead SJ, Chaney A, Downes K, Ghori MJ, Gwilliam R, Hunt SE, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Cardin NJ, Davison D, Ferreira T, Pereira-Gale J, Hallgrimsdo'ttir IB, Howie BN, Su Z, Teo YY, Vukcevic D, Bentley D, Brown MA, Compston A, Farrall M, Hall AS, Hattersley AT, Hill AV, Parkes M, Pembrey M, Stratton MR, Mitchell SL, Newby PR, Brand OJ, Carr-Smith J, Pearce SH, McGinnis R, Keniry A, Deloukas P, Reveille JD, Zhou X, Sims AM, Dowling A, Taylor J, Doan T, Davis JC, Savage L, Ward MM, Learch TL, Weisman MH, Brown M
    Nat Genet. 2007;39;1329-37. PMID: 17952073 DOI: 10.1038/ng.2007.17
    
  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
    Wellcome Trust Case Control Consortium
    Nature. 2007;447;661-78. PMID: 17554300 DOI: 10.1038/nature05911
    
  • Rheumatoid arthritis association at 6q23.
    Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D, Hider S, Bruce IN, Wellcome Trust Case Control Consortium , Wilson AG, Marinou I, Morgan A, Emery P, YEAR Consortium , Carter A, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Strachan D, Worthington J
    Nat Genet. 2007;39;1431-3. PMID: 17982455 DOI: 10.1038/ng.2007.32
    
  • Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.
    Tarpey PS, Raymond FL, O'Meara S, Edkins S, Teague J, Butler A, Dicks E, Stevens C, Tofts C, Avis T, Barthorpe S, Buck G, Cole J, Gray K, Halliday K, Harrison R, Hills K, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Varian J, West S, Widaa S, Mallya U, Moon J, Luo Y, Holder S, Smithson SF, Hurst JA, Clayton-Smith J, Kerr B, Boyle J, Shaw M, Vandeleur L, Rodriguez J, Slaugh R, Easton DF, Wooster R, Bobrow M, Srivastava AK, Stevenson RE, Schwartz CE, Turner G, Gecz J, Futreal PA, Stratton MR, Partington M
    Am J Hum Genet. 2007;80;345-52. PMID: 17236139 DOI: 10.1086/511134
    
  • Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.
    Tarpey PS, Raymond FL, Nguyen LS, Rodriguez J, Hackett A, Vandeleur L, Smith R, Shoubridge C, Edkins S, Stevens C, O'Meara S, Tofts C, Barthorpe S, Buck G, Cole J, Halliday K, Hills K, Jones D, Mironenko T, Perry J, Varian J, West S, Widaa S, Teague J, Dicks E, Butler A, Menzies A, Richardson D, Jenkinson A, Shepherd R, Raine K, Moon J, Luo Y, Parnau J, Bhat SS, Gardner A, Corbett M, Brooks D, Thomas P, Parkinson-Lawrence E, Porteous ME, Warner JP, Sanderson T, Pearson P, Simensen RJ, Skinner C, Hoganson G, Superneau D, Wooster R, Bobrow M, Turner G, Stevenson RE, Schwartz CE, Futreal PA, Srivastava AK, Stratton MR, Gécz J
    Nat Genet. 2007;39;1127-33. PMID: 17704778 DOI: 10.1038/ng2100
    
  • A novel Gln358Glu mutation in ectodysplasin A associated with X-linked dominant incisor hypodontia.
    Tarpey P, Pemberton TJ, Stockton DW, Das P, Ninis V, Edkins S, Andrew Futreal P, Wooster R, Kamath S, Nayak R, Stratton MR, Patel PI
    Am J Med Genet A. 2007;143;390-4. PMID: 17256800 DOI: 10.1002/ajmg.a.31567
    
  • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.
    Scott LM, Tong W, Levine RL, Scott MA, Beer PA, Stratton MR, Futreal PA, Erber WN, McMullin MF, Harrison CN, Warren AJ, Gilliland DG, Lodish HF, Green AR
    N Engl J Med. 2007;356;459-68. PMID: 17267906 DOI: 10.1056/NEJMoa065202
    
  • The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene.
    Schwartz CE, Tarpey PS, Lubs HA, Verloes A, May MM, Risheg H, Friez MJ, Futreal PA, Edkins S, Teague J, Briault S, Skinner C, Bauer-Carlin A, Simensen RJ, Joseph SM, Jones JR, Gecz J, Stratton MR, Raymond FL, Stevenson RE
    J Med Genet. 2007;44;472-7. PMID: 17369503 DOI: 10.1136/jmg.2006.048637
    
  • Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.
    Raymond FL, Tarpey PS, Edkins S, Tofts C, O'Meara S, Teague J, Butler A, Stevens C, Barthorpe S, Buck G, Cole J, Dicks E, Gray K, Halliday K, Hills K, Hinton J, Jones D, Menzies A, Perry J, Raine K, Shepherd R, Small A, Varian J, Widaa S, Mallya U, Moon J, Luo Y, Shaw M, Boyle J, Kerr B, Turner G, Quarrell O, Cole T, Easton DF, Wooster R, Bobrow M, Schwartz CE, Gecz J, Stratton MR, Futreal PA
    Am J Hum Genet. 2007;80;982-7. PMID: 17436253 DOI: 10.1086/513609
    
  • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.
    Rahman N, Seal S, Thompson D, Kelly P, Renwick A, Elliott A, Reid S, Spanova K, Barfoot R, Chagtai T, Jayatilake H, McGuffog L, Hanks S, Evans DG, Eccles D, Easton DF, Stratton MR
    Nat Genet. 2007;39;165-7. PMID: 17200668 DOI: 10.1038/ng1959
    
  • Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.
    Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, Depinho RA
    Nature. 2007;. PMID: 17515920 DOI: 10.1038/nature05886
    
  • A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour.
    Linger R, Dudakia D, Huddart R, Easton D, Bishop DT, Stratton MR, Rapley EA
    Br J Cancer. 2007;96;357-61. PMID: 17211466 DOI: 10.1038/sj.bjc.6603557
    
  • Patterns of somatic mutation in human cancer genomes.
    Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, Defazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR
    Nature. 2007;446;153-8. PMID: 17344846 DOI: 10.1038/nature05610
    
  • Backseat drivers take the wheel.
    Futreal PA
    Cancer Cell. 2007;12;493-4. PMID: 18068625 DOI: 10.1016/j.ccr.2007.11.020
    
  • Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly.
    Field M, Tarpey PS, Smith R, Edkins S, O'Meara S, Stevens C, Tofts C, Teague J, Butler A, Dicks E, Barthorpe S, Buck G, Cole J, Gray K, Halliday K, Hills K, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Varian J, West S, Widaa S, Mallya U, Wooster R, Moon J, Luo Y, Hughes H, Shaw M, Friend KL, Corbett M, Turner G, Partington M, Mulley J, Bobrow M, Schwartz C, Stevenson R, Gecz J, Stratton MR, Futreal PA, Raymond FL
    Am J Hum Genet. 2007;81;367-74. PMID: 17668385 DOI: 10.1086/520677
    
  • Genome-wide association study identifies novel breast cancer susceptibility loci.
    Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham N, Ahmed S, Healey CS, Bowman R, The SEARCH collaborators , Luccarini C, Conroy D, Shah M, Munday H, Jordan C, Perkins B, West J, Redman K, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, Garcia-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B, Nevanlinna H, Fagerholm R, Eerola H, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Cox DG, Hall P, Wedren S, Liu J, Low YL, Bogdanova N, Schürmann P, Dörk T, Tollenaar RA, Jacobi CE, Devilee P, Klijn JG, Sigurdson AJ, Doody MM, Alexander BH, Zhang J, Cox A, Brock IW, Macpherson G, Reed MW, Couch FJ, Goode EL, Olson JE, Meijers-Heijboer H, van den Ouweland A, Uitterlinden A, Rivadeneira F, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Hopper JL, McCredie M, Southey M, Giles GG, Schroen C, Justenhoven C, Brauch H, Hamann U, Ko YD, Spurdle AB, Beesley J, Chen X, kConFab , Aghmesheh M, Amor D, Andrews L, Antill Y, Armes J, Armitage S, Arnold L, Balleine R, Begley G, Beilby J, Bennett I, Bennett B, Berry G, Blackburn A, Brennan M, Brown M, Buckley M, Burke J, Butow P, Byron K, Callen D, Campbell I, Chenevix-Trench G, Clarke C, Colley A, Cotton D, Cui J, Culling B, Cummings M, Dawson SJ, Dixon J, Dobrovic A, Dudding T, Edkins T, Eisenbruch M, Farshid G, Fawcett S, Field M, Firgaira F, Fleming J, Forbes J, Friedlander M, Gaff C, Gardner M, Gattas M, George P, Giles G, Gill G, Goldblatt J, Greening S, Grist S, Haan E, Harris M, Hart S, Hayward N, Hopper J, Humphrey E, Jenkins M, Jones A, Kefford R, Kirk J, Kollias J, Kovalenko S, Lakhani S, Leary J, Lim J, Lindeman G, Lipton L, Lobb L, Maclurcan M, Mann G, Marsh D, McCredie M, McKay M, Anne McLachlan S, Meiser B, Milne R, Mitchell G, Newman B, O'loughlin I, Osborne R, Peters L, Phillips K, Price M, Reeve J, Reeve T, Richards R, Rinehart G, Robinson B, Rudzki B, Salisbury E, Sambrook J, Saunders C, Scott C, Scott E, Scott R, Seshadri R, Shelling A, Southey M, Spurdle A, Suthers G, Taylor D, Tennant C, Thorne H, Townshend S, Tucker K, Tyler J, Venter D, Visvader J, Walpole I, Ward R, Waring P, Warner B, Warren G, Watson E, Williams R, Wilson J, Winship I, Young MA, AOCS Management Group , Bowtell D, Green A, Defazio A, Chenevix-Trench G, Gertig D, Webb P, Mannermaa A, Kosma VM, Kataja V, Hartikainen J, Day NE, Cox DR, Ponder BA
    Nature. 2007;. PMID: 17529967 DOI: 10.1038/nature05887
    
  • AutoCSA, an Algorithm for High Throughput DNA Sequence Variant Detection in Cancer Genomes.
    Dicks E, Teague J, Stephens P, Raine K, Yates A, Mattocks C, Tarpey P, Butler A, Menzies A, Richardson D, Jenkinson A, Davies H, Edkins S, Forbes S, Gray K, Greenman C, Shepherd R, Stratton M, Futreal P, Wooster R
    Bioinformatics. 2007;. PMID: 17485433 DOI: 10.1093/bioinformatics/btm152
    
  • The continuing search for cancer-causing somatic mutations.
    Dalgliesh GL, Futreal PA
    Breast Cancer Res. 2007;9;101. PMID: 17319975 DOI: 10.1186/bcr1654
    
  • Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, Batchelor TT, Futreal PA, Stratton MR, Curry WT, Iafrate AJ, Louis DN
    Clin Cancer Res. 2007;13;2038-45. PMID: 17404084 DOI: 10.1158/1078-0432.CCR-06-2149
    
  • Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution.
    Bignell GR, Santarius T, Pole JC, Butler AP, Perry J, Pleasance E, Greenman C, Menzies A, Taylor S, Edkins S, Campbell P, Quail M, Plumb B, Matthews L, McLay K, Edwards PA, Rogers J, Wooster R, Futreal PA, Stratton MR
    Genome Res. 2007;17;1296-303. PMID: 17675364 DOI: 10.1101/gr.6522707
    

 

• 2006 [Page Top]
• • Decoding the fine-scale structure of a breast cancer genome and transcriptome.
    Volik S, Raphael BJ, Huang G, Stratton MR, Bignel G, Murnane J, Brebner JH, Bajsarowicz K, Paris PL, Tao Q, Kowbel D, Lapuk A, Shagin DA, Shagina IA, Gray JW, Cheng JF, de Jong PJ, Pevzner P, Collins C
    Genome Res. 2006;16;394-404. PMID: 16461635
    
  • A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers.
    Thompson D, Seal S, Schutte M, McGuffog L, Barfoot R, Renwick A, Eeles R, Sodha N, Houlston R, Shanley S, Klijn J, Wasielewski M, Chang-Claude J, Futreal PA, Weber BL, Nathanson KL, Stratton M, Meijers-Heijboer H, Rahman N, Easton DF
    Cancer Epidemiol Biomarkers Prev. 2006;15;2542-5. PMID: 17164383 DOI: 10.1158/1055-9965.EPI-06-0687
    
  • Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.
    Tarpey PS, Stevens C, Teague J, Edkins S, O'Meara S, Avis T, Barthorpe S, Buck G, Butler A, Cole J, Dicks E, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, West S, Widaa S, Yates A, Catford R, Butler J, Mallya U, Moon J, Luo Y, Dorkins H, Thompson D, Easton DF, Wooster R, Bobrow M, Carpenter N, Simensen RJ, Schwartz CE, Stevenson RE, Turner G, Partington M, Gecz J, Stratton MR, Futreal PA, Raymond FL
    Am J Hum Genet. 2006;79;1119-24. PMID: 17186471 DOI: 10.1086/510137
    
  • Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.
    Tarpey P, Thomas S, Sarvananthan N, Mallya U, Lisgo S, Talbot CJ, Roberts EO, Awan M, Surendran M, McLean RJ, Reinecke RD, Langmann A, Lindner S, Koch M, Jain S, Woodruff G, Gale RP, Degg C, Droutsas K, Asproudis I, Zubcov AA, Pieh C, Veal CD, Machado RD, Backhouse OC, Baumber L, Constantinescu CS, Brodsky MC, Hunter DG, Hertle RW, Read RJ, Edkins S, O'meara S, Parker A, Stevens C, Teague J, Wooster R, Futreal PA, Trembath RC, Stratton MR, Raymond FL, Gottlob I
    Nat Genet. 2006;38;1242-4. PMID: 17013395
    
  • Her2-targeted therapies in non-small cell lung cancer.
    Swanton C, Futreal A, Eisen T
    Clin Cancer Res. 2006;12;4377s-4383s. PMID: 16857814
    
  • A genome wide linkage search for breast cancer susceptibility genes.
    Smith P, McGuffog L, Easton DF, Mann GJ, Pupo GM, Newman B, Chenevix-Trench G, kConFab Investigators , Szabo C, Southey M, Renard H, Odefrey F, Lynch H, Stoppa-Lyonnet D, Couch F, Hopper JL, Giles GG, McCredie MR, Buys S, Andrulis I, Senie R, BCFS, BRCAX Collaborators Group , Goldgar DE, Oldenburg R, Kroeze-Jansema K, Kraan J, Meijers-Heijboer H, Klijn JG, van Asperen C, van Leeuwen I, Vasen HF, Cornelisse CJ, Devilee P, Baskcomb L, Seal S, Barfoot R, Mangion J, Hall A, Edkins S, Rapley E, Wooster R, Chang-Claude J, Eccles D, Evans DG, Futreal PA, Nathanson KL, Weber BL, Breast Cancer Susceptibility Collaboration (UK) , Rahman N, Stratton MR
    Genes Chromosomes Cancer. 2006;45;646-55. PMID: 16575876
    
  • Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.
    Seal S, Thompson D, Renwick A, Elliott A, Kelly P, Barfoot R, Chagtai T, Jayatilake H, Ahmed M, Spanova K, North B, McGuffog L, Evans DG, Eccles D, Breast Cancer Susceptibility Collaboration (UK) , Easton DF, Stratton MR, Rahman N
    Nat Genet. 2006;38;1239-41. PMID: 17033622 DOI: 10.1038/ng1902
    
  • ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.
    Renwick A, Thompson D, Seal S, Kelly P, Chagtai T, Ahmed M, North B, Jayatilake H, Barfoot R, Spanova K, McGuffog L, Evans DG, Eccles D, Easton DF, Stratton MR, Rahman N
    Nat Genet. 2006;38;873-5. PMID: 16832357
    
  • Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
    Ikediobi ON, Davies H, Bignell G, Edkins S, Stevens C, O'Meara S, Santarius T, Avis T, Barthorpe S, Brackenbury L, Buck G, Butler A, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Hunter C, Jenkinson A, Jones D, Kosmidou V, Lugg R, Menzies A, Mironenko T, Parker A, Perry J, Raine K, Richardson D, Shepherd R, Small A, Smith R, Solomon H, Stephens P, Teague J, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Reinhold W, Weinstein JN, Stratton MR, Futreal PA, Wooster R
    Mol Cancer Ther. 2006;5;2606-12. PMID: 17088437 DOI: 10.1158/1535-7163.MCT-06-0433
    
  • A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
    Hunter C, Smith R, Cahill DP, Stephens P, Stevens C, Teague J, Greenman C, Edkins S, Bignell G, Davies H, O'Meara S, Parker A, Avis T, Barthorpe S, Brackenbury L, Buck G, Butler A, Clements J, Cole J, Dicks E, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Richardson D, Shepherd R, Small A, Solomon H, Tofts C, Varian J, West S, Widaa S, Yates A, Easton DF, Riggins G, Roy JE, Levine KK, Mueller W, Batchelor TT, Louis DN, Stratton MR, Futreal PA, Wooster R
    Cancer Res. 2006;66;3987-91. PMID: 16618716
    
  • Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer.
    Greenman C, Wooster R, Futreal PA, Stratton M, Easton D
    Genetics. 2006;. PMID: 16783027
    
  • Cosmic 2005.
    Forbes S, Clements J, Dawson E, Bamford S, Webb T, Dogan A, Flanagan A, Teague J, Wooster R, Futreal PA, Stratton MR
    Br J Cancer. 2006;94;318-22. PMID: 16421597
    
  • Mutations in the RSK2(RPS6KA3) gene cause Coffin-Lowry syndrome and nonsyndromic X-linked mental retardation.
    Field M, Tarpey P, Boyle J, Edkins S, Goodship J, Luo Y, Moon J, Teague J, Stratton MR, Futreal PA, Wooster R, Raymond FL, Turner G
    Clin Genet. 2006;70;509-15. PMID: 17100996 DOI: 10.1111/j.1399-0004.2006.00723.x
    
  • Recurrent KRAS Codon 146 Mutations in Human Colorectal Cancer.
    Edkins S, O'meara S, Parker A, Stevens C, Reis M, Jones S, Greenman C, Davies H, Dalgliesh G, Forbes S, Hunter C, Smith R, Stephens P, Goldstraw P, Nicholson A, Chan TL, Velculescu VE, Yuen ST, Leung SY, Stratton MR, Futreal A
    Cancer Biol Ther. 2006;5;. PMID: 16969076
    
  • High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison.
    Davies H, Dicks E, Stephens P, Cox C, Teague J, Greenman C, Bignell G, O'meara S, Edkins S, Parker A, Stevens C, Menzies A, Blow M, Bottomley B, Dronsfield M, Futreal PA, Stratton MR, Wooster R
    Genomics. 2006;. PMID: 16406726
    
  • RNA editing of human microRNAs.
    Blow MJ, Grocock RJ, van Dongen S, Enright AJ, Dicks E, Futreal PA, Wooster R, Stratton MR
    Genome Biol. 2006;7;R27. PMID: 16594986
    
  • Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
    Bignell G, Smith R, Hunter C, Stephens P, Davies H, Greenman C, Teague J, Butler A, Edkins S, Stevens C, O'Meara S, Parker A, Avis T, Barthorpe S, Brackenbury L, Buck G, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Gillis AJ, Stoop HJ, van Gurp RJ, Oosterhuis JW, Looijenga LH, Futreal PA, Wooster R, Stratton MR
    Genes Chromosomes Cancer. 2006;45;42-6. PMID: 16175573
    

 

• 2005 [Page Top]
• • The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders.
    Scott LM, Campbell PJ, Baxter EJ, Todd T, Stephens P, Edkins S, Wooster R, Stratton MR, Futreal PA, Green AR
    Blood. 2005;106;2920-1. PMID: 16204151
    
  • Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
    Bignell G, Smith R, Hunter C, Stephens P, Davies H, Greenman C, Teague J, Butler A, Edkins S, Stevens C, O'Meara S, Parker A, Avis T, Barthorpe S, Brackenbury L, Buck G, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Gillis AJ, Stoop HJ, van Gurp RJ, Oosterhuis JW, Looijenga LH, Futreal PA, Wooster R, Stratton MR
    Genes Chromosomes Cancer. 2006;45;42-6. PMID: 16175573
    
  • Somatic Mutations of the Protein Kinase Gene Family in Human Lung Cancer.
    Davies H, Hunter C, Smith R, Stephens P, Greenman C, Bignell G, Teague J, Butler A, Edkins S, Stevens C, Parker A, O'meara S, Avis T, Barthorpe S, Brackenbury L, Buck G, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Green A, Knowles M, Leung SY, Looijenga LH, Malkowicz B, Pierotti MA, Teh BT, Yuen ST, Lakhani SR, Easton DF, Weber BL, Goldstraw P, Nicholson AG, Wooster R, Stratton MR, Futreal PA
    Cancer Res. 2005;65;7591-7595. PMID: 16140923
    
  • Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype.
    Lakhani SR, Reis-Filho JS, Fulford L, Penault-Llorca F, van der Vijver M, Parry S, Bishop T, Benitez J, Rivas C, Bignon YJ, Chang-Claude J, Hamann U, Cornelisse CJ, Devilee P, Beckmann MW, Nestle-Krämling C, Daly PA, Haites N, Varley J, Lalloo F, Evans G, Maugard C, Meijers-Heijboer H, Klijn JG, Olah E, Gusterson BA, Pilotti S, Radice P, Scherneck S, Sobol H, Jacquemier J, Wagner T, Peto J, Stratton MR, McGuffog L, Easton DF, Breast Cancer Linkage Consortium
    Clin Cancer Res. 2005;11;5175-80. PMID: 16033833
    
  • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.
    Stephens P, Edkins S, Davies H, Greenman C, Cox C, Hunter C, Bignell G, Teague J, Smith R, Stevens C, O'meara S, Parker A, Tarpey P, Avis T, Barthorpe A, Brackenbury L, Buck G, Butler A, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Green A, Knowles M, Leung SY, Looijenga LH, Malkowicz B, Pierotti MA, Teh B, Yuen ST, Nicholson AG, Lakhani S, Easton DF, Weber BL, Stratton MR, Futreal PA, Wooster R
    Nat Genet. 2005;. PMID: 15908952
    
  • A survey of homozygous deletions in human cancer genomes.
    Cox C, Bignell G, Greenman C, Stabenau A, Warren W, Stephens P, Davies H, Watt S, Teague J, Edkins S, Birney E, Easton DF, Wooster R, Futreal PA, Stratton MR
    Proc Natl Acad Sci U S A. 2005;. PMID: 15761058
    
  • Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour.
    Reid S, Renwick A, Seal S, Baskcomb L, Barfoot R, Jayatilake H, Pritchard-Jones K, Stratton MR, Ridolfi-Lüthy A, Rahman N, Breast Cancer Susceptibility Collaboration (UK) , Familial Wilms Tumour Collaboration
    J Med Genet. 2005;42;147-51. PMID: 15689453
    

 

• 2004 [Page Top]
• • Lung cancer: intragenic ERBB2 kinase mutations in tumours.
    Stephens P, Hunter C, Bignell G, Edkins S, Davies H, Teague J, Stevens C, O'Meara S, Smith R, Parker A, Barthorpe A, Blow M, Brackenbury L, Butler A, Clarke O, Cole J, Dicks E, Dike A, Drozd A, Edwards K, Forbes S, Foster R, Gray K, Greenman C, Halliday K, Hills K, Kosmidou V, Lugg R, Menzies A, Perry J, Petty R, Raine K, Ratford L, Shepherd R, Small A, Stephens Y, Tofts C, Varian J, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Knowles M, Leung SY, Louis DN, Looijenga LH, Malkowicz B, Pierotti MA, Teh B, Chenevix-Trench G, Weber BL, Yuen ST, Harris G, Goldstraw P, Nicholson AG, Futreal PA, Wooster R, Stratton MR
    Nature. 2004;431;525-6. PMID: 15457249
    
  • Cancer: understanding the target.
    Stratton MR, Futreal PA
    Nature. 2004;430;30. PMID: 15229590
    
  • A census of human cancer genes.
    Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Rahman N, Stratton MR
    Nat Rev Cancer. 2004;4;177-83. PMID: 14993899
    
  • The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website.
    Bamford S, Dawson E, Forbes S, Clements J, Pettett R, Dogan A, Flanagan A, Teague J, Futreal PA, Stratton MR, Wooster R
    Br J Cancer. 2004;91;355-8. PMID: 15188009
    
  • Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation.
    Tarpey P, Parnau J, Blow M, Woffendin H, Bignell G, Cox C, Cox J, Davies H, Edkins S, Holden S, Korny A, Mallya U, Moon J, O'Meara S, Parker A, Stephens P, Stevens C, Teague J, Donnelly A, Mangelsdorf M, Mulley J, Partington M, Turner G, Stevenson R, Schwartz C, Young I, Easton D, Bobrow M, Futreal PA, Stratton MR, Gecz J, Wooster R, Raymond FL
    Am J Hum Genet. 2004;75;318-24. PMID: 15185169
    
  • Somatic mutations of KIT in familial testicular germ cell tumours.
    Rapley EA, Hockley S, Warren W, Johnson L, Huddart R, Crockford G, Forman D, Leahy MG, Oliver DT, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Heidenreich A, Geczi L, Bodrogi I, Olah E, Ormiston WJ, Daly PA, Looijenga LH, Guilford P, Aass N, Fosså SD, Heimdal K, Tjulandin SA, Liubchenko L, Stoll H, Weber W, Einhorn L, Weber BL, McMaster M, Greene MH, Bishop DT, Easton D, Stratton MR
    Br J Cancer. 2004;90;2397-401. PMID: 15150569
    
  • Gene expression profiling after radiation-induced DNA damage is strongly predictive of BRCA1 mutation carrier status.
    Kote-Jarai Z, Williams RD, Cattini N, Copeland M, Giddings I, Wooster R, tePoele RH, Workman P, Gusterson B, Peacock J, Gui G, Campbell C, Eeles R
    Clin Cancer Res. 2004;10;958-63. PMID: 14871973
    
  • High-resolution analysis of DNA copy number using oligonucleotide microarrays.
    Bignell GR, Huang J, Greshock J, Watt S, Butler A, West S, Grigorova M, Jones KW, Wei W, Stratton MR, Futreal PA, Weber B, Shapero MH, Wooster R
    Genome Res. 2004;14;287-95. PMID: 14762065
    
  • BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study.
    Casula M, Colombino M, Satta MP, Cossu A, Ascierto PA, Bianchi-Scarrà G, Castiglia D, Budroni M, Rozzo C, Manca A, Lissia A, Carboni A, Petretto E, Satriano SM, Botti G, Mantelli M, Ghiorzo P, Stratton MR, Tanda F, Palmieri G, Italian Melanoma Intergroup Study
    J Clin Oncol. 2004;22;286-92. PMID: 14722037
    
  • Amplification and overexpression of E2F3 in human bladder cancer.
    Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, Fletcher A, Edwards S, Flohr P, Falconer A, Roe T, Kovacs G, Dennis N, Fisher C, Wooster R, Huddart R, Foster CS, Cooper CS
    Oncogene. 2004;23;1627-30. PMID: 14716298
    
  • 1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis.
    Greshock J, Naylor TL, Margolin A, Diskin S, Cleaver SH, Futreal PA, deJong PJ, Zhao S, Liebman M, Weber BL
    Genome Res. 2004;14;179-87. PMID: 14672980
    
  • Mutations of BRAF and KRAS in gastric cancer and their association with microsatellite instability.
    Zhao W, Chan TL, Chu KM, Chan AS, Stratton MR, Yuen ST, Leung SY
    Int J Cancer. 2004;108;167-9. PMID: 14618633
    

 

• 2003 [Page Top]
• • Novel consensus DNA-binding sequence for BRCA1 protein complexes.
    Cable PL, Wilson CA, Calzone FJ, Rauscher FJ, Scully R, Livingston DM, Li L, Blackwell CB, Futreal PA, Afshari CA
    Mol Carcinog. 2003;38;85-96. PMID: 14502648
    
  • Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays.
    Clark J, Edwards S, Feber A, Flohr P, John M, Giddings I, Crossland S, Stratton MR, Wooster R, Campbell C, Cooper CS
    Oncogene. 2003;22;1247-52. PMID: 12606952
    
  • Amplification and overexpression of E2F3 in human bladder cancer.
    Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, Fletcher A, Edwards S, Flohr P, Falconer A, Roe T, Kovacs G, Dennis N, Fisher C, Wooster R, Huddart R, Foster CS, Cooper CS
    Oncogene. 2004;23;1627-30. PMID: 14716298
    
  • Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis.
    Hanks S, Adams S, Douglas J, Arbour L, Atherton DJ, Balci S, Bode H, Campbell ME, Feingold M, Keser G, Kleijer W, Mancini G, McGrath JA, Muntoni F, Nanda A, Teare MD, Warman M, Pope FM, Superti-Furga A, Futreal PA, Rahman N
    Am J Hum Genet. 2003;73;791-800. PMID: 14508707
    
  • Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile.
    Jenner RG, Maillard K, Cattini N, Weiss RA, Boshoff C, Wooster R, Kellam P
    Proc Natl Acad Sci U S A. 2003;100;10399-404. PMID: 12925741
    
  • Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling.
    Lee YF, John M, Edwards S, Clark J, Flohr P, Maillard K, Edema M, Baker L, Mangham DC, Grimer R, Wooster R, Thomas JM, Fisher C, Judson I, Cooper CS
    Br J Cancer. 2003;88;510-5. PMID: 12592363
    
  • Ehlers-Danlos syndrome with severe early-onset periodontal disease (EDS-VIII) is a distinct, heterogeneous disorder with one predisposition gene at chromosome 12p13.
    Rahman N, Dunstan M, Teare MD, Hanks S, Douglas J, Coleman K, Bottomly WE, Campbell ME, Berglund B, Nordenskjöld M, Forssell B, Burrows N, Lunt P, Young I, Williams N, Bignell GR, Futreal PA, Pope FM
    Am J Hum Genet. 2003;73;198-204. PMID: 12776252
    
  • Localisation of susceptibility genes for familial testicular germ cell tumour.
    Rapley EA, Crockford GP, Easton DF, Stratton MR, Bishop DT, International Testicular Cancer Linkage Consortium
    APMIS. 2003;111;128-33; discussion 33-5. PMID: 12752252
    
  • Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
    Schutte M, Seal S, Barfoot R, Meijers-Heijboer H, Wasielewski M, Evans DG, Eccles D, Meijers C, Lohman F, Klijn J, van den Ouweland A, Futreal PA, Nathanson KL, Weber BL, Easton DF, Stratton MR, Rahman N, Breast Cancer Linkage Consortium
    Am J Hum Genet. 2003;72;1023-8. PMID: 12610780
    
  • Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.
    Seal S, Barfoot R, Jayatilake H, Smith P, Renwick A, Bascombe L, McGuffog L, Evans DG, Eccles D, Easton DF, Stratton MR, Rahman N, Breast Cancer Susceptibility Collaboration
    Cancer Res. 2003;63;8596-9. PMID: 14695169
    
  • Sequence-based cancer genomics: progress, lessons and opportunities.
    Strausberg RL, Simpson AJ, Wooster R
    Nat Rev Genet. 2003;4;409-18. PMID: 12776211
    

 

• 2002 [Page Top]
• • Breast and ovarian cancer.
    Wooster R, Weber BL
    N Engl J Med. 2003;348;2339-47. PMID: 12788999
    
  • A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes.
    Antoniou AC, Pharoah PD, McMullan G, Day NE, Stratton MR, Peto J, Ponder BJ, Easton DF
    Br J Cancer. 2002;86;76-83. PMID: 11857015
    
  • BRAF and RAS mutations in human lung cancer and melanoma.
    Brose MS, Volpe P, Feldman M, Kumar M, Rishi I, Gerrero R, Einhorn E, Herlyn M, Minna J, Nicholson A, Roth JA, Albelda SM, Davies H, Cox C, Brignell G, Stephens P, Futreal PA, Wooster R, Stratton MR, Weber BL
    Cancer Res. 2002;62;6997-7000. PMID: 12460918
    
  • Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones.
    Clark J, Edwards S, John M, Flohr P, Gordon T, Maillard K, Giddings I, Brown C, Bagherzadeh A, Campbell C, Shipley J, Wooster R, Cooper CS
    Genes Chromosomes Cancer. 2002;34;104-14. PMID: 11921288
    
  • Mutations of the BRAF gene in human cancer.
    Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA
    Nature. 2002;417;949-54. PMID: 12068308
    
  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations.
    Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N, Stratton MR, CHEK2-Breast Cancer Consortium
    Nat Genet. 2002;31;55-9. PMID: 11967536
    
  • HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.
    Meitz JC, Edwards SM, Easton DF, Murkin A, Ardern-Jones A, Jackson RA, Williams S, Dearnaley DP, Stratton MR, Houlston RS, Eeles RA, Cancer Research UK/BPG UK Familial Prostate Cancer Study Collaborators
    Br J Cancer. 2002;87;905-8. PMID: 12373607
    
  • BRCA1 and BRCA2 germline mutations in Sardinian breast cancer families and their implications for genetic counseling.
    Palmieri G, Palomba G, Cossu A, Pisano M, Dedola MF, Sarobba MG, Farris A, Olmeo N, Contu A, Pasca A, Satta MP, Persico I, Carboni AA, Cossu-Rocca P, Contini M, Mangion J, Stratton MR, Tanda F
    Ann Oncol. 2002;13;1899-907. PMID: 12453858
    
  • The gene for juvenile hyaline fibromatosis maps to chromosome 4q21.
    Rahman N, Dunstan M, Teare MD, Hanks S, Edkins SJ, Hughes J, Bignell GR, Mancini G, Kleijer W, Campbell M, Keser G, Black C, Williams N, Arbour L, Warman M, Superti-Furga A, Futreal PA, Pope FM
    Am J Hum Genet. 2002;71;975-80. PMID: 12214284
    
  • BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic.
    Shih HA, Couch FJ, Nathanson KL, Blackwood MA, Rebbeck TR, Armstrong KA, Calzone K, Stopfer J, Seal S, Stratton MR, Weber BL
    J Clin Oncol. 2002;20;994-9. PMID: 11844822
    
  • Pre-counseling education materials for BRCA testing: does tailoring make a difference?
    Skinner CS, Schildkraut JM, Berry D, Calingaert B, Marcom PK, Sugarman J, Winer EP, Iglehart JD, Futreal PA, Rimer BK
    Genet Test. 2002;6;93-105. PMID: 12215248
    
  • Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium.
    Thompson D, Szabo CI, Mangion J, Oldenburg RA, Odefrey F, Seal S, Barfoot R, Kroeze-Jansema K, Teare D, Rahman N, Renard H, Mann G, Hopper JL, Buys SS, Andrulis IL, Senie R, Daly MB, West D, Ostrander EA, Offit K, Peretz T, Osorio A, Benitez J, Nathanson KL, Sinilnikova OM, Olàh E, Bignon YJ, Ruiz P, Badzioch MD, Vasen HF, Futreal AP, Phelan CM, Narod SA, Lynch HT, Ponder BA, Eeles RA, Meijers-Heijboer H, Stoppa-Lyonnet D, Couch FJ, Eccles DM, Evans DG, Chang-Claude J, Lenoir G, Weber BL, Devilee P, Easton DF, Goldgar DE, Stratton MR, KConFab Consortium
    Proc Natl Acad Sci U S A. 2002;99;827-31. PMID: 11792833
    
  • Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3.
    Udayakumar TS, Stratton MS, Nagle RB, Bowden GT
    Neoplasia. 2002;4;60-7. PMID: 11922392
    
  • Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
    Yuen ST, Davies H, Chan TL, Ho JW, Bignell GR, Cox C, Stephens P, Edkins S, Tsui WW, Chan AS, Futreal PA, Stratton MR, Wooster R, Leung SY
    Cancer Res. 2002;62;6451-5. PMID: 12438234
    

 

• 2001 [Page Top]
• • Allele loss on chromosome 1p36 in epithelial ovarian cancers.
    Alvarez AA, Lambers AR, Lancaster JM, Maxwell GL, Ali S, Gumbs C, Berchuck A, Futreal PA
    Gynecol Oncol. 2001;82;94-8. PMID: 11426968
    
  • K-ras mutations in Müllerian inclusion cysts associated with serous borderline tumors of the ovary.
    Alvarez AA, Moore WF, Robboy SJ, Bentley RC, Gumbs C, Futreal PA, Berchuck A
    Gynecol Oncol. 2001;80;201-6. PMID: 11161860
    
  • The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X.
    Bentley DR, Deloukas P, Dunham A, French L, Gregory SG, Humphray SJ, Mungall AJ, Ross MT, Carter NP, Dunham I, Scott CE, Ashcroft KJ, Atkinson AL, Aubin K, Beare DM, Bethel G, Brady N, Brook JC, Burford DC, Burrill WD, Burrows C, Butler AP, Carder C, Catanese JJ, Clee CM, Clegg SM, Cobley V, Coffey AJ, Cole CG, Collins JE, Conquer JS, Cooper RA, Culley KM, Dawson E, Dearden FL, Durbin RM, de Jong PJ, Dhami PD, Earthrowl ME, Edwards CA, Evans RS, Gillson CJ, Ghori J, Green L, Gwilliam R, Halls KS, Hammond S, Harper GL, Heathcott RW, Holden JL, Holloway E, Hopkins BL, Howard PJ, Howell GR, Huckle EJ, Hughes J, Hunt PJ, Hunt SE, Izmajlowicz M, Jones CA, Joseph SS, Laird G, Langford CF, Lehvaslaiho MH, Leversha MA, McCann OT, McDonald LM, McDowall J, Maslen GL, Mistry D, Moschonas NK, Neocleous V, Pearson DM, Phillips KJ, Porter KM, Prathalingam SR, Ramsey YH, Ranby SA, Rice CM, Rogers J, Rogers LJ, Sarafidou T, Scott DJ, Sharp GJ, Shaw-Smith CJ, Smink LJ, Soderlund C, Sotheran EC, Steingruber HE, Sulston JE, Taylor A, Taylor RG, Thorpe AA, Tinsley E, Warry GL, Whittaker A, Whittaker P, Williams SH, Wilmer TE, Wooster R, Wright CL
    Nature. 2001;409;942-3. PMID: 11237015
    
  • A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1.
    Bevan S, Pal T, Greenberg CR, Green H, Wixey J, Bignell G, Narod SA, Foulkes WD, Stratton MR, Houlston RS
    J Clin Endocrinol Metab. 2001;86;3701-4. PMID: 11502798
    
  • Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.
    Clarke PA, te Poele R, Wooster R, Workman P
    Biochem Pharmacol. 2001;62;1311-36. PMID: 11709192
    
  • Cancer and genomics.
    Futreal PA, Kasprzyk A, Birney E, Mullikin JC, Wooster R, Stratton MR
    Nature. 2001;409;850-2. PMID: 11237008
    
  • Confirmation of a gene locus for medullary cystic kidney disease (MCKD2) on chromosome 16p12.
    Hateboer N, Gumbs C, Teare MD, Coles GA, Griffiths D, Ravine D, Futreal PA, Rahman N
    Kidney Int. 2001;60;1233-9. PMID: 11576337
    
  • Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic.
    Martin AM, Blackwood MA, Antin-Ozerkis D, Shih HA, Calzone K, Colligon TA, Seal S, Collins N, Stratton MR, Weber BL, Nathanson KL
    J Clin Oncol. 2001;19;2247-53. PMID: 11304778
    
  • Localization of the gene for distal hereditary motor neuronopathy VII (dHMN-VII) to chromosome 2q14.
    McEntagart M, Norton N, Williams H, Teare MD, Dunstan M, Baker P, Houlden H, Reilly M, Wood N, Harper PS, Futreal PA, Williams N, Rahman N
    Am J Hum Genet. 2001;68;1270-6. PMID: 11294660
    
  • Breast cancer genetics: what we know and what we need.
    Nathanson KL, Wooster R, Weber BL, Nathanson KN
    Nat Med. 2001;7;552-6. PMID: 11329055
    
  • Case of interstitial 12q deletion in association with Wilms tumor.
    Rapley EA, Hargrave D, Persinguhe N, Barfoot R, Moore I, Radford M, Stratton MR, Rahman N, Pritchard-Jones K
    Am J Med Genet. 2001;104;246-9. PMID: 11754052
    
  • Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast.
    Stone JG, Coleman G, Gusterson B, Marossy A, Lakhani SR, Ward A, Nash A, McKinna A, A'Hern R, Stratton MR, Houlston RS
    Cancer Lett. 2001;167;171-4. PMID: 11369138
    

 

• 2000 [Page Top]
• • High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
    Ferguson AT, Evron E, Umbricht CB, Pandita TK, Chan TA, Hermeking H, Marks JR, Lambers AR, Futreal PA, Stampfer MR, Sukumar S
    Proc Natl Acad Sci U S A. 2000;97;6049-54. PMID: 10811911
    
  • The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
    Gayther SA, de Foy KA, Harrington P, Pharoah P, Dunsmuir WD, Edwards SM, Gillett C, Ardern-Jones A, Dearnaley DP, Easton DF, Ford D, Shearer RJ, Kirby RS, Dowe AL, Kelly J, Stratton MR, Ponder BA, Barnes D, Eeles RA
    Cancer Res. 2000;60;4513-8. PMID: 10969800
    
  • The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.
    Lakhani SR, Gusterson BA, Jacquemier J, Sloane JP, Anderson TJ, van de Vijver MJ, Venter D, Freeman A, Antoniou A, McGuffog L, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BA, Futreal PA, Peto J, Stoppa-Lyonnet D, Bignon YJ, Stratton MR
    Clin Cancer Res. 2000;6;782-9. PMID: 10741697
    
  • Familial craniofacial fibrous dysplasia: absence of linkage to GNAS1 and the gene for cherubism.
    Mangion J, Edkins S, Goss AN, Stratton MR, Flanagan AM
    J Med Genet. 2000;37;E37. PMID: 11073546
    
  • Testing for hereditary breast and ovarian cancer in the southeastern United States.
    Miron A, Schildkraut JM, Rimer BK, Winer EP, Sugg Skinner C, Futreal PA, Culler D, Calingaert B, Clark S, Kelly Marcom P, Iglehart JD
    Ann Surg. 2000;231;624-34. PMID: 10767783
    
  • Screening for BRCA2 mutations in 81 Dutch breast-ovarian cancer families.
    Peelen T, van Vliet M, Bosch A, Bignell G, Vasen HF, Klijn JG, Meijers-Heijboer H, Stratton M, van Ommen GJ, Cornelisse CJ, Devilee P
    Br J Cancer. 2000;82;151-6. PMID: 10638982
    
  • Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22.
    Rahman N, Teare MD, Seal S, Renard H, Mangion J, Cour C, Thompson D, Shugart Y, Eccles D, Devilee P, Meijers H, Nathanson KL, Neuhausen SL, Weber B, Chang-Claude J, Easton DF, Goldgar D, Stratton MR
    Oncogene. 2000;19;4170-3. PMID: 10962578
    
  • Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene.
    Rahman N, Stone JG, Coleman G, Gusterson B, Seal S, Marossy A, Lakhani SR, Ward A, Nash A, McKinna A, A'Hern R, Stratton MR, Houlston RS
    Br J Cancer. 2000;82;568-70. PMID: 10682667
    
  • Penetrance of mutations in the familial Wilms tumor gene FWT1.
    Rahman N, Arbour L, Houlston R, Bonaïti-Pellié C, Abidi F, Tranchemontagne J, Ford D, Narod S, Pritchard-Jones K, Foulkes WD, Schwartz C, Stratton MR
    J Natl Cancer Inst. 2000;92;650-2. PMID: 10772684
    
  • Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2.
    Rapley EA, Barfoot R, Bonaïti-Pellié C, Chompret A, Foulkes W, Perusinghe N, Reeve A, Royer-Pokora B, Schumacher V, Shelling A, Skeen J, de Tourreil S, Weirich A, Pritchard-Jones K, Stratton MR, Rahman N
    Br J Cancer. 2000;83;177-83. PMID: 10901367
    
  • Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours.
    Rapley EA, Crockford GP, Teare D, Biggs P, Seal S, Barfoot R, Edwards S, Hamoudi R, Heimdal K, Fossâ SD, Tucker K, Donald J, Collins F, Friedlander M, Hogg D, Goss P, Heidenreich A, Ormiston W, Daly PA, Forman D, Oliver TD, Leahy M, Huddart R, Cooper CS, Bodmer JG, Easton DF, Stratton MR, Bishop DT
    Nat Genet. 2000;24;197-200. PMID: 10655070
    
  • Rapid detection of DNA sequence variants by conformation-sensitive capillary electrophoresis.
    Rozycka M, Collins N, Stratton MR, Wooster R
    Genomics. 2000;70;34-40. PMID: 11087659
    
  • BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers.
    Shih HA, Nathanson KL, Seal S, Collins N, Stratton MR, Rebbeck TR, Weber BL
    Clin Cancer Res. 2000;6;4259-64. PMID: 11106241
    
  • Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding.
    Webster MT, Rozycka M, Sara E, Davis E, Smalley M, Young N, Dale TC, Wooster R
    Genes Chromosomes Cancer. 2000;28;443-53. PMID: 10862053
    
  • Prevalence of BRCA1 and BRCA2 mutations in male breast cancer patients in Canada.
    Wolpert N, Warner E, Seminsky MF, Futreal A, Narod SA
    Clin Breast Cancer. 2000;1;57-63; discussion 64-5. PMID: 11899391
    
  • Cancer classification with DNA microarrays is less more?
    Wooster R
    Trends Genet. 2000;16;327-9. PMID: 10904257
    
  • Cancer classification with DNA microarrays is less more?
    Wooster R
    Trends Genet. 2000;16;327-9. PMID: 10904257
    

 

• 1999 [Page Top]
• • Genetic susceptibility testing and prophylactic oophorectomy.
    Berchuck A, Carney ME, Futreal PA
    Eur J Obstet Gynecol Reprod Biol. 1999;82;159-64. PMID: 10206409
    
  • Managing hereditary ovarian cancer risk.
    Berchuck A, Schildkraut JM, Marks JR, Futreal PA
    Cancer. 1999;86;2517-24. PMID: 10630177
    
  • Genetic alterations in 'normal' luminal and myoepithelial cells of the breast.
    Lakhani SR, Chaggar R, Davies S, Jones C, Collins N, Odel C, Stratton MR, O'Hare MJ
    J Pathol. 1999;189;496-503. PMID: 10629549
    
  • Bcl10 is not a target for frequent mutation in human carcinomas.
    Lambers AR, Gumbs C, Ali S, Marks JR, Iglehart JD, Berchuck A, Futreal PA
    Br J Cancer. 1999;80;1575-6. PMID: 10408401
    
  • A gene for lymphedema-distichiasis maps to 16q24.3.
    Mangion J, Rahman N, Mansour S, Brice G, Rosbotham J, Child AH, Murday VA, Mortimer PS, Barfoot R, Sigurdsson A, Edkins S, Sarfarazi M, Burnand K, Evans AL, Nunan TO, Stratton MR, Jeffery S
    Am J Hum Genet. 1999;65;427-32. PMID: 10417285
    
  • The gene for cherubism maps to chromosome 4p16.3.
    Mangion J, Rahman N, Edkins S, Barfoot R, Nguyen T, Sigurdsson A, Townend JV, Fitzpatrick DR, Flanagan AM, Stratton MR
    Am J Hum Genet. 1999;65;151-7. PMID: 10364527
    
  • Allelotype of uterine leiomyomas.
    Mao X, Barfoot R, Hamoudi RA, Easton DF, Flanagan AM, Stratton MR
    Cancer Genet Cytogenet. 1999;114;89-95. PMID: 10549262
    
  • Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer.
    Peto J, Collins N, Barfoot R, Seal S, Warren W, Rahman N, Easton DF, Evans C, Deacon J, Stratton MR
    J Natl Cancer Inst. 1999;91;943-9. PMID: 10359546
    
  • Linkage analysis of 56 multiplex families excludes the Cowden disease gene PTEN as a major contributor to familial breast cancer.
    Shugart YY, Cour C, Renard H, Lenoir G, Goldgar D, Teare D, Easton D, Rahman N, Gusterton R, Seal S, Barfoot R, Stratton M, Mangion J, Peelen T, van den Ouweland A, Meijers H, Devilee P, Eccles D, Lynch H, Weber B, Stoppa-Lyonnet D, Bignon YJ, Chang-Claude J
    J Med Genet. 1999;36;720-1. PMID: 10507734
    
  • Familial testicular cancer: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family.
    Teh BT, Linblad K, Nord B, Kytölä S, Schalling M, Larsson C, Rapley E, Biggs P, Huddart R, Stratton M
    J Med Genet. 1999;36;348-9. PMID: 10227410
    
  • Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.
    Tomlinson I, Rahman N, Frayling I, Mangion J, Barfoot R, Hamoudi R, Seal S, Northover J, Thomas HJ, Neale K, Hodgson S, Talbot I, Houlston R, Stratton MR
    Gastroenterology. 1999;116;789-95. PMID: 10092300
    

 

• 1998 [Page Top]
• • Frequency of germline and somatic BRCA1 mutations in ovarian cancer.
    Berchuck A, Heron KA, Carney ME, Lancaster JM, Fraser EG, Vinson VL, Deffenbaugh AM, Miron A, Marks JR, Futreal PA, Frank TS
    Clin Cancer Res. 1998;4;2433-7. PMID: 9796975
    
  • Familial breast-ovarian cancer syndromes: BRCA1 and BRCA2.
    Berchuck A, Carney M, Lancaster JM, Marks J, Futreal AP
    Clin Obstet Gynecol. 1998;41;157-66. PMID: 9504233
    
  • Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer.
    Bignell GR, Barfoot R, Seal S, Collins N, Warren W, Stratton MR
    Cancer Res. 1998;58;1384-6. PMID: 9537235
    
  • Effect of smoking on breast cancer in carriers of mutant BRCA1 or BRCA2 genes.
    Brunet JS, Ghadirian P, Rebbeck TR, Lerman C, Garber JE, Tonin PN, Abrahamson J, Foulkes WD, Daly M, Wagner-Costalas J, Godwin A, Olopade OI, Moslehi R, Liede A, Futreal PA, Weber BL, Lenoir GM, Lynch HT, Narod SA
    J Natl Cancer Inst. 1998;90;761-6. PMID: 9605646
    
  • Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers.
    Carney ME, Maxwell GL, Lancaster JM, Gumbs C, Marks J, Berchuck A, Futreal PA
    J Soc Gynecol Investig. 1998;5;281-5. PMID: 9773405
    
  • Using gene carrier probability to select high risk families for identifying germline mutations in breast cancer susceptibility genes.
    Chang-Claude J, Dong J, Schmidt S, Shayeghi M, Komitowski D, Becher H, Stratton MR, Royer-Pokora B
    J Med Genet. 1998;35;116-21. PMID: 9507390
    
  • Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
    Ford D, Easton DF, Stratton M, Narod S, Goldgar D, Devilee P, Bishop DT, Weber B, Lenoir G, Chang-Claude J, Sobol H, Teare MD, Struewing J, Arason A, Scherneck S, Peto J, Rebbeck TR, Tonin P, Neuhausen S, Barkardottir R, Eyfjord J, Lynch H, Ponder BA, Gayther SA, Zelada-Hedman M
    Am J Hum Genet. 1998;62;676-89. PMID: 9497246
    
  • Report of the fourth international workshop on human chromosome 1 mapping 1998
    Gregory SG, Vaudin M, Wooster R, Coleman M, Mischke D, Porter C, Schutte BC, White P, Vance JM
    Cytogenet Cell Genet. 1998;83;147-75. PMID: 10072573
    
  • A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
    Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Höglund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A, Aaltonen LA
    Nature. 1998;391;184-7. PMID: 9428765
    
  • BRCA1 and BRCA2 in breast cancer families from Wales: moderate mutation frequency and two recurrent mutations in BRCA1.
    Lancaster JM, Carney ME, Gray J, Myring J, Gumbs C, Sampson J, Wheeler D, France E, Wiseman R, Harper P, Futreal PA
    Br J Cancer. 1998;78;1417-20. PMID: 9836472
    
  • Identification of two distinct deleted regions on chromosome 13 in prostate cancer.
    Li C, Larsson C, Futreal A, Lancaster J, Phelan C, Aspenblad U, Sundelin B, Liu Y, Ekman P, Auer G, Bergerheim US
    Oncogene. 1998;16;481-7. PMID: 9484837
    
  • Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.
    Maxwell GL, Risinger JI, Gumbs C, Shaw H, Bentley RC, Barrett JC, Berchuck A, Futreal PA
    Cancer Res. 1998;58;2500-3. PMID: 9635567
    
  • Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.
    Maxwell GL, Risinger JI, Tong B, Shaw H, Barrett JC, Berchuck A, Futreal PA
    Gynecol Oncol. 1998;70;13-6. PMID: 9698466
    
  • Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study.
    Neuhausen SL, Godwin AK, Gershoni-Baruch R, Schubert E, Garber J, Stoppa-Lyonnet D, Olah E, Csokay B, Serova O, Lalloo F, Osorio A, Stratton M, Offit K, Boyd J, Caligo MA, Scott RJ, Schofield A, Teugels E, Schwab M, Cannon-Albright L, Bishop T, Easton D, Benitez J, King MC, Goldgar D
    Am J Hum Genet. 1998;62;1381-8. PMID: 9585613
    
  • Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1.
    Rahman N, Abidi F, Ford D, Arbour L, Rapley E, Tonin P, Barton D, Batcup G, Berry J, Cotter F, Davison V, Gerrard M, Gray E, Grundy R, Hanafy M, King D, Lewis I, Ridolfi Luethy A, Madlensky L, Mann J, O'Meara A, Oakhill T, Skolnick M, Strong L, Stratton MR
    Hum Genet. 1998;103;547-56. PMID: 9860296
    
  • The genetics of breast cancer susceptibility.
    Rahman N, Stratton MR
    Annu Rev Genet. 1998;32;95-121. PMID: 9928476
    
  • A missense mutation in the BRCA2 gene in three siblings with ovarian cancer.
    Roth S, Kristo P, Auranen A, Shayehgi M, Seal S, Collins N, Barfoot R, Rahman N, Klemi PJ, Grénman S, Sarantaus L, Nevanlinna H, Butzow R, Ashworth A, Stratton MR, Aaltonen LA
    Br J Cancer. 1998;77;1199-202. PMID: 9579822
    
  • An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer.
    Savelyeva L, Claas A, Gier S, Schlag P, Finke L, Mangion J, Stratton MR, Schwab M
    Cancer Res. 1998;58;863-6. PMID: 9500439
    
  • Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients.
    Shayeghi M, Seal S, Regan J, Collins N, Barfoot R, Rahman N, Ashton A, Moohan M, Wooster R, Owen R, Bliss JM, Stratton MR, Yarnold J
    Br J Cancer. 1998;78;922-7. PMID: 9764584
    
  • Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families.
    Tonin PN, Mes-Masson AM, Futreal PA, Morgan K, Mahon M, Foulkes WD, Cole DE, Provencher D, Ghadirian P, Narod SA
    Am J Hum Genet. 1998;63;1341-51. PMID: 9792861
    
  • Novel regions of allelic deletion on chromosome 18p in tumors of the lung, brain and breast.
    Tran Y, Benbatoul K, Gorse K, Rempel S, Futreal A, Green M, Newsham I
    Oncogene. 1998;17;3499-505. PMID: 10030674
    
  • Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2.
    White PS, Jensen SJ, Rajalingam V, Stairs D, Sulman EP, Maris JM, Biegel JA, Wooster R, Brodeur GM
    Cytogenet Cell Genet. 1998;81;60-4. PMID: 9691177
    
  • Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2.
    White PS, Jensen SJ, Rajalingam V, Stairs D, Sulman EP, Maris JM, Biegel JA, Wooster R, Brodeur GM
    Cytogenet Cell Genet. 1998;81;60-4. PMID: 9691177
    

 

• 1997 [Page Top]
• • Screening for ESR mutations in breast and ovarian cancer patients.
    Anderson TI, Wooster R, Laake K, Collins N, Warren W, Skrede M, Elles R, Tveit KM, Johnston SR, Dowsett M, Olsen AO, Møller P, Stratton MR, Børresen-Dale AL
    Hum Mutat. 1997;9;531-6. PMID: 9195227
    
  • The BRC repeats are conserved in mammalian BRCA2 proteins.
    Bignell G, Micklem G, Stratton MR, Ashworth A, Wooster R
    Hum Mol Genet. 1997;6;53-8. PMID: 9002670
    
  • Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer.
    Bignell GR, Canzian F, Shayeghi M, Stark M, Shugart YY, Biggs P, Mangion J, Hamoudi R, Rosenblatt J, Buu P, Sun S, Stoffer SS, Goldgar DE, Romeo G, Houlston RS, Narod SA, Stratton MR, Foulkes WD
    Am J Hum Genet. 1997;61;1123-30. PMID: 9345104
    
  • Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers.
    Collins N, Wooster R, Stratton MR
    Br J Cancer. 1997;76;1150-6. PMID: 9365162
    
  • Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.
    Connor F, Smith A, Wooster R, Stratton M, Dixon A, Campbell E, Tait TM, Freeman T, Ashworth A
    Hum Mol Genet. 1997;6;291-300. PMID: 9063750
    
  • Novel transcribed sequences within the BWS/WT2 region in 11p15.5: tissue-specific expression correlates with cancer type.
    Crider-Miller SJ, Reid LH, Higgins MJ, Nowak NJ, Shows TB, Futreal PA, Weissman BE
    Genomics. 1997;46;355-63. PMID: 9441738
    
  • Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.
    Dunning AM, Chiano M, Smith NR, Dearden J, Gore M, Oakes S, Wilson C, Stratton M, Peto J, Easton D, Clayton D, Ponder BA
    Hum Mol Genet. 1997;6;285-9. PMID: 9063749
    
  • Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13.
    Easton DF, Steele L, Fields P, Ormiston W, Averill D, Daly PA, McManus R, Neuhausen SL, Ford D, Wooster R, Cannon-Albright LA, Stratton MR, Goldgar DE
    Am J Hum Genet. 1997;61;120-8. PMID: 9245992
    
  • Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene.
    Gayther SA, Mangion J, Russell P, Seal S, Barfoot R, Ponder BA, Stratton MR, Easton D
    Nat Genet. 1997;15;103-5. PMID: 8988179
    
  • Linkage analysis of candidate regions for coeliac disease genes.
    Houlston RS, Tomlinson IP, Ford D, Seal S, Marossy AM, Ferguson A, Holmes GK, Hosie KB, Howdle PD, Jewell DP, Godkin A, Kerr GD, Kumar P, Logan RF, Love AH, Johnston S, Marsh MN, Mitton S, O'Donoghue D, Roberts A, Walker-Smith JA, Stratton MF
    Hum Mol Genet. 1997;6;1335-9. PMID: 9259281
    
  • BRCA 1 and 2--A Genetic Link to Familial Breast and Ovarian Cancer.
    Lancaster JM, Carney ME, Futreal PA
    Medscape Womens Health. 1997;2;7. PMID: 9746681
    
  • Dideoxy fingerprinting assay for BRCA1 mutation analysis.
    Lancaster JM, Berchuck A, Futreal PA, Wiseman RW
    Mol Carcinog. 1997;19;176-9. PMID: 9254884
    
  • BRCA1 expression is not directly responsive to estrogen.
    Marks JR, Huper G, Vaughn JP, Davis PL, Norris J, McDonnell DP, Wiseman RW, Futreal PA, Iglehart JD
    Oncogene. 1997;14;115-21. PMID: 9010238
    
  • Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene.
    McAllister KA, Haugen-Strano A, Hagevik S, Brownlee HA, Collins NK, Futreal PA, Bennett LM, Wiseman RW
    Cancer Res. 1997;57;3121-5. PMID: 9242436
    
  • The familial Wilms' tumour susceptibility gene, FWT1, may not be a tumour suppressor gene.
    Rahman N, Arbour L, Tonin P, Baruchel S, Pritchard-Jones K, Narod SA, Stratton MR
    Oncogene. 1997;14;3099-102. PMID: 9223674
    
  • Report and abstracts of the third international workshop on human chromosome 1 mapping 1997.
    Vance JM, Matise TC, Wooster R, Schutte BC, Bruns GA, van Roy N, Brodeur GM, Tao YX, Gregory S, Weith A, Vaudin M, White P
    Cytogenet Cell Genet. 1997;78;154-82. PMID: 9465885
    
  • Report and abstracts of the third international workshop on human chromosome 1 mapping 1997.
    Vance JM, Matise TC, Wooster R, Schutte BC, Bruns GA, van Roy N, Brodeur GM, Tao YX, Gregory S, Weith A, Vaudin M, White P
    Cytogenet Cell Genet. 1997;78;154-82. PMID: 9465885
    
  • The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas.
    Biggs PJ, Chapman P, Lakhani SR, Burn J, Stratton MR
    Oncogene. 1996;12;1375-7. PMID: 8649842
    
  • Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.
    Lakhani SR, Slack DN, Hamoudi RA, Collins N, Stratton MR, Sloane JP
    Lab Invest. 1996;74;129-35. PMID: 8569175
    

 

• 1996 [Page Top]
• • Role of BRCA1 mutation screening in the management of familial ovarian cancer.
    Berchuck A, Cirisano F, Lancaster JM, Schildkraut JM, Wiseman RW, Futreal A, Marks JR
    Am J Obstet Gynecol. 1996;175;738-46. PMID: 8828444
    
  • BRCA2 mutations in primary breast and ovarian cancers.
    Lancaster JM, Wooster R, Mangion J, Phelan CM, Cochran C, Gumbs C, Seal S, Barfoot R, Collins N, Bignell G, Patel S, Hamoudi R, Larsson C, Wiseman RW, Berchuck A, Iglehart JD, Marks JR, Ashworth A, Stratton MR, Futreal PA
    Nat Genet. 1996;13;238-40. PMID: 8640235
    
  • Detection of BRCA1 mutations in women with early-onset ovarian cancer by use of the protein truncation test.
    Lancaster JM, Cochran CJ, Brownlee HA, Evans AC, Berchuck A, Futreal PA, Wiseman RW
    J Natl Cancer Inst. 1996;88;552-4. PMID: 8606385
    
  • Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer.
    Lancaster JM, Brownlee HA, Bell DA, Futreal PA, Marks JR, Berchuck A, Wiseman RW, Taylor JA
    Mol Carcinog. 1996;17;160-2. PMID: 8944076
    
  • A polymorphic stop codon in BRCA2.
    Mazoyer S, Dunning AM, Serova O, Dearden J, Puget N, Healey CS, Gayther SA, Mangion J, Stratton MR, Lynch HT, Goldgar DE, Ponder BA, Lenoir GM
    Nat Genet. 1996;14;253-4. PMID: 8896551
    
  • Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.
    Neuhausen SL, Mazoyer S, Friedman L, Stratton M, Offit K, Caligo A, Tomlinson G, Cannon-Albright L, Bishop T, Kelsell D, Solomon E, Weber B, Couch F, Struewing J, Tonin P, Durocher F, Narod S, Skolnick MH, Lenoir G, Serova O, Ponder B, Stoppa-Lyonnet D, Easton D, King MC, Goldgar DE
    Am J Hum Genet. 1996;58;271-80. PMID: 8571953
    
  • Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families.
    Phelan CM, Lancaster JM, Tonin P, Gumbs C, Cochran C, Carter R, Ghadirian P, Perret C, Moslehi R, Dion F, Faucher MC, Dole K, Karimi S, Foulkes W, Lounis H, Warner E, Goss P, Anderson D, Larsson C, Narod SA, Futreal PA
    Nat Genet. 1996;13;120-2. PMID: 8673090
    
  • Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus.
    Phelan CM, Rebbeck TR, Weber BL, Devilee P, Ruttledge MH, Lynch HT, Lenoir GM, Stratton MR, Easton DF, Ponder BA, Cannon-Albright L, Larsson C, Goldgar DE, Narod SA
    Nat Genet. 1996;12;309-11. PMID: 8589723
    
  • The human mammary-derived growth inhibitor (MDGI) gene: genomic structure and mutation analysis in human breast tumors.
    Phelan CM, Larsson C, Baird S, Futreal PA, Ruttledge MH, Morgan K, Tonin P, Hung H, Korneluk RG, Pollak MN, Narod SA
    Genomics. 1996;34;63-8. PMID: 8661024
    
  • Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12-q21.
    Rahman N, Arbour L, Tonin P, Renshaw J, Pelletier J, Baruchel S, Pritchard-Jones K, Stratton MR, Narod SA
    Nat Genet. 1996;13;461-3. PMID: 8696342
    
  • Terminology for carcinoma-in-situ of the breast.
    Sloane JP, Lakhani SR, Stratton MR
    Lancet. 1996;347;1259-60. PMID: 8622469
    
  • Recent advances in understanding of genetic susceptibility to breast cancer.
    Stratton MR
    Hum Mol Genet. 1996;5 Spec No;1515-9. PMID: 8875258
    
  • Hereditary predisposition to breast cancer.
    Stratton MR, Wooster R
    Curr Opin Genet Dev. 1996;6;93-7. PMID: 8791478
    

 

• 1995 [Page Top]
• • BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.
    Vaughn JP, Davis PL, Jarboe MD, Huper G, Evans AC, Wiseman RW, Berchuck A, Iglehart JD, Futreal PA, Marks JR
    Cell Growth Differ. 1996;7;711-5. PMID: 8780884
    
  • Cell cycle control of BRCA2.
    Vaughn JP, Cirisano FD, Huper G, Berchuck A, Futreal PA, Marks JR, Iglehart JD
    Cancer Res. 1996;56;4590-4. PMID: 8840967
    
  • Evidence for two senescence loci on human chromosome 1.
    Vojta PJ, Futreal PA, Annab LA, Kato H, Pereira-Smith OM, Barrett JC
    Genes Chromosomes Cancer. 1996;16;55-63. PMID: 9162198
    
  • Evidence for two senescence loci on human chromosome 1.
    Vojta PJ, Futreal PA, Annab LA, Kato H, Pereira-Smith OM, Barrett JC
    Genes Chromosomes Cancer. 1996;16;55-63. PMID: 9162198
    
  • Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene.
    Biggs PJ, Wooster R, Ford D, Chapman P, Mangion J, Quirk Y, Easton DF, Burn J, Stratton MR
    Nat Genet. 1995;11;441-3. PMID: 7493027
    
  • Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13.
    Cleton-Jansen AM, Collins N, Lakhani SR, Weissenbach J, Devilee P, Cornelisse CJ, Stratton MR
    Br J Cancer. 1995;72;1241-4. PMID: 7577475
    
  • Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.
    Collins N, McManus R, Wooster R, Mangion J, Seal S, Lakhani SR, Ormiston W, Daly PA, Ford D, Easton DF
    Oncogene. 1995;10;1673-5. PMID: 7731724
    
  • A 45-year follow-up of kindred 107 and the search for BRCA2.
    Goldgar DE, Neuhausen SL, Steele L, Fields P, Ward JH, Tran T, Ngyuen K, Stratton MR, Easton DF
    J Natl Cancer Inst Monogr. 1995;15-9. PMID: 8573446
    
  • Genetics of non-medullary thyroid cancer.
    Houlston RS, Stratton MR
    QJM. 1995;88;685-93. PMID: 7493165
    
  • Microsatellite instability in human testicular germ cell tumours.
    Huddart RA, Wooster R, Horwich A, Cooper CS
    Br J Cancer. 1995;72;642-5. PMID: 7669575
    
  • Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p.
    Lakhani SR, Collins N, Stratton MR, Sloane JP
    J Clin Pathol. 1995;48;611-5. PMID: 7560165
    
  • Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.
    Norris J, Fan D, Aleman C, Marks JR, Futreal PA, Wiseman RW, Iglehart JD, Deininger PL, McDonnell DP
    J Biol Chem. 1995;270;22777-82. PMID: 7559405
    
  • Loss of heterozygosity in ductal carcinoma in situ of the breast.
    Stratton MR, Collins N, Lakhani SR, Sloane JP
    J Pathol. 1995;175;195-201. PMID: 7738715
    
  • Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours.
    Warren W, Biggs PJ, el-Baz M, Ghoneim MA, Stratton MR, Venitt S
    Carcinogenesis. 1995;16;1181-9. PMID: 7767983
    
  • Breast cancer susceptibility: a complex disease unravels.
    Wooster R, Stratton MR
    Trends Genet. 1995;11;3-5. PMID: 7900193
    
  • Identification of the breast cancer susceptibility gene BRCA2.
    Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G
    Nature. 1995;378;789-92. PMID: 8524414
    

 

• 1994 [Page Top]
• • The genetics of familial breast cancer and their practical implications.
    Eeles RA, Stratton MR, Goldgar DE, Easton DF
    Eur J Cancer. 1994;30A;1383-90. PMID: 7999429
    
  • Familial cancer syndromes.
    Eng C, Stratton M, Ponder B, Murday V, Easton D, Sacks N, Watson M, Eeles R
    Lancet. 1994;343;709-13. PMID: 7907684
    
  • BRCA1 mutations in primary breast and ovarian carcinomas.
    Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y
    Science. 1994;266;120-2. PMID: 7939630
    
  • Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.
    Futreal PA, Cochran C, Rosenthal J, Miki Y, Swenson J, Hobbs M, Bennett LM, Haugen-Strano A, Marks J, Barrett JC
    Hum Mol Genet. 1994;3;1359-64. PMID: 7987315
    
  • Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
    Futreal PA, Cochran C, Marks JR, Iglehart JD, Zimmerman W, Barrett JC, Wiseman RW
    Cancer Res. 1994;54;1791-4. PMID: 7511052
    
  • Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1.
    Kamb A, Futreal PA, Rosenthal J, Cochran C, Harshman KD, Liu Q, Phelps RS, Tavtigian SV, Tran T, Hussey C
    Genomics. 1994;23;163-7. PMID: 7829067
    
  • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
    Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W
    Science. 1994;266;66-71. PMID: 7545954
    
  • Localisation of the breast-ovarian cancer susceptibility gene (BRCA1) on 17q12-21 to an interval of < or = 1 cM.
    Smith SA, DiCioccio RA, Struewing JP, Easton DF, Gallion HH, Albertsen H, Mazoyer S, Johansson B, Steichen-Gersdorf E, Stratton M
    Genes Chromosomes Cancer. 1994;10;71-6. PMID: 7519878
    
  • Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.
    Stratton MR, Ford D, Neuhasen S, Seal S, Wooster R, Friedman LS, King MC, Egilsson V, Devilee P, McManus R
    Nat Genet. 1994;7;103-7. PMID: 8075631
    
  • Instability of short tandem repeats (microsatellites) in human cancers.
    Wooster R, Cleton-Jansen AM, Collins N, Mangion J, Cornelis RS, Cooper CS, Gusterson BA, Ponder BA, von Deimling A, Wiestler OD
    Nat Genet. 1994;6;152-6. PMID: 8162069
    
  • Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.
    Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Averill D
    Science. 1994;265;2088-90. PMID: 8091231
    
  • Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.
    Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Averill D
    Science. 1994;265;2088-90. PMID: 8091231
    

 

• 1993 [Page Top]
• • Investigation of the role of G1/S cell cycle mediators in cellular senescence.
    Afshari CA, Vojta PJ, Annab LA, Futreal PA, Willard TB, Barrett JC
    Exp Cell Res. 1993;209;231-7. PMID: 8262140
    
  • Genetic and molecular basis for cellular senescence.
    Barrett JC, Annab LA, Futreal PA
    Adv Exp Med Biol. 1993;330;27-43. PMID: 8368137
    
  • Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.
    Biggs PJ, Warren W, Venitt S, Stratton MR
    Mutagenesis. 1993;8;275-83. PMID: 8377645
    
  • Familial progressive supranuclear palsy.
    Brown J, Lantos P, Stratton M, Roques P, Rossor M
    J Neurol Neurosurg Psychiatry. 1993;56;473-6. PMID: 8505637
    
  • Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings.
    Eeles RA, Warren W, Knee G, Bartek J, Averill D, Stratton MR, Blake PR, Tait DM, Lane DP, Easton DF
    Oncogene. 1993;8;1269-76. PMID: 8479749
    
  • A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus.
    Jacobs IJ, Smith SA, Wiseman RW, Futreal PA, Harrington T, Osborne RJ, Leech V, Molyneux A, Berchuck A, Ponder BA
    Cancer Res. 1993;53;1218-21. PMID: 8095178
    
  • Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
    Smith SA, Easton DF, Ford D, Peto J, Anderson K, Averill D, Stratton M, Ponder M, Pye C, Ponder BA
    Am J Hum Genet. 1993;52;767-76. PMID: 8460642
    
  • Molecular analyses of in situ breast cancer.
    Stratton MR, Collins N, Lakhani S, Sloane J
    Eur J Cancer Prev. 1993;2 Suppl 3;123. PMID: 7905313
    
  • Absence of linkage to the ataxia telangiectasia locus in familial breast cancer.
    Wooster R, Ford D, Mangion J, Ponder BA, Peto J, Easton DF, Stratton MR
    Hum Genet. 1993;92;91-4. PMID: 8365732
    
  • Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-Glucuronosyltransferases stably expressed in tissue culture cell lines.
    Wooster R, Ebner T, Sutherland L, Clarke D, Burchell B
    Toxicology. 1993;82;119-29. PMID: 8236271
    
  • Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-Glucuronosyltransferases stably expressed in tissue culture cell lines.
    Wooster R, Ebner T, Sutherland L, Clarke D, Burchell B
    Toxicology. 1993;82;119-29. PMID: 8236271
    
  • Growth and transformation suppressor genes for BHK Syrian hamster cells on human chromosomes 1 and 11.
    Annab LA, Dong JT, Futreal PA, Satoh H, Oshimura M, Barrett JC
    Mol Carcinog. 1992;6;280-8. PMID: 1485918
    
  • Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.
    Futreal PA, Söderkvist P, Marks JR, Iglehart JD, Cochran C, Barrett JC, Wiseman RW
    Cancer Res. 1992;52;2624-7. PMID: 1568230
    
  • Dinucleotide repeat polymorphism in the THRA1 gene.
    Futreal PA, Barrett JC, Wiseman RW
    Hum Mol Genet. 1992;1;66. PMID: 1301142
    
  • Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region.
    Zimmermann W, Bender E, Rohde K, Reis A, Wiseman R, Futreal A, Krause H, Prokoph H, Werner S, Scherneck S
    Am J Hum Genet. 1993;52;789-91. PMID: 8460645
    

 

• 1992 [Page Top]
• • Chromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A-subfamily).
    Moghrabi N, Sutherland L, Wooster R, Povey S, Boxer M, Burchell B
    Ann Hum Genet. 1992;56 ( Pt 2);81-91. PMID: 1503396
    
  • The p53 gene in human cancer.
    Stratton MR
    Eur J Cancer. 1992;28;293-5. PMID: 1567683
    
  • Molecular genetic study showing that the IN/157 'oligodendroglioma' cell line has been contaminated by rhabdomyosarcoma (RD) cells.
    Venter DJ, Stratton MR, Noble MD
    Neuropathol Appl Neurobiol. 1992;18;159-69. PMID: 1620276
    
  • A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
    Wooster R, Mangion J, Eeles R, Smith S, Dowsett M, Averill D, Barrett-Lee P, Easton DF, Ponder BA, Stratton MR
    Nat Genet. 1992;2;132-4. PMID: 1303262
    
  • A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
    Wooster R, Mangion J, Eeles R, Smith S, Dowsett M, Averill D, Barrett-Lee P, Easton DF, Ponder BA, Stratton MR
    Nat Genet. 1992;2;132-4. PMID: 1303262
    

 

• 1991 [Page Top]
• • Soft tissue tumours: the genetic basis of development.
    Cooper CS, Stratton MR
    Carcinogenesis. 1991;12;155-65. PMID: 1995181
    
  • An Alu polymorphism intragenic to the TP53 gene.
    Futreal PA, Barrett JC, Wiseman RW
    Nucleic Acids Res. 1991;19;6977. PMID: 1762941
    
  • Failure of senescent cells to phosphorylate the RB protein.
    Futreal PA, Barrett JC
    Oncogene. 1991;6;1109-13. PMID: 1861860
    
  • Detection of transforming genes by transfection of DNA from primary soft-tissue tumours.
    Gill S, Stratton MR, Patterson H, Spurr NK, Fisher C, Gusterson BA, Cooper CS
    Oncogene. 1991;6;1651-6. PMID: 1923531
    
  • Investigation of the molecular basis of the genetic deficiency of UDP-glucuronosyltransferase in Crigler-Najjar syndrome.
    Robertson KJ, Clarke D, Sutherland L, Wooster R, Coughtrie MW, Burchell B
    J Inherit Metab Dis. 1991;14;563-79. PMID: 1749222
    
  • A case of cerebellar medulloblastoma with a single chromosome abnormality.
    Stratton MR, Darling J, Cooper CS, Reeves BR
    Cancer Genet Cytogenet. 1991;53;101-3. PMID: 2036631
    
  • Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.
    Wooster R, Sutherland L, Ebner T, Clarke D, Da Cruz e Silva O, Burchell B
    Biochem J. 1991;278 ( Pt 2);465-9. PMID: 1910331
    

 

• 1990 [Page Top]
• • Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase.
    Coffman BL, Tephly TR, Irshaid YM, Green MD, Smith C, Jackson MR, Wooster R, Burchell B
    Arch Biochem Biophys. 1990;281;170-5. PMID: 2116769
    
  • Dinucleotide repeat polymorphism at the SIS locus.
    Patterson H, Mitchell PJ, Cooper CS, Stratton MR
    Nucleic Acids Res. 1990;18;5917. PMID: 2216802
    
  • Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene.
    Stratton MR, Moss S, Warren W, Patterson H, Clark J, Fisher C, Fletcher CD, Ball A, Thomas M, Gusterson BA
    Oncogene. 1990;5;1297-301. PMID: 2216456
    

 

• 1989 [Page Top]
• • Expression of a human liver cDNA encoding a UDP-glucuronosyltransferase catalysing the glucuronidation of hyodeoxycholic acid in cell culture.
    Fournel-Gigleux S, Jackson MR, Wooster R, Burchell B
    FEBS Lett. 1989;243;119-22. PMID: 2492950
    
  • Characterization of the human cell line TE671.
    Stratton MR, Darling J, Pilkington GJ, Lantos PL, Reeves BR, Cooper CS
    Carcinogenesis. 1989;10;899-905. PMID: 2650908
    
  • Cytogenetic abnormalities in human ependymomas.
    Stratton MR, Darling J, Lantos PL, Cooper CS, Reeves BR
    Int J Cancer. 1989;44;579-81. PMID: 2793229
    
  • Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction.
    Stratton MR, Fisher C, Gusterson BA, Cooper CS
    Cancer Res. 1989;49;6324-7. PMID: 2680062
    
  • Misidentified cell.
    Stratton MR, Reeves BR, Cooper CS
    Nature. 1989;337;311-2. PMID: 2911385
    
  • Structural alterations of the RB1 gene in human soft tissue tumours.
    Stratton MR, Williams S, Fisher C, Ball A, Westbury G, Gusterson BA, Fletcher CD, Knight JC, Fung YK, Reeves BR
    Br J Cancer. 1989;60;202-5. PMID: 2765366
    
  • Infection of brain cells by diverse human immunodeficiency virus isolates: role of CD4 as receptor.
    Weber J, Clapham P, McKeating J, Stratton M, Robey E, Weiss R
    J Gen Virol. 1989;70 ( Pt 10);2653-60. PMID: 2677235
    

 

• 1988 [Page Top]
• • Structure of the met protein and variation of met protein kinase activity among human tumour cell lines.
    Tempest PR, Stratton MR, Cooper CS
    Br J Cancer. 1988;58;3-7. PMID: 3048352